Alterations in autonomic cardiac modulation in response to normobaric hypoxia

Purpose: The present study aimed to determine if autonomic cardiac modulation was influenced by acute exposure to normobaric hypoxia. Method: Ten healthy male lowland dwellers completed five block-randomised single-blinded, crossed-over acute exposures to a normobaric hypoxic environment, each separated by 24 hours’ recovery (20.3%, 17.4%, 14.5%, 12.0% and 9.8% F_IO₂). Supine recordings were made of arterial oxygen saturation and electrocardiogram (ECG). RR intervals from the ECG trace were analysed for time (SDNN, lnrMSSD), frequency (lnVLF, lnLF, lnHF, lnTP, LFnu, and HFnu), and nonlinear (DFA-α1 and SampEn) heart rate variability components. Results: A significant reduction in arterial SaO₂ occurred with reduced F_IO₂, along with a rise in heart rate (Cohen’s d?=?1.16, 95% Confidence Interval [2.64–6.46]), significant at 9.8% F_IO₂. A decrease in autonomic cardiac modulation was also found as shown by a statistically significant (at 9.8% F_IO₂) decrease in lnTP (d?=?1.84 [1.74–1.94]), and SampEn (d?=?0.98 [0.83–1.12]) and an increase in DFA-α₁ (d?=?0.72 [0.60–0.84]) from normoxia at 9.8% F_IO₂. Conclusion: The decrease in variability indicated a reduction in autonomic cardiac modulation. There appears to be a threshold ～9.8% F_IO₂ (～6000?m equiv.), below which significant alterations in autonomic control occur.     

Comparison of three web-scale discovery services for health sciences research

Objective

The purpose of this study was to investigate the relative effectiveness of three web-scale discovery (WSD) tools in answering health sciences search queries.

Methods

Simple keyword searches, based on topics from six health sciences disciplines, were run at multiple real-world implementations of EBSCO Discovery Service (EDS), Ex Libris''s Primo, and ProQuest''s Summon. Each WSD tool was evaluated in its ability to retrieve relevant results and in its coverage of MEDLINE content.

Results

All WSD tools returned between 50%–60% relevant results. Primo returned a higher number of duplicate results than the other 2 WSD products. Summon results were more relevant when search terms were automatically mapped to controlled vocabulary. EDS indexed the largest number of MEDLINE citations, followed closely by Summon. Additionally, keyword searches in all 3 WSD tools retrieved relevant material that was not found with precision (Medical Subject Headings) searches in MEDLINE.

Conclusions

None of the 3 WSD products studied was overwhelmingly more effective in returning relevant results. While difficult to place the figure of 50%–60% relevance in context, it implies a strong likelihood that the average user would be able to find satisfactory sources on the first page of search results using a rudimentary keyword search. The discovery of additional relevant material beyond that retrieved from MEDLINE indicates WSD tools'' value as a supplement to traditional resources for health sciences researchers.     

Silent Majority: Childhood Vaccinations and Antecedents to Communicative Action

The topic of childhood vaccinations has received much news media attention recently, prompting scholars to examine how the public has responded. In light of this news, and the deep divide that seems to exist between parents who support childhood vaccinations and those who do not, this study examines how and why individuals may involve themselves in communication about vaccinations, particularly on social media or in other online environments. Focusing on the concept of communicative action and drawing from spiral of silence and other research, a survey of mothers (N = 455) found that those who do not support childhood vaccinations are more likely to engage in communication about the issue, including information seeking, attending, forefending, permitting, forwarding, and sharing. In addition, issue importance and affective and cognitive involvement help drive communicative action regarding childhood vaccinations, which could affect public opinion or public perceptions of the issue. Theoretical and practical implications are discussed.     

Starting and Sustaining an Undergraduate Research Program: The SURIEM Experience at Michigan State University

Abstract

Mentoring undergraduate students in research is both rewarding and challenging. In this paper we present how we established a summer Research Experience for Undergraduates (REU) program in the mathematical sciences at Michigan State University. A goal of our REU is to include students who are at an early stage of their study of mathematics. We share our experiences in recruiting students, designing research projects, and mentoring our participants. We discuss the challenges we faced and the solutions we found while working with a diverse group of undergraduate students from across the nation.     

Attitudes of Business Faculty Towards Two Methods of Collecting Teaching Evaluations: Paper vs. Online

Business professors were surveyed to determine their attitudes towards two methods of collecting students' teaching evaluations of faculty--the traditional paper-and-pencil method conducted in class and the online method conducted via the Internet. Faculty preferred the traditional paper method, mainly because they believed it would produce a higher and more accurate response than the online method. Faculty characteristics were examined to determine whether they were related to attitudes towards the online method of collecting teaching evaluations. No characteristics were found to be significantly associated with attitudes towards the online method. Suggestions for future researchers are offered.     

Identification of Alcohol by Smell among Preschoolers: Evidence for Early Socialization about Drugs Occurring in the Home

This study tested preschoolers' ability to provide accurate verbal associations to alcoholic beverage odors and whether this ability was related to parental drinking patterns and motivations. Older preschoolers performed better than younger preschoolers; photographic cues improved performance; children who correctly identified a substance by smell had socially appropriate knowledge of the culturally appropriate users of the substance; children reported liking substances that are used mainly by children and adults, and generally reported disliking substances whose use is legally limited to adults only; children were better at identifying substances they commonly use, but success at recognition of alcoholic beverages was related to heavier parental drinking and use of alcohol for escape reasons. Findings have implications for theories of socialization to drug use and for models of prevention.     

Using a Substitute Activity to Eliminate Eye Poking in a 3‐year‐old Visually Impaired Child in the Classroom

This paper documents the effectiveness of a substitute activity in decreasing the frequency of eye poking in a 3‐year‐old nonretarded visually impaired child who was involved in a highly participatory, full‐day reading program with four sighted classmates. Following 49 days of training, eye poking had been eliminated, and the subject was able to read 25 word cards. Elements to consider when selecting a substitute activity to interrupt an established self‐stimulating behaviour such as eye poking are discussed.     

Matching Cloze as an Evaluation Procedure for Slow Learning Children

The matching cloze procedure, which does not require language production skills and which is simple enough for the classroom teacher to construct unaided, was originally developed to measure reading skills of elementary English‐second‐language pupils. The results of this pilot study with opportunity school children indicate the validity of the procedure as an evaluation technique for slow learning children.