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BackgroundIndividuals with diabetes have greater central arterial stiffness, wave reflections, and hemodynamics, all of which promote the accelerated cardiovascular pathology seen in this population. Acute aerobic exercise has been shown to be an effective strategy for reducing central arterial stiffness, wave reflections, and hemodynamics in healthy individuals; however, the effects of acute aerobic exercise in reducing these outcomes is not well established in people with diabetes. Recently, implementation of high-intensity interval exercise (HIIE) has shown superior improvements in cardiovascular health outcomes when compared to traditional aerobic exercise. Yet, the effect of HIIE on the aforementioned outcomes in people with diabetes is not known. The purpose of this study was to (i) describe the central arterial stiffness, wave reflections, and hemodynamic responses to a bout of HIIE and moderate-intensity continuous exercise (MICE) in adults with diabetes; and (ii) compare the effects of HIIE and MICE on the aforementioned outcomes.MethodsA total of 24 adult men and women (aged 29–59 years old) with type 1 (n = 12) and type 2 (n = 12) diabetes participated in a randomized cross-over study. All participants completed the following protocols: (i) HIIE: cycling for 4 × 4 min at 85%–95% of heart rate peak (HRpeak), interspersed with 3 min of active recovery at 60%–70%HRpeak; (ii) MICE: 33 min of continuous cycling at 60%–70%HRpeak; and (iii) control (CON): lying quietly in a supine position for 30 min.ResultsA significant group × time effect was found for changes in central systolic blood pressure (F = 3.20, p = 0.01) with a transient reduction for the HIIE group but not for the MICE or CON groups. There was a significant group × time effect for changes in augmentation index at a heart rate of 75 beats/min (F = 2.32, p = 0.04) with a decrease following for HIIE and MICE but not for CON. For all other measures of central arterial stiffness and hemodynamics, no significant changes were observed (p > 0.05).ConclusionA bout of HIIE appears to lead to a greater transient reduction in central systolic blood pressure than the reduction observed following MICE; however, both HIIE and MICE improved augmentation index at a heart rate of 75 beats/min in people with diabetes. There was no significant difference in response to HIIE and MICE in all outcomes. This provides preliminary evidence on the role of HIIE on such outcomes in people with diabetes.  相似文献   
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Although the effectiveness of inoculation as a strategy for promoting resistance to attitude change is fairly well established, the potential of inoculation messages to offer cross-protection for related, but untreated, attitudes warrants additional attention from scholars. The reported study tested the “blanket of protection” conferred by inoculation. Participants (N = 118) were randomly assigned to read an inoculation message addressing a target topic and subsequently had their attitudes toward three related, but untreated, topics attacked. The results offer some evidence that inoculation messages can confer cross-protection for related attitudes. Participants in the inoculation condition reported greater perceptions of threat, greater counterarguing, and less attitude change in response to attacks than participants in the control condition for two of the three untreated topics. Counterarguing in response to attacks on untreated attitudes appears to be primarily responsible for cross-protection.  相似文献   
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For this talk, Marks was tasked with summarizing the important trends in scholarly publishing in 45 minutes. The speaker reflected on the rapid changes that have occurred in journal publishing, which followed more than 300 years of relatively slow progress. Marks discussed key technology trends such as data curation, Open Access (OA) mandates, and the changes occurring in the global landscape of scholarly communications and library budgets. Wolters Kluwer Health has been responding to these trends with new publishing experiments including a Platinum OA model in emerging markets. Marks discussed the ways that publishers and libraries need to alter their traditional practices and instill a focus on their customers and communities.  相似文献   
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This article reassesses The People's Choice by Paul Lazarsfeld, Bernard Berelson, and Hazel Gaudet, one of the foundations of communication and voting behavior research. As with most classics, which are often cited but seldom read, we believe this book has much to teach contemporary social scientists. We return to the original context of the research and use voting data from the period with three broad goals: (a) to find ideas and lessons from this work that generally have been overlooked, (b) to suggest new ways of applying these ideas, and (c) to encourage scholars to engage more with this seminal work to understand ideas that are often overlooked when a complex piece of research is reduced to a brief discussion or passing citation.  相似文献   
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