Fostering conceptual change and critical reasoning about HIV and AIDS

One of the challenges of science education is for students to develop scientific knowledge that is personally meaningful and applicable to real‐life issues. This article describes a middle‐school science intervention fostering adolescents' critical reasoning in the context of HIV by strengthening their conceptual understanding of HIV biology. The intervention included two components: critical reasoning activities that fostered knowledge integration and application to real‐world problem solving, and science writing activities that promoted argument building. Two seventh‐grade classes participated in the study. One class participated in the critical reasoning and writing activities (CR&W); the other class participated in critical reasoning activities only (CR group). Results demonstrate significant pre‐ and posttest improvements on measures of students' HIV knowledge, HIV understanding, and critical reasoning about realistic scenarios in the context of HIV, with the improvements being greater in the CR&W group. The discussion focuses on the role of conceptual knowledge in health reasoning, the role of science writing in fostering knowledge integration, and the benefits of a “thinking curriculum” approach to integrated health and science education. © 2007 Wiley Periodicals, Inc. J Res Sci Teach 44: 844–863, 2007     

Thyroidal regulation of substrate kinetics properties of cytochrome oxidase in rat liver mitochondria

Effects of thyroidectomy (T_x) and subsequent treatment with 3,5,3’-triiodothyronine (T₃), and combined treatment (T_R) with T₃ + thyroxine (T₄) on substrate kinetics properties of cytochrome oxidase of rat liver mitochondria were examined. T_x resulted in lowering of cytochromes content with decrease in the enzyme activity, and K_m and V_max. T₃ and T_R regimens restored the cytochromes contents and the V_max values to normal. In control, T₃ and T_R groups the enzyme activity resolved in two kinetic components; in T_x group three kinetic components were evident. The K_m values for all components decreased significantly in the experimental groups with concomitant increase in catalytic efficiency, K_cat/K_m. Significant alterations in the contents of total phospholipid and of cholesterol were noted while the changes in the phospholipids composition were only of restricted nature. Regression analysis revealed that total phospholipid, cholesterol and phosphatidylcholine, phosphatidylethanolamine play significant role in fine tuning the enzyme activity.     

《四库全书总目》善本观初探

首次从正反两方面探讨《四库全书总目》的善本观,认为《总目》之善本观是考订家之善本现,而非赏鉴家之善本观.     

An Investigation of Counselor Educators' Attitudes Toward Evidence‐Based Practices

Evidence‐based practices (EBPs) receive little attention in counselor education curricula despite the ethical obligation for counselor educators to teach EBPs to counseling students. This study investigates counselor educators’ attitudes toward EBPs along with perceived barriers to the inclusion of EBPs in counselor education curricula.     

A Quantitative Survey of Knowledge of Reproductive Health Issues of 12-14-year-old Girls of Different Ethnic and Religious Backgrounds in Iran: Implications for education

A quantitative research study was conducted to examine the knowledge of girls aged 12-14 years regarding reproductive health in five cities in Iran with different ethnic and cultural majorities. A cross-sectional study using a self-administrated questionnaire was conducted among guide school (middle school) pupils. Data analysis was based on 1,893 questionnaires. The internal consistency of the items was 0.80. Overall, knowledge level was unsatisfactory. An association between age and knowledge about reproductive health was found. Additionally, there was a statistically significant difference in the knowledge of reproductive health between cities. The findings suggest that reproductive health education initiatives that involve mothers may be most appro priate in terms of cultural and religious sensitivities, and be in keeping with the wishes of the girls themselves.     

Notable and Emerging Variants of SARS-CoV-2 Virus: A Quick Glance

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the etiological agent of coronavirus disease-2019 (COVID-19), is a highly contagious pathogenic coronavirus to emerge and spread in human populations. Although substantial exertions have been laid to avert spread of COVID-19 by therapeutic and preventive countermeasures, but emergence of SARS-CoV-2 variants as a result of mutations make the infection more ominous. New viral confers a higher nasopharyngeal viral load, increased viral transmissibility, higher infectiousness, immune escape, increased resistance to monoclonal/polyclonal antibodies from convalescence sera/vaccine, and an enhanced virulence. Thus, it is pertinent to monitor evolving mutations and genetic diversity of SARS-CoV-2 as it is decisive for understanding the viral variants. In this review we provide an overview of colloquial nomenclature and the genetic characteristics of different SARS-CoV-2 variants in the context of mutational changes of the circulating strains, transmissibility potential, virulence and infectivity.     

《经义考通说疏证》序跋

自序《经义考》一书,皇皇三百卷,系清初大儒朱彝尊晚年所编纂之经学文献工具书。朱彝尊(1629—1709),字锡鬯,号竹,秀水(今浙江嘉兴)人。康熙己未(1679)荐举博学鸿词,召试授检讨,入直内廷。彝尊文章尔雅,初在布衣之内,已与王士声价相齐。博识多闻,学有根柢,复     

A family of proportionate normalized subband adaptive filter algorithms

In this paper, the concept of proportionate adaptation is extended to the normalized subband adaptive filter (NSAF), and seven proportionate normalized subband adaptive filter algorithms are established. The proposed algorithms are proportionate normalized subband adaptive filter (PNSAF), μ‐law PNSAF (MPNSAF), improved PNSAF (IPNSAF), the improved IPNSAF (IIPNSAF), the set-membership IPNSAF (SM-IPNSAF), the selective partial update IPNSAF (SPU-IPNSAF), and SM-SPU-IPNSAF which are suitable for sparse system identification in network echo cancellation. When the impulse response of the echo path is sparse, the PNSAF has initial faster convergence than NSAF but slows down dramatically after initial convergence. The MPNSAF algorithm has fast convergence speed during the whole adaptation. The IPNSAF algorithm is suitable for both sparse and dispersive impulse responses. The SM-IPNSAF exhibits good performance with significant reduction in the overall computational complexity compared with the ordinary IPNSAF. In SPU-IPNSAF, the filter coefficients are partially updated rather than the entire filter at every adaptation. In SM-SPU-IPNSAF algorithm, the concepts of SM and SPU are combined which leads to a reduction in computational complexity. The simulation results show good performance of the proposed algorithms.     

Sickle Cell Trait Presenting as Chronic Calcific Pancreatitis with Pseudocyst- A Case Report

Sickle cell disease is known to cause acute pancreatitis either due to gall stones obstructing the pancreatic duct or by vaso-occlusive mechanism. However chronic pancreatitis is a very rare complication in sickle cell anemia. We report a case of sickle cell trait presenting with chronic pancreatitis with pseudo cyst. USG abdomen and CT abdomen confirmed the diagnosis of chronic calcific pancreatitis with pseudocyst. Etiological work up for other causes did not reveal anything except sickle cell trait. This case represents a rare association between chronic calcific pancreatitis and sickle cell trait.     

山东省普通高校高水平运动队所处困境与可持续发展研究

以文献资料、问卷调查和实地调查为基础,对山东省普通高校高水平运动队所面临的主要困难进行了分析,在此基础上,提出深化体制改革、规范招生、拓宽经费来源、加强教练员队伍建设、解决运动员实际问题和开拓市场、创立品牌的建议,旨在为山东省普通高校高水平运动队的可持续发展提供一定的理论和方法支持。