Cr3锻钢平整工作辊"桔皮"原因分析及改进措施

某热轧带钢厂Cr3材质锻钢平整工作辊每次上机服役仅生产1000t钢卷即需换辊修磨，严重影响产品质量和轧辊使用寿命。对Cr3材质锻钢工作辊进行硬度、金相组织等检验发现，虽然辊面金相组织正常，但是硬度偏低，导致在使用过程中出现塑性变形，表明这种材质的工作辊不适合在“干”平整的工况条件下用作热轧平整工作辊。建议采用具有更高耐磨性、更高热稳定性的高速工具钢、半高速工具钢和改进型高NiCr无限冷硬铸铁工作辊等材质工作辊代替Cr3材质锻钢工作辊，以提高生产效率和轧辊寿命。     

Contradictions,dialectical oppositions and shifts in teaching mathematics

The study reported in this paper concerns the tensions and conflicts that teachers experience while they enact a new set of reform-oriented curricular materials into their classrooms. Our focus is οn the interactions developed in two groups of teachers in two schools for a period of a school year. We use Activity Theory to study emerging contradictions and we elaborate on the construct of dialectical opposition to understand the nature of these contradictions and their potential for teacher learning. We provide evidence that discussions about contradictions and their dialectical character in the two groups support teachers to engage differently in mathematics teaching and learning and carry potentials for shifts in the practices that evolve in their classrooms. Our study addresses empirically in the context of mathematics teaching the philosophical claim about the role of contradictions as a driving force for any dynamic system.     

Returns on vocational education over the life cycle: Between immediate labour market preparation and lifelong employability

An important issue in the design of secondary-level education is the balance between conveying general and occupation-specific (vocational) skills. On the one hand, vocationally oriented programmes, providing occupation-specific skills with immediate labour market relevance, have repeatedly been shown to secure safe pathways into employment. On the other hand, these programmes tend to put less emphasis on developing general knowledge, skills and competencies, including numeracy and literacy, which are foundational to lifelong learning. Hence, when the needs of the labour market change, employees who opted for a vocational track when they were at secondary school risk being less flexible in adapting to such changes later in their career. The authors of this article examine whether this results in a trade-off between short-term gains and long-term losses by considering differences in the labour market careers of vocationally and generally educated respondents in the 2012 Programme for the International Assessment of Adult Competencies (PIAAC). Their results suggest that early labour market benefits of vocational specialisation decrease over time; the authors relate this to its lower ability to equip secondary school students – future employees – with skills for lifelong learning.     

Random vibration analysis of switching apparatus based on Monte Carlo method

The performance in vibration environment of switching apparatus containing mechanical contact is an important element when judging the apparatus’s reliability. A piecewise linear two-degrees-of-freedom mathematical model considering contact loss was built in this work, and the vibration performance of the model under random external Gaussian white noise excitation was investigated by using Monte Carlo simulation in Matlab/Simulink. Simulation showed that the spectral content and statistical characters of the contact force coincided strongly with reality. The random vibration character of the contact system was solved using time (numerical) domain simulation in this paper. Conclusions reached here are of great importance for reliability design of switching apparatus.     

Homoharringtonine induces apoptosis of endothelium and down-regulates VEGF expression of K562 cells

Homoharringtonine (HHT) has currently been used successfully in the treatment of acute and chronic myeloid leukemias and has been shown to induce apoptosis of different types of leukemic cells in vitro. Emerging evidence suggests that angiogenesis may play an important role in hematological malignancies, such as leukemia. How ever, whether HHT can relieve leukemia by anti-angiogenesis is still unknown. We investigated the anti-angiogenesis potential of HHT with the human umbilical vein endothelial cell line (ECV304) and leukemic cell line (K562) in vitro. Cellular proliferation was determined by MTT assay and apoptosis was analyzed by flow cytometry. The mRNA expression of vascular endothelial growth factor (VEGF) was assessed by RT-PCR and VEGF protein production was detected by Western blot. Inhibition of cell proliferation and induction of apoptosis by HHT were discovered in ECV304 cells, and appeared in a dose- and time-dependent manner. Also, treatment with HHT caused down-regulation of VEGF mRNA expression in K562 cells in similar dose- and time-dependent manner and inhibition of VEGF protein production in K562 cells in response to the enhancing concentration of HHT. The results demonstrated that HHT could also induce apoptosis in endothelium and down-regulate VEGF expression in K562 cells. In conclusion, we believe HHT has anti-angiogenesis potential and speculate that HHT might exert its anti-leukemia effects via reduction of angiogenesis.     

教你正确用(二十三)

Dos and Don'ts in America--美国文化点滴 Living in a different culture sometimes can be stressful. The term "Culture Shock" is often used to describe a person's excitement,confusion, frustration, and eventual adaptation when getting into a new culture from his home culture.     

The elusive nature of whole system improvement in education

Whole system improvement—where the vast majority of schools improve—is difficult to achieve. Some jurisdictions use what turns out to be ‘wrong’ policy drivers like testing and evaluation. Rather, success turns out to depend on changing the culture of schools and their relationship to the infrastructure of policies and regulation. I examined the six cases studies in the light of whole system change criteria. Two of the case studies, South Africa and India, represent limited but useful examples in that they focus on basic skills like literacy. A second set of two studies, Escuela Nueva and LCP in Mexico, represent strong examples of how bottom up strategies can spread to significant levels. The final two, Long Beach in the US and Ontario, are strong examples of how deep change can be accomplished by focusing on a few core priorities and then building a culture over a number of years to support and sustain the changes. The paper then draws conclusions about the conditions that will be required for large scale change to occur.     

一种用于宽动态范围上的高精度散射测量的标准方法

The co-effect of transmitted power fluctuation and system nonlinearity produce deviations in scatterometer measurement results . An internal calibration method to deal with this problem is proposed. The method can result in more precise scatterometric measurements in a wide range. The basic principle of the method is combining real-transmitted-power detection with the calibration of system nonlinearity. A practical scheme to implement the method is also presented, which is developed based on a special designed mechanism of a microwave radiometer-scatterometer combined system.