L∞-gain analysis for positive singular time-delay systems

This paper is devoted to the characterization of L_∞-gain for positive singular systems with time-varying delays. First, we introduce an augmented system to replace the original system in order to analyze the positivity of singular systems with time-varying delays. By investigating the monotonicity of state trajectory, the L_∞-gain for singular system with constant delays is characterized. Then, by comparing the trajectories of time-varying delay system and constant delay case, we finally propose the L_∞-gain for singular system with time-varying delays. It is shown that the L_∞-gain of positive singular systems is independent of the magnitude of delays.     

Cyclic olefin copolymer based microfluidic devices for biochip applications: Ultraviolet surface grafting using 2-methacryloyloxyethyl phosphorylcholine

This report studies the surface modification of cyclic olefin copolymer (COC) by 2-methacryloyloxyethyl phosphorylcholine (MPC) monomer using photografting technique for the purpose of biointerface applications, which demonstrate resistance to both protein adsorption and cell adhesion in COC-based microfluidic devices. This is essential because the hydrophobic nature of COC can lead to adsorption of specific compounds from biological fluids in the microchannel, which can affect the results during fluidic analysis and cause clogging inside the microchannel. A correlation was found between the irradiation time and hydrophobicity of the modified substrate. Static water contact angle results show that the hydrophilicity property of the MPC-grafted substrate improves with increasing irradiation time. The contact angle of the modified surface decreased to 20 ± 5° from 88 ± 3° for the untreated substrate. The surface characterization of the modified surface was evaluated using x-ray photoelectron spectroscopy (XPS) and Fourier transform infrared spectroscopy (FTIR spectroscopy). Attenuated total reflection-FTIR and XPS results show the presence of the phosphate group (P-O) on modified COC substrates, indicating that the hydrophilic MPC monomer has successfully grafted on COC. Finally, it was demonstrated that cell adhesion and protein adsorption on the MPC modified COC specimen has reduced significantly.     

走向现实的“纳米催化”

作为关键和核心技术,催化在能源、环境、农业以及人类健康等领域正发挥着越来越重要的作用。借助纳米科学和技术的发展和进步,以纳米体系的电子调制为理论基础,通过纳米层次对催化剂形貌的调变,高活性晶面定量设计和控制暴露得以实现;从理论上预示并实验验证了碳纳米管的“协同限域效应”和金属??氧化物的“界面限域效应”。根据大量的实验研究和理论分析,提出“纳米限域催化”的新概念,并在CO氧化、合成气定向转化和燃料电池相关的催化过程中得到了初步验证。     

合作方技术获取对企业绩效的作用机制研究

合作方技术获取对于企业绩效提高有重要的促进作用,而获取技术作为外部资源首先要通过吸收和利用过程转化为企业自身的能力才能促进企业的绩效提升。同时,在目前的转型经济背景下,商业和制度环境的不完善也提高了管理者社会资本在企业合作和资源获取过程中的重要性。但是,很少有从整合的视角对企业合作方技术获取、内部研发能力、管理者社会资本和企业绩效间的关系和作用路径的研究。论文建立实证模型整合并分析合作方技术获取对于企业绩效的作用路径和管理者社会资本对于合作方技术获取作用路径的影响机制。结果表明,合作方技术获取对于企业绩效的促进作用是通过企业内部研发能力的改进作为部分中介实现的;企业高层管理者商业联系有效提高了合作方技术获取对于内部研发能力的正向效果;而政治联系却降低了这一过程的效果。     

Bandpass sorting of heterogeneous cells using a single surface acoustic wave transducer pair

Separation and sorting of biological entities (viruses, bacteria, and cells) is a critical step in any microfluidic lab-on-a-chip device. Acoustofluidics platforms have demonstrated their ability to use physical characteristics of cells to perform label-free separation. Bandpass-type sorting methods of medium-sized entities from a mixture have been presented using acoustic techniques; however, they require multiple transducers, lack support for various target populations, can be sensitive to flow variations, or have not been verified for continuous flow sorting of biological cells. To our knowledge, this paper presents the first acoustic bandpass method that overcomes all these limitations and presents an inherently reconfigurable technique with a single transducer pair for stable continuous flow sorting of blood cells. The sorting method is first demonstrated for polystyrene particles of sizes 6, 10, and 14.5 μm in diameter with measured purity and efficiency coefficients above 75 ± 6% and 85 ± 9%, respectively. The sorting strategy was further validated in the separation of red blood cells from white blood cells and 1 μm polystyrene particles with 78 ± 8% efficiency and 74 ± 6% purity, respectively, at a flow rate of at least 1 μl/min, enabling to process finger prick blood samples within minutes.     

