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81.
Ritu Sharma Mridula Mahajan Ravi Kant 《Indian journal of clinical biochemistry : IJCB》2004,19(1):10-13
Serum total lipids (cholesterol and triglyceride), lipoproteins (VLDL, LDL and HDL) and Apolipoprotein-B levels of normal
healthy individuals (n=25) and coronary artery disease patients (n=25) were estimated. The objective of the present study
was to ascertain the role of apo-B in causation and inheritance of coronary artery disease. It was observed that on an average
serum total cholesterol and triglyceride more than 200 mg/dl bring the individuals to a risk of coronary artery disease (CAD)
irrespective of the age. CAD patients achieved this value at an early age (35–45 years). Similarly VLDL and LDL levels were
found to be significantly raised in CAD patients when compared to that of age matched normal individuals, with patients achieving
risk values at an early age. HDL levels were found to be significantly lower in CAD patients as compared to normal individuals.
Serum apo-B levels were significantly raised in CAD patients as compared to age matched normal individuals. Patients with
positive family history of CAD had raised serum apo-B levels than those having negative family history. A positive coefficient
of correlation was observed between serum apo-B and LDL levels suggesting that more the number of Apo-B particles, more will
be the synthesis of atherogenic particle (LDL). Patients with negative family history had serum apo-B levels closer to those
of normal individuals and in these individuals HDL levels were found to be significantly lowered, suggesting that loss of
scavenger role of HDL could be the risk factor responsible for the causation of CAD in these patients, with negative family
history of coronary artery disease. 相似文献
82.
Miriam Delgado-Verde Javier Amores-Salvadó Gregorio Martín-de Castro José Emilio Navas-López 《知识管理研究与实践》2014,12(3):261-275
Although the importance of intellectual capital has already been highlighted in the management literature, few articles have focused on the importance of its green counterpart, green intellectual capital. Nowadays, when environmental concerns cannot be ignored by firms, it is therefore time to explore the role of green intellectual capital in environmental improvement. For that reason, our research aims to explore the relationships between green intellectual capital components and the environmental performance of the firms. In particular, we try to show the importance of green organizational and social capital in the development of environmental product innovations, which are vital to the development and implementation of environmental strategies since, as scholars have pointed out, they generate some of the greatest environmental impacts. The empirical results show that green organizational capital has an indirect impact on environmental product innovation through green social capital, meaning that the latter is a significant mediator of that relationship, and at the same time emphasizing that informal relationships play a key role in the improvement of the environmental performance of the firm and, more specifically, in the development of environmental product innovations. 相似文献
83.
This study aims to examine the relationships between managerial learning as a facet of knowledge absorption (KA), firm innovation as a facet of knowledge exploitation (KE), and performance of small firms (i.e., firms with fewer than 50 employees). It builds on the knowledge-based view of the firm and the upper echelons theory to describe the effects of KA on KE, and that of KE on firm performance, in the small-firm context. Using survey data of 1441 small firms in New Zealand, the study applies a partial least squares approach to structural equation modelling to test the main hypotheses of the study. The main findings show the positive and significant effects of three types of managerial learning, namely, practice-based, proximal, and distal learning, on innovation and on innovation in firm performance. However, the curvilinear relationships suggest rather that the effects are finite and, potentially, confounded by factors unaccounted for in the models. 相似文献
84.
Kristina Andersson 《Cultural Studies of Science Education》2017,12(2):425-433
Marie Ståhl and Anita Hussénius have defined what discourses dominate national tests in chemistry for Grade 9 in Sweden by using feminist, critical didactic perspectives. This response seeks to expand the results in Ståhl and Hussénius’s article Chemistry inside an epistemological community box!—Discursive exclusions and inclusions in the Swedish national tests in chemistry, by using different facets of gender awareness. The first facet—Gender awareness in relations to the test designers’ own conceptions—highlighted how the gender order where women are subordinated men becomes visible in the national tests as a consequence of the test designers internalized conceptions. The second facet—Gender awareness in relation to chemistry—discussed the hierarchy between discourses within chemistry. The third facet—Gender awareness in relation to students—problematized chemistry in relation to the students’ identity formation. In summary, I suggest that the different discourses can open up new ways to interpret chemistry and perhaps dismantle the hegemonic chemistry discourse. 相似文献
85.
86.
Recently direct optimization of information retrieval (IR) measures has become a new trend in learning to rank. In this paper,
we propose a general framework for direct optimization of IR measures, which enjoys several theoretical advantages. The general
framework, which can be used to optimize most IR measures, addresses the task by approximating the IR measures and optimizing
the approximated surrogate functions. Theoretical analysis shows that a high approximation accuracy can be achieved by the
framework. We take average precision (AP) and normalized discounted cumulated gains (NDCG) as examples to demonstrate how
to realize the proposed framework. Experiments on benchmark datasets show that the algorithms deduced from our framework are
very effective when compared to existing methods. The empirical results also agree well with the theoretical results obtained
in the paper. 相似文献
87.
