RGFP966 inactivation of the YAP pathway attenuates cardiac dysfunction induced by prolonged hypothermic preservation

Journal of Zhejiang University-SCIENCE B - Oxidative stress and apoptosis are the key factors that limit the hypothermic preservation time of donor hearts to within 4–6 h. The aim of this...     

Recognition of substantial equivalence of engineering competence: the Canada—France mutual recognition agreement

Recognition at the full professional level of engineers coming from two different countries with totally different systems is a very difficult task. However, in the context of globalization of all human activities, particularly engineering services, it is essential that well-developed countries take very serious efforts using an open-minded approach to establish the parameters that will permit the ultimate objective of international recognition to be achieved. While there are many ways to move toward this objective, one recognized method of making very important steps is certainly the signature of mutual recognition agreements by major players in the trade of engineering services. In this context, this paper presents the features of a bilateral agreement that has been signed between France and Canada for the recognition of engineers at the full professional level from both countries. This agreement is the first of its kind for Canada. Many features of the agreement are worthy of note for others trying to identify the parameters to achieve an agreement between two countries having very different systems. How this success was achieved is explained, giving full attention to those factors that contributed to the conclusion of this agreement.     

Choice of Academic Major at a Public Research University: The Role of Gender and Self-Efficacy

Females are underrepresented in certain disciplines, which translates into their having less promising career outlooks and lower earnings. This study examines the effects of socio-economic status, academic performance, high school curriculum and involvement in extra-curricular activities, as well as self-efficacy for academic achievement on choices of academic disciplines by males and females. Disciplines are classified based on Holland’s theory of personality-based career development. Different models for categorical outcome variables are compared including: multinomial logit, nested logit, and mixed logit. Based on the findings presented here, first generation status leads to a greater likelihood of choosing engineering careers for males but not for females. Financial difficulties have a greater effect on selecting scientific fields than engineering fields by females. The opposite is true for males. Passing grades in calculus, quantitative test scores, and years of mathematics in high school as well as self-ratings of abilities to analyze quantitative problems and to use computing are positively associated with choice of engineering fields.     

Experimental and numerical investigation of buckling in rectangular steel plates with groove-shaped cutouts

Steel plates are widely used in various structures, such as the deck and bodies of ships and bridges, and in the aerospace industry. In many instances, these plates are subjected to axial compression loads that predispose the sheets to instability and buckling. In this study, we investigate the buckling and post-buckling behaviors of steel plates having groove-shaped cutouts of various dimensions and angles using finite element method (FEM) (by ABAQUS software) and experimental tests (by an Instron servohydraulic machine). Boundary conditions were clamped by supports at upper and lower ends and free supports at the other edges. The results of both numerical and experimental analyses are compared, which show a very good agreement between them. Finally, based on the experimental findings, formulas are presented for the determination of the buckling load of such plates.     

Meaning in life and school guidance programs: Adolescents’ voices from Hong Kong

International Journal for Educational and Vocational Guidance - This study provides insights into how Chinese adolescents in Hong Kong interpret the concept of “meaning in life.” Data...     

Terminal iterative learning control for discrete-time nonlinear systems based on neural networks

The terminal iterative learning control is designed for nonlinear systems based on neural networks. A terminal output tracking error model is obtained by using a system input and output algebraic function as well as the differential mean value theorem. The radial basis function neural network is utilized to construct the input for the system. The weights are updated by optimizing an objective function and an auxiliary error is introduced to compensate the approximation error from the neural network. Both time-invariant input case and time-varying input case are discussed in the note. Strict convergence analysis of proposed algorithm is proved by the Lyapunov like method. Simulations based on train station control problem and batch reactor are provided to demonstrate the effectiveness of the proposed algorithms.