Anti-adipogenic effects of extracts of Ficus deltoidea var. deltoidea and var. angustifolia on 3T3-L1 adipocytes简

Objective

This study examined the anti-adipogenic effects of extracts of Ficus deltoidea var. deltoidia and var. angustifolia, a natural slimming aid, on 3T3-L1 adipocytes.

Methods

Methanol and water extracts of leaves of the F. deltoidea varieties were analyzed to determine their total flavonoid content (TFC) and total phenolic content (TPC), respectively. The study was initiated by determining the maximum non-toxic dose (MNTD) of the methanol and water extracts for 3T3-L1 preadipocytes. Possible anti-adipogenic effects were then examined by treating 2-d post confluent 3T3-L1 preadipocytes with either methanol extract or water extract at MNTD and half MNTD (1/2MNTD), after which the preadipocytces were induced to form mature adipocytes. Visualisation and quantification of lipid content in mature adipocytes were carried out through oil red O staining and measurement of optical density (OD) at 520 nm, respectively.

Results

The TFCs of the methanol extracts were 1.36 and 1.97 g quercetin equivalents (QE)/100 g dry weight (DW), while the TPCs of the water extracts were 5.61 and 2.73 g gallic acid equivalents (GAE)/100 g DW for var. deltoidea and var. angustilofia, respectively. The MNTDs determined for methanol and water extracts were (300.0±28.3) and (225.0±21.2) μg/ml, respectively, for var. deltoidea, while much lower MNTDs [(60.0±2.0) μg/ml for methanol extracts and (8.0±1.0) μg/ml for water extracts] were recorded for var. angustifolia. Studies revealed that the methanol extracts of both varieties and the water extracts of var. angustifolia at either MNTD or 1/2MNTD significantly inhibited the maturation of preadipocytes. Conclusions: The inhibition of the formation of mature adipocytes indicated that leaf extracts of F. deltoidea could have potential anti-obesity effects.     

Deparochializing Education: Globalization,regionalization, and the formation of an ASEAN education space1

Research on the Association of Southeast Asian Nations (ASEAN) has hitherto attracted scholarly attention and debate by both regional and international scholars working in area studies, such as international relations and Asia-Pacific/Southeast Asia studies. Confined to area studies, scholarly research on ASEAN is limiting because the parameters of research are invariably locked into issues related to economics, politics, security, and trade development in and around the region. Notably, education has been an under-researched topic. On the cusp of its 40th anniversary ASEAN envisages the formation of an ASEAN identity and socio-cultural community. As a point of departure from area studies, this paper engages in “regionalist thinking” about ASEAN, education and identity making. This “regionalist thinking” is, however, only thinkable and imaginable with reference to the “global,” because as a region ASEAN, whether perceived in geographical or in spatial terms, is part of the global sphere in which it is embedded. I argue in this paper that while historically education and schooling are directly related to the imaginaries of nation building and national identity making, the call for the creation of an ASEAN identity and the formation of a socio-cultural community requires that nation states in the region deparochialize education and redesign pedagogies that “teach and learn beyond the nation.”     

CHELLO: The Child/Home Environmental Language and Literacy Observation

The purpose of this study was to develop a valid and reliable tool for measuring the quality of the language and literacy environment in home-based settings. Based on a convergence of research on the ecological and psychological factors associated with early literacy development, the Child/Home Environmental Language and Literacy Observation (CHELLO) was developed to gauge the quality of current practices associated with positive early childhood literacy outcomes. Following the structure of the Early Language and Literacy Classroom Observation Scale (ELLCO) [Smith, M., & Dickinson, D. (2002). Early language & literacy classroom observation. Baltimore, MD: Brookes], we developed two interdependent tools: The Literacy Environment Checklist and the Group/Family Observation and Provider Interview. Inter-rater reliability using weighted kappas indicated acceptable reliability. Following this analysis, the CHELLO was administered in 128 home-based settings in four low-income urban areas. Initial evidence of its psychometric properties provided support for internal consistency. Although more research is needed, the CHELLO has the potential to serve as a useful tool for examining the language and literacy environment in home-based settings.     

