Managing research and innovation networks: Evidence from a government sponsored cross-industry program

Important innovations are increasingly produced based on research engagement and fertilization across industries. However, we know little about the challenges associated with managing innovation networks in specific contexts that involves researchers in cross-industry collaboration. Against this backdrop, we draw on theory on design and orchestration of innovation networks to analyze a large-scale government sponsored program, “ProcessIT Innovations” that was designed to increase competitiveness and accelerate economic growth in Northern Sweden. The program was initiated and led by firms from the traditionally strong local process industry and engaged local researchers and firms from the emerging IT industry. Based on our analyses, we offer two contributions. First, we provide a detailed analysis of the challenges related to configuration of the network, orchestration of partnerships between participants, and facilitation of innovation in dedicated development projects. Second, we propose a model of managing research and innovation networks through fertilization across industries and between firms and research institutions.     

A deep vein thrombosis caused by 20209C>T mutation in homozygosis of the prothrombin gene in a Caucasian patient

Introduction:

Additional nucleotide substitutions in the 3′-untranslated region of prothrombin gene could explain some thrombotic events and also adverse pregnancy outcomes. We describe the first case of a homozygous 20209C>T mutation as the cause of deep vein thrombosis in a Spanish patient.

Case and methods:

The 56-year-old male patient with a partial tear of the Achilles tendon developed calf (tibial) deep vein thrombosis after immobilization and was treated with an anticoagulant. To determine if the deep vein thrombosis was of genetic origin, a peripheral blood DNA sample was analysed for the presence of the three most frequent mutations associated with thrombotic events: factor V Leiden (1691G>A), prothrombin (20210G>A) and methylene tetrahydrofolate reductase (677C>T). The presence or absence of the normal allele of prothrombin could not be determined using the PTH-FV-MTHFR StripAssay (Vienna Lab).

Results:

Comprehensive analysis showed that the patient had a variant interfering with the polymerase chain reaction product, we sequenced the entire prothrombin gene and found that the patient had a homozygous C>T mutation at position 20209; this interfered with the polymerase chain reaction product, which needs a C at this position to be able to bind to the wild-type probe present in the test strip.

Conclusion:

The homozygous 20209C>T mutation and the presence of the mutation 677C>T in heterozygosity explained the patient’s deep vein thrombosis because the combination of mutations would increase the risk of thrombosis. Suitable genetic counselling should be provided to the patient and first-degree relatives as it important to detect prothrombin gene variants that could increase risk for thrombotic events.     

Social capital as a driver of local knowledge exchange: a social network analysis

The objective of this paper is to take an in-depth look, from a network perspective, at the role that social capital plays in improving knowledge exchange between organizations. To do this, we consider the three dimensions of social capital: the structural dimension, as measured by the position of firms bridging structural holes; the relational dimension, as gauged by the level of trust and friendship in each relationship; and the cognitive dimension, as estimated by the presence of a shared culture. We also evaluate the level of organizational and human capital present in terms of the firms in the network. Empirical evidence has been gathered from the Madrid Science Park in Spain by applying the social network analysis methodology. The results show that the three dimensions of social capital play a significant role in increasing knowledge exchange in this network, while human and organizational capital differences are only significant for a sub-sample.     

Critical elements for product innovation at Portuguese innovative SMEs: an intellectual capital perspective

Knowledge Management Research & Practice - The general purpose of this research is to study interaction effects between intangible assets and product innovation. More specifically, the authors...     

The relationships among consumers’ ethical ideology,risk aversion and ethically-based distrust of online retailers and the moderating role of consumers’ need for personal interaction

Consumer distrust is only recently beginning to be perceived as an important e-commerce issue and, unlike online trust, the nature and role of distrust is much less established. This study examines the influence of two important consumer characteristics (ethical ideology and risk aversion) on consumer’s ethically-based distrust of online retailers. Also, the moderating role of consumer’s need for personal contact with sales staff is tested. Results from 409 online consumers confirm that both relativist-based ethical ideology and risk aversion are strongly and positively related to consumers’ distrust. Interestingly, our findings show that positive effects of relativism and risk aversion on consumer’s distrust are moderated by consumers’ need for personal interaction, which is more pronounced for those consumers with a high need for personal interaction with retail salespeople.     

Return to play management after concussion in football: recommendations for team physicians

Abstract

A concussion is a rare but potentially serious injury of football players. Thus, an immediate and valid diagnosis, estimate of severity and therapeutic management is required. To summarise the published information on management of concussion with respect to a safe return to play (RTP), a literature search was conducted. Current guidelines on concussion in sports and significant studies on concussion in football were analysed. After concussion, management and RTP decision should remain in the area of clinical judgement on an individualised basis according to the current international guidelines. If a concussion is suspected, the player should not be allowed to RTP the same day. The RTP programme should follow a gradual step-wise procedure. A concussed player should not RTP unless he/she is asymptomatic and the neurological and neuropsychological examinations are normal. Untimely RTP bears an increased risk of sustaining another more severe brain injury and repetitive brain injury of long-term sequelae. In football, the management of concussion should primarily follow the recommendations proposed by the Concussion in Sports Group. Information and education of players and their medical and coaching team help to protect the players’ health. Future studies on concussion should include validated and detailed information on RTP protocols.     

Healthy Competition? The Public Interest in International Radiotelegraphy, 1919–1940

This article traces the definition of the public interest from the Navy Department through the FRC, to the FCC, with regard to the right mixture of competition and monopoly in international radiotelegraphy and identifies foreign policy as an important policy area where regulatory autonomy is enhanced. Policymakers defined the public interest independently of industry pressure because of internal divisions in the industry and, more importantly, because the strategic and international dimensions of the policy area brought the Navy Department into the regulatory mix and prompted the Commission to adopt a realist, rather than a liberal, framework.     

A Critique of Educational Research

Abstract

Instrumentalist theories are older than liberal, reconstructionist or child‐centred ones and the concept of progress they embody seems very obvious at first sight: making schools and other educational institutions more relevant to social needs. In open market societies however social needs are even more fiercely contested than are intrinsic educational values or the needs of individual childen. When a social need is politically legitimated in newly closed societies, even resolute instrumentalists may blanch at what is required of schools, as Durkheim's disciples found in occupied France. In contemporary English‐speaking societies the paradox is noted that neo‐Marxists consider educational institutions to be instruments in the hands of the ‘ruling classes’ and to be part of an Ideological State Apparatus (ISA), whereas all those who may be defined as members of such ruling classes bemoan that these institutions are dysfunctional to the needs of industry and commerce and hostile to market societies.