共同的语言,相隔千里

有时候,我在RSS浏览器里,总能读到一系列博客文章,看似不相关,却提出了一种新的观点。不管称它们是偶然发现、群体意识或是机缘巧合,这些文章提出的观点却是我在RSS看新闻时最棒的收获之一。     

Marketing as Matching

This paper explores the concept of matching the activities of higher education institutions to the needs of a wider society. The author recognises that universities and polytechnics have absolute loyalties beyond the market-place. Nevertheless, now as never before there is an environment in which mututally advantageous relationships between higher education and the world of industry can be developed.     

Thermally multiplexed polymerase chain reaction

Amplification of multiple unique genetic targets using the polymerase chain reaction (PCR) is commonly required in molecular biology laboratories. Such reactions are typically performed either serially or by multiplex PCR. Serial reactions are time consuming, and multiplex PCR, while powerful and widely used, can be prone to amplification bias, PCR drift, and primer-primer interactions. We present a new thermocycling method, termed thermal multiplexing, in which a single heat source is uniformly distributed and selectively modulated for independent temperature control of an array of PCR reactions. Thermal multiplexing allows amplification of multiple targets simultaneously—each reaction segregated and performed at optimal conditions. We demonstrate the method using a microfluidic system consisting of an infrared laser thermocycler, a polymer microchip featuring 1 μl, oil-encapsulated reactions, and closed-loop pulse-width modulation control. Heat transfer modeling is used to characterize thermal performance limitations of the system. We validate the model and perform two reactions simultaneously with widely varying annealing temperatures (48 °C and 68 °C), demonstrating excellent amplification. In addition, to demonstrate microfluidic infrared PCR using clinical specimens, we successfully amplified and detected both influenza A and B from human nasopharyngeal swabs. Thermal multiplexing is scalable and applicable to challenges such as pathogen detection where patients presenting non-specific symptoms need to be efficiently screened across a viral or bacterial panel.     

Maternal Unresponsiveness and Child Disruptive Problems: The Interplay of Uninhibited Temperament and Dopamine Transporter Genes

This study examined how and why dopamine transporter (DAT1) susceptibility alleles moderate the relation between maternal unresponsiveness and young children's behavior problems in a disadvantaged, predominantly minority sample of 201 two‐year‐old children and their mothers. Using a multimethod, multisource design, the findings indicated that a genetic composite of DAT1 susceptibility alleles (rs27072, rs40184) potentiated associations between maternal unresponsive caregiving and increases in children's behavior problems 2 years later. Moderator‐mediated‐moderation analyses further revealed that the DAT1 diathesis was more proximally mediated by the potentiating effects of children's uninhibited temperament in the pathway between maternal unresponsiveness and disruptive behavior problems. Results are interpreted in the context of supporting and advancing the biosocial developmental model (Beauchaine & Gatzke‐Kopp, 2012).     

Examining the Legacy of Urban Catholic Schooling in the U.S.: A Systematic Literature Review

The Urban Review - Research conducted in the twentieth century found urban Catholic schools in the U.S. had a legacy of providing high quality educational opportunities for low-income students and...     

Understanding heterogeneity in pathways between interparental conflict and children's involvement: The moderating role of affect-biased attention

The study examined the moderating role of children's affect-biased attention to angry, fearful, and sad adult faces in the link between interparental conflict and children's distinct forms of involvement. Participants included 243 preschool children (M_age = 4.60 years, 56% female) and their parents from racially (48% African American, 43% White) and socioeconomically (median annual household income = $36,000) diverse backgrounds. Data collection took place in the Northeastern United States (2010–2014). Utilizing a multi-method, multi-informant, longitudinal design, attention away from anger selectively amplified the link between interparental conflict and children's subsequent coercive involvement (β = −.15). Greater attention to fear potentiated the pathway between interparental conflict and children's later cautious (β = .14) and caregiving involvement (β = .15). Findings are interpreted in the context of environmental sensitivity models.     

Open access to data: An ideal professed but not practised

Data-sharing is an essential tool for replication, validation and extension of empirical results. Using a hand-collected data set describing the data-sharing behaviour of 488 randomly selected empirical researchers, we provide evidence that most researchers in economics and management do not share their data voluntarily. We derive testable hypotheses based on the theoretical literature on information-sharing and relate data-sharing to observable characteristics of researchers. We find empirical support for the hypotheses that voluntary data-sharing significantly increases with (a) academic tenure, (b) the quality of researchers, (c) the share of published articles subject to a mandatory data-disclosure policy of journals, and (d) personal attitudes towards “open science” principles. On the basis of our empirical evidence, we discuss a set of policy recommendations.