Teaching Bioinformatics and Neuroinformatics by Using Free Web-based Tools

This completely computer-based module''s purpose is to introduce students to bioinformatics resources. We present an easy-to-adopt module that weaves together several important bioinformatic tools so students can grasp how these tools are used in answering research questions. Students integrate information gathered from websites dealing with anatomy (Mouse Brain Library), quantitative trait locus analysis (WebQTL from GeneNetwork), bioinformatics and gene expression analyses (University of California, Santa Cruz Genome Browser, National Center for Biotechnology Information''s Entrez Gene, and the Allen Brain Atlas), and information resources (PubMed). Instructors can use these various websites in concert to teach genetics from the phenotypic level to the molecular level, aspects of neuroanatomy and histology, statistics, quantitative trait locus analysis, and molecular biology (including in situ hybridization and microarray analysis), and to introduce bioinformatic resources. Students use these resources to discover 1) the region(s) of chromosome(s) influencing the phenotypic trait, 2) a list of candidate genes—narrowed by expression data, 3) the in situ pattern of a given gene in the region of interest, 4) the nucleotide sequence of the candidate gene, and 5) articles describing the gene. Teaching materials such as a detailed student/instructor''s manual, PowerPoints, sample exams, and links to free Web resources can be found at http://mdcune.psych.ucla.edu/modules/bioinformatics.     

Abusive parents' reports of child behavior problems: relationship to observed parent-child interactions

PURPOSE: We evaluated the hypothesis that abusive parents' reports may exaggerate rates of child behavior problems in a clinical sample. METHOD: The association between parental ratings of behavior problems and independent observations of child behaviors was examined in a sample of 205 clinic-referred families, 58 of which had a reported history of physical abuse. RESULTS: Relative to the comparison group, parents in the abuse group reported more externalizing problems in their children after controlling for parental psychopathology, and displayed more emotionally controlling and less supportive behavior during parent-child interactions. However, there was no association between abuse history and observed child behaviors during the interaction tasks. Abuse status significantly moderated the association between parent-reported externalizing behaviors and observed demanding behavior by the child; the association was significant among comparison families, but not in the abuse group families. CONCLUSIONS: Results indicate that abusive parents may over-report externalizing behavior problems in their children.     

The response to intervention of English language learners at risk for reading problems

The response to intervention (RTI) of English language learners identified as at risk for reading difficulties in the fall of first grade was examined at the end of first grade and at the end of second grade. Students at risk for reading problems were randomly assigned to intervention or control groups. Intervention students received supplemental reading intervention daily for 50 minutes in small groups from October to April. Students in the comparison condition received the school's existing instructional program for struggling readers. Criteria were established to determine adequate RTI at the end of first grade and at the end of second grade. The results indicated that more students who participated in the first-grade intervention in either Spanish or English met the established RTI standards than students who did not, and this finding was maintained through the end of second grade.     

Socialization of coping with community violence: influences of caregiver coaching, modeling, and family context

A socialization model of coping with community violence was tested in 101 African American adolescents (55% male, ages 9-13) and their maternal caregivers living in high-violence areas of a mid-sized, southeastern city. Participants completed interviews assessing caregiver coping, family context, and child adjustment. Caregiver-child dyads also discussed a film clip depicting community violence. Parental coaching (caregivers' strategies suggesting how to cope) and child-reported coping were coded from the discussion. Coaching, modeling (caregivers' own coping), and family context each contributed to children's coping with violence. Children's problem-focused coping in response to violence had the strongest associations with changes in their adjustment 6 months later. Implications for interventions with youth and families are discussed.     

Color vision in the giant panda (Ailuropoda melanoleuca)

Hue discrimination abilities of giant pandas were tested, controlling for brightness. Subjects were 2 adult giant pandas (1 male and 1 female). A simultaneous discrimination procedure without correction was used. In five tasks, white, black, and five saturations each of green, blue, and red served as positive stimuli that were paired with one or two comparison stimuli consisting of 16 saturations of gray. To demonstrate discrimination, the subjects were required to choose the positive stimulus in 16 of 20 trials (80% correct) for three consecutive sessions. Both subjects reached criterion for green and red. The female subject also reached criterion for blue. The male was not tested for blue. This study is a systematic replication of Bacon and Burghardt’s (1976) color discrimination experiment on black bears. The results suggest that color vision in the giant panda is comparable to that of black bears and other carnivores that are not strictly nocturnal.     

Theory-based model of factors affecting information overload

As the volume of available information increases, individuals and organisations become overwhelmed by the plethora of information. This can reduce productivity and performance, hinder learning and innovation, affect decision making and well-being and cost organisations large amounts of money. This paper develops a new theory-based model of factors affecting information overload and provides a formula for calculating the extent of overload, potentially of use as a diagnostic tool supporting individual or organisational development.     

Benefits of omega‐3 supplementation for schoolchildren: Review of the current evidence

Despite the potential impact nutrition may have on learning, there have been surprisingly few papers published directed towards the educational research community. In contrast, omega‐3 supplementation studies are being frequently cited in the media, leading to parents asking for advice and guidance. The purpose of this article is to review the evidence to date for any effect of using omega‐3 supplementation in school‐aged children. This article focuses on the research that has been undertaken, particularly in relation to behaviour, education and cognitive development, in both typically developing populations as well as in children with specific learning difficulties and developmental disorders. Recommendations for future studies in this area have been highlighted in view of current knowledge. In conclusion, it was found that there is a shortage of properly controlled omega‐3 supplementation trials, particularly with typically developing children, to advocate the supplementation of all children with omega‐3 fatty acids, but due to the known importance of omega‐3 fatty acids in the brain and early development, further research is required.     

Teaching Information Systems Management Skills: Using Integrated Projects and Case Studies

University courses in Computer Science (CS) and Information Systems (IS) are often criticized by industry for concentrating on conceptual learning while failing to provide their students with experience and grounding in managerial skills. This paper describes and discusses an innovative course In this paper the term “course” will be used to refer to a single integrated unit of study. In New Zealand such units are often referred to as “papers”. These courses can be combined together, according to various rules, to form a “course of study” which will lead to a qualification. At Massey University, a degree is comprised of 24 such courses.structure which has been developed in order to ground the teaching of IS management theory in its local context by interlinking practical projects and case studies in local organizations. The student projects are used to generate a large “cross-sectional” case study which describes several IS management problems that are occurring simultaneously in the same organization. Students are required to integrate their analysis of the problems and to recommend an appropriate series of responses which will tackle all the situations. The paper describes the rationale and organization of the course, the results of an evaluation of its effectiveness, and discusses some of the problems that were encountered during its implementation.