From 'following the push of nature' to 'restoring one's proper sex'--cortisone and sex at Johns Hopkins's Pediatric Endocrinology Clinic

In 1955, a paradigm shift in the conception of sex is said to have taken place, when psychologist John Money at Johns Hopkins's Pediatric Endocrinology Clinic argued that 'hermaphroditic' children could be assigned a sex contradictory to their biological sex. Rather than being born male or female, he claimed, these children learned to be boys or girls. Money was subsequently credited the invention of the term gender role. However, Money only confirmed a practice that was established at the clinic several years before his intervention. The clinic's director Lawson Wilkins (1894-1963) had already recommended that certain children, virilized by congenital adrenal hyperplasia, should be raised in the male sex, even though they were by all medical standards of the time female. What mattered for him was assigning the sex that seemed 'better' for these children. What constituted the 'better sex' was contingent on the child's psyche and habitus, social expectations, and on the range of medical and surgical interventions available at the time.     

科学与搜寻罪犯

现代科学在许多方面应用于解决犯罪问题。其范围包括血迹的实验室检验, 指纹的分类与搜寻,以及犯罪调查系统的计算机坐阵指挥。作者为科学在这个有趣领域的应用提供了某些例证。     

微营养素和肉品质量的关系

日粮中微营养素硒(Se)能够引起肌肉组织的生理变化,从而改变畜禽肉品的品质.本文着重阐明硒和VE在细胞膜和细胞质的抗氧化中独特应用,进而对肉品的形成和贮存过程中保持肉品的完整性起明显作用.     

The influence of upper-body pre-cooling on repeated sprint performance in moderate ambient temperatures

In this study, we examined the effects of upper-body pre-cooling before intermittent sprinting exercise in a moderate environment. Seven male and three female trained cyclists (age 26.8+/-5.5 years, body mass 68.5+/-9.5 kg, height 1.76+/-0.13 m, V O2peak 59.0+/-11.4 mL. kg(-1). min(-1); mean+/-s) performed 30 min of cycling at 50% V O2peak interspersed with a 10-s Wingate cycling sprint test at 5 min intervals. The exercise was performed in a room controlled at 22 degrees C and 40% relative humidity. In the control session, the participants rested for 30 min before exercise. In the pre-cooling session, the participants wore the upper segment of a liquid conditioning garment circulating 5 degrees C coolant until rectal temperature decreased by 0.5 degrees C. Rectal temperature at the start of exercise was significantly lower in the pre-cooling (36.5+/-0.3 degrees C) than in the control condition (37.0+/-0.5 degrees C), but this difference was reduced to a non-significant 0.4 degrees C throughout exercise. Mean skin temperature was significantly lower in the pre-cooling (30.7+/-2.3 degrees C) than in the control condition (32.5+/-1.6 degrees C) throughout exercise. Heart rate during submaximal exercise was similar between the two conditions, although peak heart rate after the Wingate sprints was significantly lower in the pre-cooling condition. With pre-cooling, mean peak power (909+/-161 W) and mean overall power output (797+/-154 W) were similar to those in the control condition (peak 921+/-163 W, mean 806+/-156 W), with no differences in the subjective ratings of perceived exertion. These results suggest that upper-body pre-cooling does not provide any benefit to intermittent sprinting exercise in a moderate environment.     

Mechanically braked Wingate powers: agreement between SRM, corrected and conventional methods of measurement

In this study, we assessed the agreement between the powers recorded during a 30 s upper-body Wingate test using three different methods. Fifty-six men completed a single test on a Monark 814E mechanically braked ergometer fitted with a Schoberer Rad Messtechnik (SRM) powermeter. A commercial software package (Wingate test kit version 2.21, Cranlea, UK) was used to calculate conventional and corrected (with accelerative forces) values of power based on a resistive load (5% body mass) and flywheel velocity. The SRM calculated powers based on torque (measured at the crank arm) and crank rate. Values for peak 1 and 5 s power and mean 30 s power were measured. No significant differences (P >0.05) were found between the three methods for 30 s power values. However, the corrected values for peak 1 and 5 s power were 36 and 23% higher (P <0.05) respectively than those for the conventional method, and 27 and 16% higher (P <0.05) respectively than those for the SRM method. The conventional and SRM values for peak 1 and 5 s power were similar (P >0.05). Power values recorded using each method were influenced by sample time (P <0.05). Our results suggest that these three measures of power are similar when sampled over 30 s, but discrepancies occur when the sample time is reduced to either 1 or 5 s.     

Evaluation of distance learning delivery of health information management and health informatics programmes: a UK perspective

The aim of the article is to review evaluations of distance learning programmes in health information management, in order to identify the critical success factors for such programmes and discuss future directions. The emphasis is on the UK experience, based partly on reflections on the experience of one programme at University of Wales Aberystwyth (now over 10 years old), and partly on a policy review conducted for the NHS Information Authority and the NHS Information Policy Unit. The methods are, as far as possible, those of a systematic review of existing research, with, additionally, an overview of relevant policy developments for lifelong learning. The topics covered include the aims, objectives and educational philosophies of the programmes. The evidence, combined with the UWA experience, indicates the importance of face-to-face interaction, to complement distance or virtual learning. A student-centred approach to curriculum design and delivery is essential.