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Essential hypertension (EH) is a multifactorial and complex disease with high rate of incidence and associated co-morbidities. Previous studies do not provide unanimous results for the risk of hypertension and association with Fok I genotype frequency and serum vitamin D levels. Hence, this study was undertaken to determine the status of Fok I vitamin D receptor (VDR) gene polymorphism along with vitamin D levels and blood pressure in patients with EH. Four hundred (200 controls and 200 cases of essential hypertension) participants from general Indian population were enrolled in this study. Peripheral blood samples were collected for genotyping Fok I-VDR gene polymorphism using PCR–RFLP method whereas 25-OH vitamin D levels in serum were quantified using high performance liquid chromatography (HPLC). Significantly reduced 25-OH vitamin D levels were observed in patients with EH (24.04 ± 8.62 vs 50.46 ± 15.46) compared to control subjects (p = 0.0001). Homozygous recessive genotype ‘ff’ frequency was increased by 8.06 fold (CI: 3.71–17.47, p = 0.0001) in patients with EH compared to dominant ‘FF’ genotype frequency. In conclusion, recessive ‘ff’ genotype frequency correlates with reduced serum vitamin D levels and results in significantly increased systolic and diastolic blood pressures leading to predisposition of EH.  相似文献   
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Abstract

The limited effectiveness and fiscal unsustainability of professional-led public sector extension systems in developing countries have aroused considerable interest in Farmer-led Extension (FLE) approaches in the recent decades. A key challenge facing these initiatives is a lack of sustainability of the farmer groups developed through project or programme assistance. This not only makes FLE initiatives costly, but also creates dependency among farmers. Despite this, the knowledge of what can make externally-initiated FLE groups sustainable is scant and largely anecdotal. In this paper we provide an empirically-drawn and theoretically-informed framework to fill this knowledge gap.

The framework is based on a comparative case study of six non-sustained and four sustained FLE groups initiated through an innovative extension reform project in Bangladesh and a comparison of the results with the theories of collective action.

We have identified four sets of inter-related factors called ‘capitals’ affecting group sustainability: ‘financial capital’ accumulated through group-based microcredit activities, an effective governance mechanism called ‘institutional capital’ devised by the members themselves, good quality group leaders and facilitators called ‘human capital’, and past relations of exchange, reciprocity, trust and respect called ‘social capital’ among members and between members and professional facilitators. While microcredit can benefit sustainability, it suits women rather than men farmers. Good quality leaders and facilitators are not only technically competent, but also fair, innovative, tenacious, self-sacrificing, trustworthy, honest, and sincere. All forms of social capital are not useful for group sustainability and social capital can make a positive impact only when the other types of capital—human and institutional—are present within a group.

To improve group sustainability, FLE programmes should take a holistic approach and address the four kinds of capitals proposed in this paper. Key strategies may include: combining extension (information or advisory functions) with economic activities but avoiding a one-size-fits-all solution, recruiting group leaders and facilitators by going beyond technical considerations (e.g. taking into account the personality traits identified in this study), adopting a bottom-up approach in devising group rules and regulations, and taking into account both the positive and negative aspects of social capital.

The originality of our research lies in the explanatory framework that we provide in this paper. Our study also contributes to the intellectual debates on social capital by exhibiting the dual roles that social capital plays and its complex interrelationships with other forms of capital.  相似文献   
176.
The study is focused on finding out the level of use of on-line databases by faculty members and research scholars of the Jawaharlal Nehru University (JNU) and Jamia Millia Islamia (JMI), Delhi (India). Both are Central Universities and are funded by the University Grants Commission (UGC). A well-structured questionnaire was administered to faculty members and research scholars of the JNU and JMI to collect data regarding the use of on-line database. The survey reveals that all of the faculty members and research scholars are aware of the availability of on-line databases and largely use them for reference purposes in their research work and studies. The degree of usefulness and utilization of on-line databases is high among the universities' faculty members and research scholars. The survey further reveals that the respondents from both universities are aware of the search options for accessing on-line databases. It is also found that a large number of respondents of JNU and JMI are using field searching and Boolean operators to access information from on-line databases.  相似文献   
177.
This study discusses the industrial training programme at the University of Malaya in Malaysia, specifically the issues that need to be addressed in order to enhance the employability skills of graduates. Findings from the feedback obtained from trainees and organizations in the 2008/2009 academic session were examined in terms of the extent to which trainees felt they were prepared for their training, and the extent to which the tasks given to them during their training were appropriate. Further, trainees’ self-rating of particular skills and industry’s rating of the trainees were also examined. The feedback is discussed in the context of the need to equip graduates with employability skills, an issue facing Higher Education Providers worldwide. The findings indicate that most of the students were prepared to face the world of work. However, there were several issues which needed attention. These included the need to address the possible mismatch between the tasks assigned to trainees and their areas of study, and the need to enhance English language competency and particular soft skills throughout their degree programme. Continuous input from industry is also necessary to ensure that the training benefits all parties and contributes to the employability skills of trainees.  相似文献   
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The okra germplasm was screened for salinity tolerance at the seedling stage and during plant ontogeny. Substantial variation existed in okra for salinity tolerance at the seedling stage. An 80 mmol/L NaCl concentration was suitable for discriminating tolerant and non-tolerant okra genotypes. The pooled ranking of the genotypes, based on individual rankings for each trait (root and shoot length, germination percentage, and relative Na+ and K+) in individual NaCl concentrations, was effective for selecting tolerant genotypes. Genotypes selected at the seedling stage maintained their tolerance to NaCl during plant ontogeny, suggesting that screening of the germplasm entries and advanced breeding materials for salt tolerance at the seedling stage is effective. Among 39 okra genotypes, five were identified as the most tolerant genotypes and showed potential for use in breeding programs that focus on the development of salt-tolerant, high-yield okra cultivars.  相似文献   
179.
美国国内对伊斯兰教的讨论遮盖了美国穆斯林群体的多样性。最近开展的一项围绕美国当地女性查经班或古兰经研究小组的调查,对美国国内固有的性别认同的僵化观点提出了质疑。查经班集会是进行讨论、组织和社交的空间,对美国国内相关话语的讨论揭示了其成员对自身宗教和种族身份的认同。在当地社区,这些女性穆斯林移民群体正在积极塑造她们独特的美国南亚裔女性穆斯林的身份特征。  相似文献   
180.
All stakeholders are aware of the importance of measuring performance in higher education at the university/college level. Generally the performance indicators used for this purpose have focused on graduation rates and/or final examination scores, rather than the performance-enabling processes. Further, the most commonly used method for knowledge transfer is the traditional classroom teaching, which should be tracked/monitored continuously during its delivery process. It can help in the detection and correction of existing and impending problems, if any, in the teaching and learning processes. Further, the students’ attitude towards learning, that is, their readiness/willingness and interest should also be taken into consideration while measuring the performance of classroom teaching.

In the present paper, the model for measuring classroom performance illustrated by Grygoryev and Karapertrovic (2005) Grygoryev, K. and Karapetrovic, S. 2005. Tracking classroom teaching and learning: an SPC application. Quality engineering, 17: 405418. [Taylor & Francis Online] [Google Scholar] is used to measure the performance of under-graduate Engineering students in two BTech. (Mechanical) courses, namely, fluid mechaincs (FM) and experimental methods and analysis (EMA). Classroom assessment techniques (CATs) along with the statistical process control (SPC) have been used to analyse the learning performance. Further, the data for student's readiness and interest factors are collected and their positive influences on knowledge gain are established.  相似文献   

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