Impact of Anatomy Boot Camp on Students in a Medical Gross Anatomy Course

Lincoln Memorial University‐DeBusk College of Osteopathic Medicine (LMU‐DCOM) offers an optional three‐week summer Anatomy Boot Camp course (ABC) to facilitate students' transition into medical school and promote retention of anatomy subject matter. The pre‐matriculation program is a supplemental instruction course that utilizes a small group learning format. Boot camp instruction is led by teaching assistants and two anatomy professors. Enrollees gain early exposure to Medical Gross Anatomy (MGA) course subject matter, which is taught in the fall semester, and learn study skills necessary to excel in medical school. No grade is assigned for the course, therefore participants can study without the fear of potentially affecting grades. This study evaluates the effectiveness of the LMU‐DCOM ABC course using data from four consecutive summers. Independent two‐sample t‐tests were used to compare ABC to non‐ABC students for the following variables: incoming grade point average (GPA) and Medical College Admission Test® (MCAT®) scores, MGA written and laboratory practical examination grades, and final MGA course grade. Additionally, a 26‐question survey was administered to 2012–2014 boot camp participants. There were no significant differences in incoming GPA and MCAT scores. However, boot campers scored significantly higher on the first two lecture and laboratory examinations (P < 0.05) for each year of the study. Thereafter scores varied less, suggesting a faster head start for boot camp participants. Mean MGA final grade was on average 3% higher for the boot camp cohort. The survey feedback supports that the ABC course assists with the academic and social transition into medical school. Anat Sci Educ 10: 215–223. © 2016 American Association of Anatomists.     

Savings test for associations between neutral stimuli

Three experiments showed a savings procedure to be an effective and sensitive alternative to sensory preconditioning procedures as a measure of associations among neutral stimuli. Experiment 1 showed that within-compound associations developed more rapidly in reinforced appetitive serial compound conditioning when nonreinforced preexposure to the serial compound was given than when separate element or no preexposure was given. Experiment 2 showed the savings effect to be highly stimulus specific. Experiment 3 examined the facilitation of serial compound conditioning after either simultaneous or serial nonreinforced preexposure to the elements of the compound. The results of that experiment were consistent with those of analogous sensory preconditioning experiments. When preexposure involved only the two elements of the subsequently reinforced compound, serial preexposure produced more savings than simultaneous preexposure. But when preexposure involved a three-stimulus procedure like that used by Rescorla (1980b), simultaneous preexposure resulted in more savings. Advantages of the savings procedure over sensory preconditioning as a measure of association among neutral stimuli are discussed.     

Size-dependent trajectories of DNA macromolecules due to insulative dielectrophoresis in submicrometer-deep fluidic channels

In this paper, we demonstrate for the first time that insulative dielectrophoresis can induce size-dependent trajectories of DNA macromolecules. We experimentally use λ (48.5 kbp) and T4GT7 (165.6 kbp) DNA molecules flowing continuously around a sharp corner inside fluidic channels with a depth of 0.4 μm. Numerical simulation of the electrokinetic force distribution inside the channels is in qualitative agreement with our experimentally observed trajectories. We discuss a possible physical mechanism for the DNA polarization and dielectrophoresis inside confining channels, based on the observed dielectrophoresis responses due to different DNA sizes and various electric fields applied between the inlet and the outlet. The proposed physical mechanism indicates that further extensive investigations, both theoretically and experimentally, would be very useful to better elucidate the forces involved at DNA dielectrophoresis. When applied for size-based sorting of DNA molecules, our sorting method offers two major advantages compared to earlier attempts with insulative dielectrophoresis: Its continuous operation allows for high-throughput analysis, and it only requires electric field strengths as low as ∼10 V∕cm.     

Truncation error analysis in computing of SEP and SEP floor for partially coherent receiver of MPSK signals over composite fading channels

In this paper, we analyze detection of multilevel phase-shift keying (MPSK) signals transmitted over a Gamma shadowed Nakagami-m fading channel. We derive novel analytical expression, in terms of Meijer’s G function, for Fourier coefficients of the probability density function of the received signal composite phase. Under the assumption of the imperfect reference signal extraction in the receiver, which is performed from the pilot signal, the analytical expression is derived for the symbol error probability (SEP) in the form of convergent series. The existence of the error floor is identified, and expression for its computation is provided. Mathematical proofs for convergence of Fourier series are provided for both SEP and SEP floor, and novel expressions of upper bounds for truncation errors are derived in terms of elementary mathematical functions. The convergence rate of the derived expressions is examined. Numerical results are confirmed independently by Monte-Carlo simulations.     

