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701.
702.
Chandana Das V. Senthil Kumar Sayantani Basak Surabhi Gupta Sunesh Kumar 《Indian journal of clinical biochemistry : IJCB》2000,15(1):60-62
A female patient who had two primary cancers was investigated. Biochemical analysis of patient's serum for different parameters
indicated an alteration in the metabolic process. Prognostically, the patient has shown favourable clinical features. 相似文献
703.
In this study, we demonstrate a new perspective on in vitro assessment method for evaluating quantum dot (QD) toxicity by using microfluidics technology. A new biomimetic approach, based on the flow exposure condition, was applied in order to characterize the cytotoxic potential of QD. In addition, the outcomes obtained from the flow exposure condition were compared to those of the static exposure condition. An in vitro cell array system was established that used an integrated multicompartmented microfluidic device to develop a sensitive flow exposure condition. QDs modified with cetyltrimethyl ammonium bromide∕trioctylphosphine oxide were used for the cytotoxicity assessment. The results suggested noticeable differences in the number of detached and deformed cells and the viability percentages between two different exposure conditions. The intracellular production of reactive oxygen species and release of cadmium were found to be the possible causes of QD-induced cytotoxicity, irrespective of the types of exposure condition. In contrast to the static exposure, the flow exposure apparently avoided the gravitational settling of particles and probably assisted in the homogeneous distribution of nanoparticles in the culture medium during exposure time. Moreover, the flow exposure condition resembled in vivo physiological conditions very closely, and thus, the flow exposure condition can offer potential advantages for nanotoxicity research. 相似文献
704.
Pradyumna Kumar Mishra A. Bhargava R. P. Punde N. Pathak P. Desikan A. Jain S. Varshney K. K. Maudar 《Indian journal of clinical biochemistry : IJCB》2010,25(2):158-163
The present study included three groups: (A) age and gender matched control (n=24) with no previous signs of M. tuberculosis
complex (MTBC) infection, (B) patients (n=28) diagnosed with gastro-intestinal TB (GITB), (C) patients (n=50) with clinical
and histo-pathological signs of GITB, but were culture and AFB negative. Real time assay performed using fluorescence resonance
energy transfer hybridization probes showed a positivity index of 36 % in group C, i.e. 18 were found reactive from the total
50 cases studied. In addition, immune characterization of these 18 cases showed depleted CD4+ count and increased levels of IFN-γ and TNF-α cytokines. No positive case was found in group A, while in group B, out of
total 28 cases studied 27 were found positive. A combinatorial diagnostic approach for rapid detection and characterization
of GITB might provide specific therapeutic strategies for prevention and treatment of the infection in future. 相似文献
705.
Sunil Kumar Nanda D. R. Suresh A. Vamseedhar K. Pratibha B. Arjun 《Indian journal of clinical biochemistry : IJCB》2010,25(2):213-216
Alkaptonuria, a rare inborn error of tyrosine metabolism, characterized by the absence of homogentisic acid oxidase results
in the accumulation of homogentisic acid in the body. Associated renal failure and cerebral infarction is rare and usually
occurs in the later stages of the disease. We report a 55-year-old male who presented, initially with features of stroke and
degenerative arthritis. He had pigmentation of sclerae, darkening of urine on long standing, abnormal renal profile, degenerative
arthritis and cerebral infarction. Alkaptonuria was suspected and biochemical tests confirmed mild renal impairment, homogentisic
acid in urine and homogentisic acid crystal was detected cytologically in urine sediment. Such a case of Alkaptonuric ochronosis
with cerebrovascular and renal complications have been rarely reported in the previous literature. 相似文献
706.
707.
Gordeeva Tamara Sheldon Kennon Sychev Oleg 《European Journal of Psychology of Education - EJPE》2020,35(1):21-48
European Journal of Psychology of Education - Optimistic attributional style has been shown to be reliably associated with high well-being and low depression and (Hu et al., Journal of Social and... 相似文献
708.
The Urban Review - Teachers do not often have opportunities to openly examine and discuss issues of racism, power, and white privilege. In fact, as Lisa Delpit and other educators have pointed out,... 相似文献
709.
710.
Krishan Kumar 《Higher Education Quarterly》1979,34(1):5-28
All labour is directed towards producing some effect. For though some exertions are taken merely for their own sake, as when a game is played for amusement, they are not counted as labour. We may define labour as any exertion of mind or body undergone partly or wholly with a view to some good other than the pleasure derived directly from the work. 相似文献