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101.
The present study investigated the effect of an antianxiety drug, buspirone on blood glucose and plasma insulin level concerning
the role of 5-HT1A receptors in blood glucose regulation in healthy humans. Twelve healthy male volunteers were administered single oral doses
of buspirone (10 mg) or placebo, in a randomized, crossover way, followed by oral glucose load (75 gm in 200 ml) at reported
Tmax i.e. the time of peak plasma concentration of the respective administered drug. The blood samples were collected as predose,
postdose and post oral glucose load at 0.5, 1.0, 1.5, 2.0, 2.5 and 3.0 hr to investigate the effect of buspirone or placebo
at basal blood glucose and plasma insulin level and after oral glucose load induced (postprandial) blood glucose and plasma
insulin level. Blood glucose and plasma insulin concentrations were estimated by glucose hexokinase method and enzyme linked
immunosorbent assay (ELISA) method respectively. The concentration of blood glucose was significantly (p<0.05) decreased after
oral glucose load following administration of buspirone in comparison with placebo however no significant change was observed
in the fasting blood glucose and plasma insulin (fasting and oral glucose load induced) level. In conclusions, the present
study findings show that buspirone produced a significant alteration in blood glucose level in healthy humans. In addition,
study results also indicate that the involvement of serotonergic (5-HT, receptors) mechanism of blood glucose regulation in
humans is different from animals. 相似文献
102.
A. K. Pendse Rajbaia Kavita Sharma Asha Mehta P. P. Singh C. Bordia 《Indian journal of clinical biochemistry : IJCB》1994,9(2):91-95
Jhamarkotra is located a distance of 25 kms from Udaipur city. It has richest deposits of phosphorite ore (Rock phosphate) in our country. The mine has been under operation for the last several years. However, the effect of environmental influence have not been investigated. In the present study water analysis from 8 points of delivery in mine area along with pathological and biochemical parameters is reported. The water is relatively hard and has significantly high content of fluoride and chloride. The miners were divided into four groups on the basis of their exposure in the mining area. The group were; a) non exposed, b) indirectly exposed, c) transiently exposed and d) directly exposed. These were compared with controls. The results indicate that serum uric acid, GPT, alkaline phosphatase level were elevated in directly exposed miners. 相似文献
103.
The paper examined whether in-service teachers from Australia to Italy differ in terms of their attitudes, concerns, efficacy beliefs and intentions to include learners with disabilities in their classrooms. An attempt was also made to determine predictors of the participants’ intentions to include learners with disabilities in their classrooms. Participants for the study consisted of 153 Australian and 156 Italian in-service teachers. Results revealed that Italian teachers had significantly more positive attitudes, lower degree of concerns and higher level of intentions to implement inclusion in their classrooms. In both countries, attitudes and efficacy emerged as significant predictors of participants’ intentions to include learners with disabilities in regular classrooms. Reasons that could explain differences in the teachers’ beliefs from the two countries are explained using historical-cultural and legal frameworks prevalent in Australia and Italy. Implications of the findings for policy-makers, university teachers and researchers are presented that may have relevance in guiding the implementation of inclusive education in Australia, Italy and beyond. 相似文献
104.
Garima Sharma 《Compare》2019,49(3):358-374
Current literature on parent aspirations has not empirically explored the factors that may lead to differences in aspirations among similar types of parents. Additionally, little is known about the gendered nature of these differences. In this study, we seek to understand factors shaping mothers’ aspirations in regards to education, marriage, and careers of their daughters and sons, and to explore why differences may be found for mothers from similar socioeconomic backgrounds. Using a case study approach, we conduct in-depth interviews with 28 mothers in the Indian town of Forbesganj, Bihar. We use a conceptual framework based on the capabilities approach, and draw on theories of social learning, or learning from one’s peers, through which to understand differences in aspirations. Findings suggest that mothers desire lives for their children that are different from their own, and that conceptions of such lives are influenced by exposure to role models in their communities. 相似文献
105.
Ebbeck Marjory Yim Hoi Yin Bonnie Ho Siew Yin Sharma Minushree 《Early Childhood Education Journal》2022,50(2):291-300
Early Childhood Education Journal - Child care centres in many developed countries have expanded exponentially due to the increased participation of women in the workforce. Consequently, children... 相似文献
106.
Sharma Sunny Rana Vijay Malhotra Manisha 《Education and Information Technologies》2022,27(2):1523-1538
Education and Information Technologies - Web recommendation systems are ubiquitous in the world used to overcome the product overload on e-commerce websites. Among various filtering algorithms,... 相似文献
107.
Kumar Bimal Aklesh Sharma Bibhya Nakagawa Elisa Yumi 《Education and Information Technologies》2022,27(3):3723-3741
Education and Information Technologies - Context-aware mobile learning applications provide learning materials to suit the needs of individual learners. Despite several applications developed,... 相似文献
108.
Cultural Studies of Science Education - Education reforms are rarely successful or free of controversies. However, efforts to STEM-ify public education in the USA by positioning education in STEM... 相似文献
109.
Over the series of articles on circadian rhythms, we saw that living organisms exhibit daily rhythms in multiple behaviours and physiological processes. Although some rhythms may be passive responses to 24 h environmental cycles, many are regulated by endogenous-rhythmgenerating machinery called circadian clocks. We have introduced the concept of circadian clocks, their organization and the underlying molecular mechanisms. In this article, we will dwell upon one of the most fundamental questions pertaining to circadian clocks, ‘Why do we have them?’. The aim of this article is not to provide answers, but to discuss the efforts and strategies used to address this question and critically evaluate explanations proposed till date. 相似文献
110.
This is a survey of MBA students'preparedness for launching new businessinitiatives or other entrepreneurialactivities. It explores the readiness of theMBA students, estimated on dimensionscomprising knowledge, attitude, skills,experience, opportunity and networks. Thevariation of the postgraduate students'perceptions along these six dimensions andcertain demographic factors, including gender,stage of the MBA programme, students' permanentresidence, their funding source, enrolmentstatus, employment status, marital status andyears of work experience, was considered. Multiple regressions then established therelationship between entrepreneurialpreparedness and the six dimensions. Finally,some broad implications for the MBA curriculumare considered. 相似文献