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The Elementary Science Integration Project (ESIP) brought together teachers knowledgeable about, and committed to, whole-language instruction with their science-oriented counterparts to explore connections between the disciplines and build from teachers' strengths. By recognizing commonalities, that both hands-on science and whole language center on inquiry and focus on children's learning processes, ESIP was designed to reveal the issues both groups of teachers see as important as they go about making classroom decisions. The ultimate goal of the project was to promote science as central to cross-curricular study, thus increasing the comfort level of teachers, the amount of time devoted to science in the classroom, and an interest in inquiry. This article described the project and identified the considerations teachers used to evaluate science–language-arts connections. Twenty expert and 7 novice teachers worked together over a 2-year period to construct and elaborate their own understandings of curricular integrátion, designing action research projects to explore their newfound understandings. Teachers kept journals and participated in extensive group discussions and interviews that provided the data sources for this article. Results revealed the influence of teachers' scholarly and pedagogical orientations on the way they think about science–language-arts connections and the influence of personal experiences in convincing teachers that science–language-arts connections are worth fostering in the classroom.  相似文献   
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We report the Laser Induced Forward Transfer (LIFT) of antibodies from a liquid donor film onto paper receivers for application as point-of-care diagnostic sensors. To minimise the loss of functionality of the active biomolecules during transfer, a dynamic release layer was employed to shield the biomaterial from direct exposure to the pulsed laser source. Cellulose paper was chosen as the ideal receiver because of its inherent bio-compatibility, liquid transport properties, wide availability and low cost, all of which make it an efficient and suitable platform for point-of-care diagnostic sensors. Both enzyme-tagged and untagged IgG antibodies were LIFT-printed and their functionality was confirmed via a colorimetric enzyme-linked immunosorbent assay. Localisation of the printed antibodies was exhibited, which can allow the creation of complex 2-d patterns such as QR codes or letters for use in a final working device. Finally, a calibration curve was determined that related the intensity of the colour obtained to the concentration of active antibodies to enable quantitative assessment of the device performance. The motivation for this work was to implement a laser-based procedure for manufacturing low-cost, point-of-care diagnostic devices on paper.  相似文献   
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Mentoring involves the use of an experienced individual to teach and train someone with less knowledge in a given area. Through individualized attention the mentor/teacher transfers needed information, feedback, and encouragement to the protegé/learner. The success of such a program depends heavily on the investment of effort by the mentor. Although benefits for the protegé are typically easily discerned and have been well documented in the past, the factors affecting motivation for the mentor have been less well defined. Therefore, after a discussion of the basic mentoring process and a summary of the protegé and organizational benefits, the major focus of our paper is directed to the extrinsic and intrinsic rewards attained by those who participate as mentors and to the establishment of guidelines that help to maximize the value for all involved.  相似文献   
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