Neuro-space mapping for modeling heterojunction bipolar transistor

A neuro-space mapping(Neuro-SM) for modeling heterojunction bipolar transistor(HBT) is presented, which can automatically modify the input signals of the given model by neural network. The novel Neuro-SM formulations for DC and small-signal simulation are proposed to obtain the mapping network. Simulation results show that the errors between Neuro-SM models and the accurate data are less than 1%, demonstrating that the accurcy of the proposed method is higher than those of the existing models.     

Cloning and efficient expression of <Emphasis Type="Italic">Bacillus sp.</Emphasis> BH072 <Emphasis Type="Italic">tasA</Emphasis> gene in <Emphasis Type="Italic">Escherichia coli</Emphasis>

The Bacillus strain BH072 isolated from a honey sample showed strong antifungal activity against phytopathogen. Gene cloning test demonstrated that the strain had a tasA gene encoding an antifungal TasA protein. Although the wild strain simultaneously produced various antifungal substances, only the physicochemical property and antifungal activity of TasA protein were unclear due to the difficulty in extraction. In this study, tasA gene encoding the protein from Bacillus sp. BH072 was amplified by using the polymerase chain reaction (PCR) method and cloned into pET 28a (+) vector, and then expressed in host cells Escherichia coli BL21 (DE3). The expressed proteins were collected by centrifugation and ultrasonic treatment, and then purified by using nickel-nitrilotriacetic acid (Ni-NTA) metal affinity column and dialysis methods. The result of sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) test showed that an expected protein band appeared with a size of 31 kDa. The expressed products possessed antifungal activity against the phytopathogenic indicator strain Botrytis cinerea. A genetically engineered strain tasA of E. coli was established in this study which can efficiently express Tas A protein.     

学习科学：推动教育的深层变革

当前教育信息化蓬勃发展,在备受赞赏的同时也屡被质疑。至于原因,恐怕还是“人究竟是怎么学习的,怎样才能促进有效学习？”这一根本性问题依然未得到彻底解决。该文从教育信息化的发展现状谈起,剖析目前存在的问题及解决方法,然后仔细梳理了学习科学的发生、发展和研究现状,指出脑科学与学习、基于大数据的学习分析和技术增强的学习等学习科学研究将有助于推动教育从更深的层面发生变革。     

Culturally Responsive Counseling for Asian Americans: Clinician Perspectives

Research has consistently found acute mental health treatment disparities among Asian Americans. One proposed reason for the underutilization of mental health services by Asian Americans is that available services are not culturally competent. This exploratory study presents qualitative data gathered from interviews with professional counselors who serve Asian American clients. Findings revealed significant barriers to counseling due to cultural stigma and shame, suppression of emotions, and communication gaps between clients and counselors. In response, clinicians frequently made adjustments to therapeutic approaches to accommodate the cultural beliefs and practices of clients and families. Implications for practice and research are discussed.     

Differential effects of reading trainings on reading processes: a comparison in Grade 2

Phonics, fluency, and reading strategy trainings are evidence-based interventions that foster the reading skills of poor readers in primary school. The purpose of the present study was to compare differential effects of the three types of trainings on the efficiency of component processes on word, sentence, and text level immediately after the training and at a 3-month follow-up. The 235 poor readers were randomly allocated to one of the reading interventions or to a control condition. All interventions consisted of 25 sessions that were scheduled twice a week and lasted 45 min. Results indicated short-term effects of the phonics training and the strategy training on the efficiency of a broad range of word-level and sentence-level processes. None of the treatment effects persisted over the long term, indicating the need for instructional efforts to regularly practice the acquired skills after the actual training.     

马克思主义"行"之谓、"行"之实与"行"之倚——从"归根到底是因为马克思主义行"说起

"归根到底是因为马克思主义行"这一重要论断,既是一种称谓表达与价值评判,又触及马克思主义的本质内涵与品质特征,还关涉中国共产党的主体作为与践行方式,分别构成马克思主义"行"之谓、"行"之实、"行"之倚。从"行"之谓到"行"之实,从"行"之实到"行"之倚,如一个链条那样相互衔接,将马克思主义由内至外、由对象性存在到主导性力量,由可以"行"到能够"行"、由"行"之根据到"行"之实现,一一展示出来,构成一幅马克思主义"行"的逻辑运行图景。"行"之谓是总结性概括、提炼性结论,"行"之实是内在性根据、根本性支撑,"行"之倚是关键性因素、决定性环节,三个层面共同诠释了"归根到底是因为马克思主义行"的要义与真谛。     