新型研发机构促进理工类高校科技成果转化的路径分析

针对理工类高校科技成果转化的现状,从新型研发机构的视域出发,从高校响应科技成果转化政策的解释框架、产学研深度融合的技术创新体系、高校科技成果产业化价值链等方面的探究,对新型研发机构促进科技成果转化的特色发展模式进行分析,提出有助于推动理工类高校科技成果转化的对策建议.     

基于CIM的相似度综合评价算法

相似度计算是自动问答领域里的重要内容。为了保证候选答案集中各答案能具备合理的排序,解决传统自动问答系统不能高效的综合评价相似度问题,提出利用综合指数法对关键词相似度、语义相似度等进行综合评价,得到综合相似度。并针对部分候选答案冗余信息过多,不利于答案提取的情况,设计了衰减相似度参数,用来解决句子冗余信息对答案提取的影响。实验结果表明,综合指数法的相似度算法能够有效的提高问答的正确率。     

Robust self-triggered MPC with fast convergence for constrained linear systems

In this paper, a robust self-triggered model predictive control (MPC) scheme is proposed for linear discrete-time systems subject to additive disturbances, state and control constraints. To reduce the amount of computation on controller sides, MPC optimization problems are only solved at certain sampling instants which are determined by a novel self-triggering mechanism. The main idea of the self-triggering mechanism is to choose inter-sampling times by guaranteeing a fast decrease in optimal costs. It implies a fast convergence of system states to a compact set where it is ultimately bounded and a reduction of computation times to stabilize the system. Once the state enters a terminal region, the system can be stabilized to a robust invariant set by a state feedback controller. Robust constraint satisfaction is ensured by utilizing the worst-case set-valued predictions of future states in such a way that recursive feasibility is guaranteed for all possible realisations of disturbances. In the case where a priority is given to reducing communication costs rather than improvement in control performance in a neighborhood of the origin, a feedback control law based on nominal state predictions is designed in the terminal region to avoid frequent feedback. Performances of the closed-loop system are demonstrated by a simulation example.     

Convenient surface functionalization of whole-Teflon chips with polydopamine coating

This paper presents a convenient strategy to modify the surface of whole-Teflon microfluidic chips by coating the channel walls with a thin layer of polydopamine (PDA) film, which is formed by oxidation-induced self-polymerization of dopamine in alkaline solution. Two coating strategies, static incubation and dynamic flow, are demonstrated and used for tuning the physical and chemical properties of the coated channel walls. The functionalized surfaces were investigated with the contact angle, X-ray photoelectron spectroscopy, and atomic force microscopy measurements. The coating time was optimized according to the fluorescent intensity of the green fluorescent protein immobilized on the modified surface. Applications of the PDA-modified Teflon microchips in bioanalysis were demonstrated with a typical sandwich immunoassay. Moreover, long-term cell culture experiments on modified and native Teflon chips revealed that the chip biocompatibility can be greatly improved with PDA coating. The results indicate that the surface properties of the Teflon can be easily controlled by the PDA modification, thus greatly expanding the application scope of whole-Teflon chips for various chemical and biological research fields.     

稀土产业链全球格局现状、趋势预判及应对战略研究

稀土是支撑高端技术创新和新兴产业发展的关键原材料,也是国际争夺的重要战略性矿产资源。2011年以来,美西方加大稀土供应链及产业链“去中国化”的步伐,世界稀土多元供应格局正在加速形成。文章立足于全球稀土的全产业链视角,系统开展对稀土全产业链的国际格局现状分析与演变研判,剖析识别稀土在大国博弈中的战略价值,为构建我国稀土全球化发展战略提供措施建议。