An algorithm for Eigenvalue assignment in multi-input systems

This paper describes a computational method for solving the problem of eigenvalue assignment in a multi-input linear system. The given system is first reduced to an upper block Hessenberg form by means of orthogonal state coordinate transformations. It is then shown how a sequence of state feedback matrices and orthogonal state coordinate transformations can be applied to obtain a block triangular structure for the resulting state matrix, where the matrices on the diagonal are square matrices in upper Hessenberg form and of dimensions equal to the controllability indices of the multi-input system. Furthermore, the structure of the corresponding input matrix is such that the problem of eigenvalue assignment in the multi-input system can be reduced to several single-input eigenvalue assignment problems where the dimensions of the single-input systems are equal to the controllability indices of the multi-input system.     

Comprehending instructions for using pharmaceutical products in rural Kenya

This paper reports two studies on comprehension of pharmaceutical texta containing pictorial and written instructions by mothers in rural Kenya. The subjects were asked to read and recall instructions for preparing and administering a solution for the treatment of dehydration due to diarrheal disease in children. A set of pictures describing the preparation procedure, together with written text instructions under two conditions, (a) original, as in the commercial product, and (b) revised, to include familiar terminology and explanations of some procedures, were presented to two groups of Kenyan mothers. The verbal protocols generated were transcribed and analyzed using propositional representation of instructional procedures.The results showed that mothers recalled the procedures for the preparation as in the pictures but not those presented in the written instructions. The written instructions were generally found to be difficult, with the original text being more difficult than the revised text. Any conflicting information between the written and pictorial instructions was resolved by selecting the familiar procedure. The information recalled from the revised text that was recalled was that which supported the procedures in the pictures. The results have implications for writing adequate pharmaceutical texts for users such that little room is left for misinterpretation.     

Cardiorespiratory Response to Exercise on a Large Therapeutic Roll

Purpose

Large therapeutic rolls (LTR) and balls are popular rehabilitation tools and have also been advertised as cardiovascular training devices. The aim of this study was to determine if individuals of varying fitness levels would reach aerobic training levels by evidence-based standards as described in American College of Sports Medicine (ACSM) publications.

Methods

Fourteen volunteers performed a maximal exercise test and on subsequent days, two submaximal exercise tests on the LTR (LTR-A and -B). LTR-A consisted of four 5-minute stages of exercise at progressive intensity levels. LTR-B included 20 minutes of continuous exercise. Oxygen consumption (VO₂) and heart rate (HR) during exercise on the LTR were compared with ACSM recommended standards.

Results

The average (range) peak intensity achieved during LTR-A was 66.8% (51.7-82.7%) of maximal VO₂ reserve (VO₂R) and 82.9% (70.7%-91.2%) of maximal heart rate (HR_max). During LTR-B, HR and VO₂ of all participants was maintained at moderate exercise intensity and averaged 56% of VO₂R and 78% of HR_max during the 20 minute exercise period.

Conclusions

These findings suggest that individuals with a wide range of aerobic fitness are able to reach and maintain aerobic training levels with appropriate exercise on a large therapeutic roll or ball.Key Words: large therapeutic roll, Swiss Ball, aerobic exercise, exercise intensity     

ANCHORING ADHD SYMPTOMS TO MENTAL AGE

The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM‐5), requires that symptoms of ADHD must be developmentally inappropriate in order for an ADHD diagnosis to be considered. Because the DSM‐5 does not specifically outline procedure for determining developmental inappropriateness of behaviors, practitioners do not have guidance for making this consideration. To explore the relationship between mental age and behavior ratings of ADHD symptoms, the cognitive and behavioral data from 50 children who were evaluated in a school or clinic were compiled for this study. Cognitive ability scores were used to calculate mental age and behavior rating scores were then recalculated using the assessed mental age. Using the recalculated behavior ratings, scores based on mental age decreased significantly on the Attention Problems, Hyperactivity, and Atypicality scales of the BASC‐2. Additionally, as the discrepancy between mental and chronological age increased, larger differences in scores were found.     

Conversations among Coal Miners in a Campaign to Promote Hearing Protection

Although working in a coal mine can diminish one's hearing capabilities by 50%, not until 2000 did federal laws require companies to establish noise standards in order to help prevent hearing loss among their employees. Since then, researchers have worked with safety administrators to develop effective messages promoting hearing protection and testing. This research assessed the effects of campaign messages on discussing campaign postcards and talking with others about a helmet-sticker incentive. The results, which are discussed with a focus on future campaigns, indicate that hearing-related attitudes, intentions, and behaviors are the most influenced by messages that were affectively neutral and least influenced by messages that were affectively negative.     

Bardet–Biedl Syndrome: A Rare Cause of Chronic Kidney Disease

Bardet-Biedl syndrome (BBS) is a rare autosomal recessive condition characterized by retinitis pigmentosa, postaxial polydactyly, central obesity, and renal involvement. Renal failure is the commonest cause of death. We report a case of BBS with chronic kidney disease (CKD) at younger age (17 year) from India. This diagnosis should be considered in patients with renal disease and the characteristic phenotype of retinitis pigmentosa, postaxial polydactyly and central obesity. These patients should undergo regular monitoring of renal function test to early diagnosis and treatment of CKD to prevent morbidity and mortality. Renal transplantation is a viable option of renal replacement therapy in these patients. These findings are valuable for comparing phenotype of BBS patients with CKD from various national and international centers.     

Down Syndrome with End-Stage Renal Disease

Down syndrome is one of the most common genetic causes of learning disabilities in children. Although the incidence of renal and urological involvement in Down syndrome is not very common, monitoring of patients with Down syndrome for renal diseases should be done regularly as patient’s age into the second and third decades. With increased survival, it appears that a growing number of these patients present with chronic renal failure. Down syndrome patients are apparently not suited for peritoneal dialysis because of lacking cooperation. This procedure can be prone to failure, mainly because of an increased risk of peritonitis. Handling such patients especially those on peritoneal dialysis is challenging. Here we report a case of Down syndrome with end-stage renal disease treated with hemodialysis for 6 months. To the best of our knowledge and current literature review this is the first case report of a patient with Down syndrome undergoing hemodialysis.     

Biceps femoris long head muscle fascicle length does not differ between sexes

ABSTRACT

Hamstring strain injury (HSI) rates are higher for males vs. females. This cross-sectional study investigated if inherent differences in biceps femoris long head (BF_LH) fascicle length (Lf) exist between recreationally active males and females (i.e., individuals without specific training practice history). Twenty-four young healthy participants (12 males; 12 females) had their BF_LH muscle architecture (Lf, pennation angle [θp], and muscle thickness [MT]) measured using B-mode ultrasonography. Eccentric and isometric knee flexion strength were also assessed. BF_LH Lf did not differ between sexes when expressed in absolute terms (males, 81.5 ± 14.7 mm; females, 73.6 ± 15.9 mm, P = 0.220, effect size (ES) = 0.52) or relative to femur length (0.140 ≤ P ≤ 0.220, ES = 0.63). Similarly, BF_LH θp did not differ between sexes (P = 0.650) but BF_LH MT was 18.9% larger for males vs. females (P = 0.024, ES = 0.99). Isometric and eccentric knee flexion strength was greater for males vs. females in absolute terms ([both] P < 0.001, 2.00 ≤ ES ≤ 2.27) and relative to body mass ([both] P < 0.001, 1.93 ≤ ES ≤ 2.13). In conclusion, factors other than BF_LH Lf seem likely to be implicated in higher male vs. female HSI rates.