Reading Progress Monitoring for Secondary‐School Students: Reliability,Validity, and Sensitivity to Growth of Reading‐Aloud and Maze‐Selection Measures

The validity and reliability of curriculum‐based measures in reading as indicators of performance and progress for secondary‐school students were examined. Thirty‐five grade 8 students completed reading aloud and maze‐selection measures weekly for 10 weeks. Criterion measures were the state standards test in reading and the Woodcock–Johnson III Test of Achievement. Different time frames for each measure were compared. Most alternate‐form reliability coefficients were above .80. Criterion‐related validity coefficients ranged from .77 to .89. No differences related to time were found. Only maze selection reflected significant growth, with an average increase of 1.29 correct choices per week. Maze growth was related to the reading performance level and to change on the Woodcock–Johnson III from pre‐ to posttest.     

Multilingual modeling of cross-lingual spelling variants

Technical term translations are important for cross-lingual information retrieval. In many languages, new technical terms have a common origin rendered with different spelling of the underlying sounds, also known as cross-lingual spelling variants (CLSV). To find the best CLSV in a text database index, we contribute a formulation of the problem in a probabilistic framework, and implement this with an instance of the general edit distance using weighted finite-state transducers. Some training data is required when estimating the costs for the general edit distance. We demonstrate that after some basic training our new multilingual model is robust and requires little or no adaptation for covering additional languages, as the model takes advantage of language independent transliteration patterns. We train the model with medical terms in seven languages and test it with terms from varied domains in six languages. Two test languages are not in the training data. Against a large text database index, we achieve 64–78 % precision at the point of 100% recall. This is a relative improvement of 22% on the simple edit distance.     

Buddhist Wall Paintings at Nako Monastery,North India: Changing of the Technology Throughout Centuries

The technical study of wall paintings from the Buddhist temple complex at Nako, Western Himalayas, was one of the basic preconditions required for designing an appropriate conservation strategy. The complex, composed of four temples from the eleventh–twelfth century, offered a unique possibility to carry out a comprehensive research of technology and painting materials used in early and later western Tibetan Buddhist wall paintings as well as a comparative assessment with murals from other sites in the Western Himalayas. The study was based on extensive fieldwork and an integrated analytical approach comprising a wide range of non-destructive and micro-destructive methods. Answering the question of the coevality of paintings in the smaller temples with other original murals, the precise characterisation of binding media, the detection of the yellow dye gamboge and natural minerals posnjakite and brochantite identified for the first time in Himalayan murals, the clarification of technology of metal decoration, and the making of raised elements are some of the most exciting results which emerged from the research.     

Effects of purposeful soccer heading on circulating small extracellular vesicle concentration and cargo

BackgroundConsidering the potential cumulative effects of repetitive head impact (HI) exposure, we need sensitive biomarkers to track short- and long-term effects. Circulating small extracellular vesicles (sEVs) (<200 nm) traffic biological molecules throughout the body and may have diagnostic value as biomarkers for disease. The purpose of this study was to identify the microRNA (miRNA) profile in circulating sEVs derived from human plasma following repetitive HI exposure.MethodsHealthy adult (aged 18–35 years) soccer players were randomly assigned to one of 3 groups: the HI group performed 10 standing headers, the leg impact group performed 10 soccer ball trapping maneuvers over 10 min, and the control group did not participate in any soccer drills. Plasma was collected before testing and 24 h afterward, and sEVs were isolated and characterized via nanoparticle tracking analysis. Next-generation sequencing was utilized to identify candidate miRNAs isolated from sEVs, and candidate microRNAs were analyzed via quantitative polymerase chain reaction. In silico target prediction was performed using TargetScan (Version 7.0; targetscan.org) and miRWalk (http://mirwalk.umm.uni-heidelberg.de/) programs, and target validation was performed using luciferase reporter vectors with a miR-7844-5p mimic in human embryonic kidney (HEK) 293T/17 cells.ResultsPlasma sEV concentration and size were not affected across time and group following repetitive HI exposure. After 24 h, the HI read count from next-generation sequencing showed a 4-fold or greater increase in miR-92b-5p, miR-423-5p, and miR-24-3p and a 3-fold or greater decrease in miR-7844-5p, miR-144-5p, miR-221-5p, and miR-22-3p. Analysis of quantitative polymerase chain reaction revealed that leg impact did not alter the candidate miRNA levels. To our knowledge, miR-7844-5p is a previously unknown miRNA. We identified 8 miR-7844-5p mRNA targets: protein phosphatase 1 regulatory inhibitor subunit 1B (PPP1R1B), LIM and senescent cell antigen-like domains 1 (LIMS1), autophagy-related 12 (ATG12), microtubule-associated protein 1 light chain 3 beta (MAP1LC3B), integrin subunit alpha-1 (ITGA1), mitogen-activated protein kinase 1 (MAPK1), glycogen synthase kinase 3β (GSK3β), and mitogen-activated protein kinase 8 (MAPK8).ConclusionCollectively, these data indicate repetitive HI exposure alters plasma sEV miRNA content, but not sEV size or number. Furthermore, for the first time we demonstrate that previously unknown miR-7844-5p targets mRNAs known to be involved in mitochondrial apoptosis, autophagy regulation, mood disorders, and neurodegenerative disease.     

Assessing working students' college experiences: a grounded theory approach

This study explores working students' college experiences using the grounded theory approach. Focus groups were conducted to allow working students to elaborate on their college experiences, clarifying issues not easily addressed through surveys. Two theoretical propositions are offered to describe how working students are constantly searching for meaningful work as well as meaning in their work. It is important for institutions to consider work as an educationally purposeful activity outside classroom and to create job opportunities that benefit students academically, socially and financially.