Rapid mask prototyping for microfluidics

With the rise of microfluidics for the past decade, there has come an ever more pressing need for a low-cost and rapid prototyping technology, especially for research and education purposes. In this article, we report a rapid prototyping process of chromed masks for various microfluidic applications. The process takes place out of a clean room, uses a commercially available video-projector, and can be completed in less than half an hour. We quantify the ranges of fields of view and of resolutions accessible through this video-projection system and report the fabrication of critical microfluidic components (junctions, straight channels, and curved channels). To exemplify the process, three common devices are produced using this method: a droplet generation device, a gradient generation device, and a neuro-engineering oriented device. The neuro-engineering oriented device is a compartmentalized microfluidic chip, and therefore, required the production and the precise alignment of two different masks.     

The dynamics of the impact and coalescence of droplets on a solid surface

A simple experimental setup to study the impact and coalescence of deposited droplets is described. Droplet impact and coalescence have been investigated by high-speed particle image velocimetry. Velocity fields near the liquid-substrate interface have been observed for the impact and coalescence of 2.4 mm diameter droplets of glycerol∕water striking a flat transparent substrate in air. The experimental arrangement images the internal flow in the droplets from below the substrate with a high-speed camera and continuous laser illumination. Experimental results are in the form of digital images that are processed by particle image velocimetry and image processing algorithms to obtain velocity fields, droplet geometries, and contact line positions. Experimental results are compared with numerical simulations by the lattice Boltzmann method.     

Spontaneous Tumor Lysis Syndrome in an Infant: A Case Report

Tumor lysis syndrome has been observed in patients with malignancies with high cellular burden and high cell turnover, tumor sensitive to therapy, especially after initiating medical treatment. It very rarely occurs spontaneously. The case described here is of 6 months male infant who presented with fever since 1 month and loose stools associated with blood since 15 days. The laboratory investigations showed lactate dehydrogenase (LDH) of 6,192 IU/L and serum uric acid 18.2 mg/dl along with pancytopenia. The infant presented with electrolyte abnormalities and renal failure.     

Intersample optimization in a sampled-data control system using the redundancy of a dual-rate system

The present study discusses the design method for controlling a single-input/single-output linear time-invariant dual-rate system, where the sampling interval of the plant output is longer than the holding interval of the control input. In such a dual-rate system, the intersample output might oscillate even when the sampled output converges to the reference input in the steady state. In a conventional ripple-free method, an existing control law is extended by introducing an exogenous variable, which is independent of the discrete-time sampled response, and the exogenous variable is designed for eliminating the steady-state intersample ripples without changing the existing sampled response. In another method, since a control law is designed such that the intersample performance is optimized, the intersample ripples are eliminated in the transient as well as steady states. However, the preservation of an existing sampled response is not taken into account. The present study proposes a new design method for eliminating the intersample ripples subject to the existing sampled response. In the proposed method, the continuous-time index is optimized subject to the existing discrete-time response. As a result, the intersample ripples are eliminated in the transient as well as steady states, and the existing discrete-time sampled response is maintained. The proposed method is compared to the conventional dual-rate design methods in numerical examples, and the effectiveness of the method is demonstrated.     

A heuristic hierarchical scheme for academic search and retrieval

We present PubSearch, a hybrid heuristic scheme for re-ranking academic papers retrieved from standard digital libraries such as the ACM Portal. The scheme is based on the hierarchical combination of a custom implementation of the term frequency heuristic, a time-depreciated citation score and a graph-theoretic computed score that relates the paper’s index terms with each other. We designed and developed a meta-search engine that submits user queries to standard digital repositories of academic publications and re-ranks the repository results using the hierarchical heuristic scheme. We evaluate our proposed re-ranking scheme via user feedback against the results of ACM Portal on a total of 58 different user queries specified from 15 different users. The results show that our proposed scheme significantly outperforms ACM Portal in terms of retrieval precision as measured by most common metrics in Information Retrieval including Normalized Discounted Cumulative Gain (NDCG), Expected Reciprocal Rank (ERR) as well as a newly introduced lexicographic rule (LEX) of ranking search results. In particular, PubSearch outperforms ACM Portal by more than 77% in terms of ERR, by more than 11% in terms of NDCG, and by more than 907.5% in terms of LEX. We also re-rank the top-10 results of a subset of the original 58 user queries produced by Google Scholar, Microsoft Academic Search, and ArnetMiner; the results show that PubSearch compares very well against these search engines as well. The proposed scheme can be easily plugged in any existing search engine for retrieval of academic publications.