基于CGE模型的水资源政策模拟分析简

全面建设节水型社会,实现水资源的高效利用、合理配置和可持续发展是21世纪中国国家发展的重要战略。调整水资源要素水价、削减生产用水补贴和促进用水技术进步是实现有效节水的对策。基于水资源同时以水要素和水商品形式存在的特点和我国水资源报酬征收的实际情况,本文建立了包含水生产与供应业、水资源要素报酬、生产用水补贴的水资源可计算一般均衡模型（CGE）;建立了提高水资源要素价格、调整生产用水补贴和技术进步3种情景;以江西省为例,编制SAM表并利用CGE模型模拟各情景对经济和社会的影响,并且对同一节水目标下3种情景的模拟结果进行比较分析。研究结果表明：提高水资源要素价格、削减生产用水补贴和技术进步都能促进用水效率提高,减少总用水需求量;但无论从总产出、GDP、就业、物价水平还是居民及企业收入等指标看,前两种情景会对经济产生负面影响,且削减生产用水补贴的负面影响更大,技术进步则在达到节水目标的同时能够促进经济发展;3种情景变化对农业的产出和用水量影响显著,说明农业节水潜力巨大。进行政策选择时应该慎重考虑各种政策的影响和政策的可操作性,将农业作为重点节水行业,并长期大力推广节水技术。     

Comparison of digoxin concentration in plastic serum tubes with clot activator and heparinized plasma tubes

Introduction:

Sample type recommended by the manufacturer for the digoxin Abbott assay is either serum collected in glass tubes or plasma (sodium heparin, lithium heparin, citrate, EDTA or oxalate as anticoagulant) collected in plastic tubes. In our hospital samples are collected in plastic tubes. Our hypothesis was that the serum sample collected in plastic serum tube can be used interchangeably with plasma sample for measurement of digoxin concentration. Our aim was verification of plastic serum tubes for determination of digoxin concentration.

Materials and methods:

Concentration of digoxin was determined simultaneously in 26 venous blood plasma (plastic Vacuette, LH Lithium heparin) and serum (plastic Vacuette, Z Serum Clot activator; both Greiner Bio-One GmbH, Kremsmünster, Austria) samples, on Abbott AxSYM analyzer using the original Abbott Digoxin III assay (Abbott, Wiesbaden, Germany). Tube comparability was assessed using the Passing Bablok regression and Bland-Altman plot.

Results:

Serum and plasma digoxin concentrations are comparable. Passing Bablok intercept (0.08 [95% CI = −0.10 to 0.20]) and slope (0.99 [95% CI = 0.92 to 1.11]) showed there is no constant or proportional error.

Conclusion:

Blood samples drawn in plastic serum tubes and plastic plasma tubes can be interchangeably used for determination of digoxin concentration.     

Social capital as a driver of local knowledge exchange: a social network analysis

The objective of this paper is to take an in-depth look, from a network perspective, at the role that social capital plays in improving knowledge exchange between organizations. To do this, we consider the three dimensions of social capital: the structural dimension, as measured by the position of firms bridging structural holes; the relational dimension, as gauged by the level of trust and friendship in each relationship; and the cognitive dimension, as estimated by the presence of a shared culture. We also evaluate the level of organizational and human capital present in terms of the firms in the network. Empirical evidence has been gathered from the Madrid Science Park in Spain by applying the social network analysis methodology. The results show that the three dimensions of social capital play a significant role in increasing knowledge exchange in this network, while human and organizational capital differences are only significant for a sub-sample.     

Freelancers and the absorption of external knowledge: practical implications and theoretical contributions

The term absorptive capacity (AC) describes the process of utilising external knowledge. Although firms are becoming increasingly reliant on highly skilled freelancers as a source of external knowledge, the literature on AC has not incorporated this collaboration for freelancers. In this paper, we address this research deficit in two ways: First, we argue that the ability to collaborate effectively and efficiently with freelancers plays a crucial role in the process of absorbing external knowledge. Second, we argue that the example of freelancers challenges researchers to rethink the conceptualisation of organisational boundaries within the concept of AC. Our paper is based upon previous theoretical insights and exploratory empirical data from a research project on German IT freelancers. For the practice of knowledge management, our paper elaborates upon how organisations can enhance their AC by investing in practices and routines that contribute to successful collaboration with freelancers.