Models of English and Chinese word reading for adolescent Chinese–English bilinguals

These two studies examined the processes underlying English and Chinese word reading in Chinese–English bilinguals in relation to their experiences with their second language (L2), as determined by length of time in an English-speaking environment. Phonological awareness, morphological awareness and vocabulary measures were administered in English and Chinese to adolescents and young adults living in Canada. The results show that similar word reading processes were used to read English and Chinese for the bilinguals who were recent immigrants and had less exposure to English. Specifically, vocabulary knowledge was directly related to English and Chinese word reading in the more recent immigrants. However, phonological awareness was not related to English word reading in this group. Conversely, reading processes in the two languages were less similar for participants who were long-term immigrants. In the long-term immigrant group, English reading was related to phonological awareness. The writing system of the first language (L1) exerted an influence on L2 reading and the degree of influence was related to language experience.     

Creating thinking schools through authentic assessment: the case in Singapore

Using Singapore as an example, we argue that schools need to equip and encourage teachers to adopt authentic assessment in teaching and learning so as to develop the students’ higher-order thinking. The importance of teaching and assessing higher-order thinking in Singapore classrooms is encapsulated in the vision of ‘Thinking Schools’ launched by the Ministry of Education in 1997. Underpinning this vision is a shift from conventional assessment to authentic assessment. Unlike conventional paper-and-pencil tests that focus on knowledge reproduction and low-level cognitive processing skills in artificial, contrived contexts, authentic assessment tasks underscore knowledge construction, complex thinking, elaborated communication, collaboration and problem solving in authentic contexts. However, the creation of thinking schools in Singapore remains a constant challenge as many teachers tend to rely on conventional assessment and are often ill-prepared to implement authentic assessment. By presenting the findings from a recent empirical study, we propose that schools build teacher capacity by providing ongoing and sustained professional development on authentic assessment for teachers.     

Assessing motivational styles of students in the south-east Asian context of Singapore

High levels of academic achievement in Asian educational systems have generated interest in the study of motivational patterns of students in these contexts. The objectives of this paper are firstly, to provide a review of existing literature on the study of motivational styles amongst students and secondly, to identify the occurrence of different motivational styles amongst students in Singapore,. The method of identifying different motivational styles was adapted from a procedure first developed by Craske (1988). The findings of this study indicate that although the distribution of motivational styles amongst the Singaporean students was consistent with that as obtained by Craske, there was a higher tendency for maladaptive motivation amongst the males than the females. In contrast, Craske found no gender differentiation, though earlier researchers had found that maladaptive motivation was more common among the females.     

The Family Festival Prevention Model: findings from a pilot of a teenage pregnancy prevention programme conceptualised by and for Mexican American communities

Despite an overall reduction in teenage pregnancy rates in the USA, the decrease for young women of Mexican heritage in the USA has been less significant than the decrease for their White and African-American peers. Furthermore, the availability of teenage pregnancy prevention models that are conceptualised specifically for people of Mexican descent is minimal. Using qualitative focus group data that were triangulated against quantitative survey data and collected from 35 young people and their parents, this paper presents findings from the pilot of a teenage pregnancy prevention model designed for and with input from Mexican American young women and men and their parents. Reflecting a favourable and impactful experience for the participants, the findings present implications for future intervention efforts and research.     

Building student employability through interdisciplinary collaboration: an Australian Case Study

Abstract

Given that graduate employment is a clear outcome of education success, there is an urgent need to conceptualize course design strategically to maximize students’ chances of employment. In this paper, we present an Australian case study in which we used a structured career information literacy learning approach to build employability in a biological sciences capstone course, through collaboration between the university library, academics, and career service. We report the context, method, measurement, outcomes of collaboration, and roles of contributors in this partnership. This case study lends itself to potential ways of incorporating career information literacy into an academic context.     

The effect of a fast bowling harness in cricket: an intervention study

The influence of a bowling harness, as a training aid, was assessed as a means of modifying bowling technique. Thirty-three 13-year-old bowlers received a standardized 15 min of bowling coaching twice a week for 8 weeks. They were randomly assigned to one of two groups. The 13 participants in the intervention group used the bowling harness throughout the coaching, while also receiving verbal and visual feedback. The 20 participants in the non-harness group received the same visual and verbal feedback. Three-dimensional videography (200 Hz) of each player's bowling action enabled the calculation of transverse plane shoulder alignment counter-rotation, separation angle, lateral flexion and hyperextension of the trunk before and after the intervention. The restriction applied by the harness produced a significant reduction ( P = 0.006) in separation angle and forced the bowler to adopt a position at back-foot impact that reduced the 'twist' in the spine. However, it had no effect on restricting other aspects of trunk movement during the critical phases of the bowling action. No significant long-term modifications to technique were found after the coaching intervention when players were assessed without the harness.