A novel floating foundation to support the NREL offshore 5 MW wind turbine was designed conceptually by combining the characteristics of barge and Spar. The main focus was structural design and hydrodynamic modelling. Based on this novel floating foundation, the hydrodynamic performance was investigated in the frequency domain and time domain by using the wave analysis software HydroD and DeepC from Det Norske Veritas. The frequency domain analysis was conducted to investigate the effects of the incident wave angle and water depth. The time-domain analysis was carried out to evaluate the response of the floating foundation under a selected operational condition. The hydrodynamic performances of this floating foundation with respect to time series and response spectra were also investigated in this study. 相似文献
88.
ZHANG Ji-gao 《浙江大学学报(A卷英文版)》2007,8(3):361-369
Particle pollution in air, also sometimes known as fine dust contamination, may cause electric contact failure. Recent research further proved that the fine particle is becoming a major disruption of the electronic connectors in signal transmission system. This paper specifies the connector contact in mobile phone application. To study the contact failure of mobile phone, a series of inspections and analytical research methods are introduced. Special features that cause the contact failure are summarized. Particle accumulation is the main problem; organic material such as lactates from sweat of the human body may act as adhesives to stick the separate particles together and make them adhere on the contact surface; chemical properties of dust cause serious local corrosion. The corrosion products may trap the particles and firmly attach on the contact surface; micro motion frequently occurs at the contact interface. Hard particle can be embedded into the surface, and soft particle could be squeezed and inserted into the contact; silicon compounds in dust play the most important role in forming high resistance regions that lead to failure; deposition of particles depends on the amount of materials, static electricity attracting force and gravity force applied on the particles. Current dust test can hardly reflect the serious contact failure. It is difficult to simulate the complexity of contact failure caused by particle contamination. Thus alternative ways of simulation experiment and improvement of contact reliability are proposed. 相似文献
89.
90.
Induction of diabetes by Streptozotocin in rats 总被引:1,自引:0,他引:1
A. Akbarzadeh D. Norouzian M. R. Mehrabi Sh. Jamshidi A. Farhangi A. Allah Verdi S. M. A. Mofidian B. Lame Rad 《Indian journal of clinical biochemistry : IJCB》2007,22(2):60-64
The objective of this study is to induce experimental diabetes mellitus by Streptozotocin in normal adult Wistar rats via
comparison of changes in body weight, consumption of food and water, volume of urine and levels of glucose, insulin and C-peptide
in serum, between normal and diabetic rats. Intra-venous injection of 60mg/kg dose of Streptozotocin in adult wistar rats,
makes pancreas swell and at last causes degeneration in Langerhans islet beta cells and induces experimental diabetes mellitus
in the 2–4 days. Induction of experimental diabetes mellitus is indeed the first step in the plan of purification of pancreatic
Langerhans islet cells of normal rats for transplanting under the testis subcutaneous of experimentally induced diabetic rats.
Streptozotocin induces one type of diabetes which is similar to diabetes mellitus with non-ketosis hyperglycemia in some animal
species. For induction of experimental diabetes in male adult rats weighted 250–300 grams (75–90 days), 60mg/kg of Streptozotocin
was injected intravenously. Three days after degeneration of beta cells, diabetes was induced in all animals. The diabetic
and normal animals were kept in the metabolic cages separately and their body weight, consumption of food and water, urine
volume, the levels of serum glucose, insulin and C-peptide quantities in all animals were measured and then these quantities
were compared. For a microscopic study of degeneration of Langerhans islet beta cells of diabetic rats, sampling from pancreas
tissue of diabetic and normal rats, staining and comparison between them, were done. Induction of diabetes with Streptozotocin
decreases Nicotinamide-adenine dinucleotide (NAD) in pancreas islet beta cells and causes histopathological effects in beta
cells which probably intermediates induction of diabetes. In this study, we used Streptozotocin for our experiments in induction
of experimental diabetes mellitus. After Induction of diabetes, consumption of food and water, volume of urine and glucose
increased in the diabetic animals in comparison with normal animals, but the weight of body and the volume of insulin and
C-peptide decreased in the diabetic animals. Sampling and staining of pancreas tissue of diabetic and normal rats showed that
the Langerhans islet beta cells of diabetic rats have been clearly degenerated. In three days, Streptozotocin makes pancreas
swell and at last causes degeneration in Langerhans islet beta cells and induces experimental diabetes. It also changes normal
metabolism in diabetic rats in comparison with normal rats. Consumption of water and food, volume of urine, serum glucose
increases in diabetic animals in comparison with normal rats but the levels of serum insulin, C-peptide and body weight decreases. 相似文献