2008 Benjamin Franklin medal in life science is Presented to Victor Ambros, Ph.D. (University of Massachusetts Medical School, Worcester, Massachusetts), Gary Ruvkun, Ph.D. (Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts) and David Baulcombe, Ph.D., FRS (University of Cambridge, Cambridge, UK)

The discovery of small RNAs that can turn off genes has given us a new way to think about how genes are regulated. These molecules are present in all complex organisms and are thought to regulate upwards of 30% of human genes. Due to their small size, their discovery was surprisingly recent and was underappreciated initially. Beginning with two back-to-back papers published in 1993, the labs of Victor Ambros and Gary Ruvkun reported the first small RNA (now known as a microRNA or miRNA) and how it regulated a target mRNA in the roundworm Caenorhabditis elegans through base-pairing interactions. It took until 1999 for another report to document novel small RNAs in complex systems, when David Balcoumbe discovered similarly sized molecules, now known as small interfering RNAs or siRNAs, that were associated with shutting off or “silencing” genes in plants. A frenzy of reports on small RNAs and their roles in turning off genes ensued with many researchers including Ambros, Ruvkun, and Baulcombe prominently participating. Almost instantly it became clear that small RNAs were not a quaint oddity exclusive to the worm, and molecular biology was never the same. Now we know that these molecules are critical for normal growth and development, are associated with cancer and other diseases, and have tremendous applied potential to improve agriculture and human health.     

The Aftermath of Hobby Lobby and Obergefell: A Reconceptualization of Religious Freedom in the United States and its Potential Implications for Public Schools and Pluralist Democracies

Restricting public employees' free exercise rights or the State to maintain neutrality toward religion has been longstanding precedent in the United States. It has certainly been the case in US public schools beginning in the 1940s and affirmed through the courts over and again through much of the 20th century. The aftermath of 2 recent Supreme Court decisions challenges this long-held precedent, however, as it has led to several instances in which public employees have requested religious exemptions from their professional obligations (e.g., Kentucky court clerk Kim Davis' refusal to grant marriage certificates to same-sex couples). This article provides a foundational framework for exploring the recent reconceptualization of religious freedom and its possible implications for public schools and the larger project of advancing a liberal, pluralist democracy were teachers to refuse to fulfill central elements of their job on the basis of religious objections.     

On the Meanings of Self‐Regulation: Digital Humanities in Service of Conceptual Clarity

Self‐regulation is of interest both to psychologists and to teachers. But what the word means is unclear. To define it precisely, two studies examined the American Psychological Association's system of controlled vocabulary—specifically, the 447 associated terms it presents—and used techniques from the Digital Humanities to identify 88 closely related concepts and six broad conceptual clusters. The resulting analyses show how similar ideas are interrelated: self‐control, self‐management, self‐observation, learning, social behavior, and the personality constructs related to self‐monitoring. A full‐color network map locates these concepts and clusters relative to each other. It also highlights some of the interests of different audiences, which can be described heuristically using two axes that have been labeled abstract versus practical and self‐oriented versus other‐oriented.     

Criminology/Criminal Justice Representation in the Discipline of Sociology: Changes between 1992 and 2002

This paper examines changes in the representation of criminology, as an area of specialization, in the discipline of sociology between 1992 and 2002. Utilizing the ASA Guide to Graduate Programs in Sociology, we note faculty areas of specialization. We expect that criminology will appear more often as a specialty area in 1992 than 2002. All full‐time faculty in U.S. graduate programs in sociology are included in the analyses. We found no significant change in listing criminal justice as a specialty between 1992 and 2002. Our findings suggest that faculty with terminal degrees from less prestigious institutions and those who teach in less prestigious institutions are more likely to list criminology as a specialty area.     

Beginning teachers' conceptual understandings of effective history teaching: examining the change from “subject knowers” to “subject teachers”

This article reports the investigation of change in preservice teachers' conceptions of effective history teaching across a secondary history methods course in a postgraduate diploma of education program. Using concept mapping to plot shifts in their expressed reflections, data were obtained that indicate personal constructs of effective history teaching based around participants' map structures, curriculum understandings, knowledge of subject matter, knowledge of learners, knowledge of pedagogies, and pedagogical content knowledge. The purpose of this article is twofold: to present the findings of research exploring the growth in conceptual understandings of early career history teachers promoted through the use of concept maps, and to discuss the participants' response to tangible opportunities to reflect on their own conceptual understandings of history teaching.     

Assessing the Organizational Social Context (OSC) of child welfare systems: Implications for research and practice

ObjectiveThe study: (1) provides the first assessment of the a priori measurement model and psychometric properties of the Organizational Social Context (OSC) measurement system in a US nationwide probability sample of child welfare systems; (2) illustrates the use of the OSC in constructing norm-based organizational culture and climate profiles for child welfare systems; and (3) estimates the association of child welfare system-level organizational culture and climate profiles with individual caseworker-level job satisfaction and organizational commitment.MethodsThe study applies confirmatory factor analysis (CFA) and hierarchical linear models (HLM) analysis to a US nationwide sample of 1,740 caseworkers from 81 child welfare systems participating in the second National Survey of Child and Adolescent Wellbeing (NSCAW II). The participating child welfare systems were selected using a national probability procedure reflecting the number of children served by child welfare systems nationwide.ResultsThe a priori OSC measurement model is confirmed in this nationwide sample of child welfare systems. In addition, caseworker responses to the OSC scales generate acceptable to high scale reliabilities, moderate to high within-system agreement, and significant between-system differences. Caseworkers in the child welfare systems with the best organizational culture and climate profiles report higher levels of job satisfaction and organizational commitment. Organizational climates characterized by high engagement and functionality, and organizational cultures characterized by low rigidity are associated with the most positive work attitudes.ConclusionsThe OSC is the first valid and reliable measure of organizational culture and climate with US national norms for child welfare systems. The OSC provides a useful measure of Organizational Social Context for child welfare service improvement and implementation research efforts which include a focus on child welfare system culture and climate.