Flipping the classroom to teach systematic reviews: the development of a continuing education course for librarians

Objective:The researchers used the flipped classroom model to develop and conduct a systematic review course for librarians.Setting:The research took place at an academic health sciences library.Method:A team of informationists developed and conducted a pilot course. Assessment informed changes to both course components; a second course addressed gaps in the pilot.Conclusion:The flipped classroom model can be successful in developing and implementing a course that is well rated by students.     

城市创新生态系统评价指标探索

开展城市创新生态系统的评价可以更好地把握城市创新生态系统的发展方向和水平, 从而进行科学、合理 的决策。对评价的指标体系进行框架研究,我们是建立在生态学的理论基础之上的,通过NDMEFE模型分析,从活力 动力系统、自组织系统、平衡系统的几个维度,探讨适合生态化的城市创新驱动发展特点的评价指标体系框架,并对 上海创新生态系统评价进行展望,提出建议。     

从《京华烟云》中译本看张振玉的翻译思想

张振玉是一位杰出的台湾翻译家。他翻译的林语堂长篇小说《京华烟云》受到广泛的欢迎。在语言风格上,张振玉巧妙地运用白话文和文言文,文而不古,白而不俗;文化策略上张振玉不仅翻译出原文写明的事物,还补充了没有写明的事物,曲尽原意,并且删略了原文的纯解释性文字。试借《京华烟云》,来初步探析张振玉的翻译思想。     

独立学院艺术专业大学英语教学改革新思路

拟从独立学院艺术专业大学英语教学现状入手,说明了在独立学院艺术专业实行大学英语分级教学改革的必要性,并以大连理工大学城市学院艺术专业大学英语分级教学改革为蓝本,剖析了实行分级教学改革过程中出现的问题,提出任务型教学法和以内容为依托的教材编写方案。希望社会各界更多地关注高校艺术专业大学英语教学,在教学改革、教材编写上予以支持。     

RFID技术在起重机检验中的应用探讨

首先对RFID技术进行了介绍,包括其定义、组成及工作原理,然后对其应用现状进行了阐述。最后结合特种设备中的起重机检验,对RFID技术在特种设备检验中的应用进行了探讨。     

Ds-echinoside A, a new triterpene glycoside derived from sea cucumber, exhibits antimetastatic activity via the inhibition of NF-κB-dependent MMP-9 and VEGF expressions

Ds-echinoside A (DSEA), a non-sulfated triterpene glycoside, was isolated from the sea cucumber Pearsonothuria graeffei. In vitro and in vivo investigations were conducted on the effects of DSEA on tumor cell adhesion, migration, invasion, and angiogenesis. In this study, we found that DSEA inhibited the proliferation of human hepatocellular liver carcinoma cells Hep G2, with a half-maximal inhibitory concentration (IC₅₀) of 2.65 μmol/L, and suppressed Hep G2 cell adhesion, migration, and invasion in a dose-dependent manner. DSEA also reduced tube formation of human endothelial cells ECV-304 on matrigel in vitro and attenuated neovascularization in the chick embryo chorioallantoic membrane (CAM) assay in vivo. Immunocytochemical analysis revealed that DSEA significantly decreased the expression of matrix metalloproteinase-9 (MMP-9), which plays an important role in the degradation of basement membrane in tumor metastasis and angiogenesis. DSEA also increased the protein expression level of tissue inhibitor of metalloproteinase-1 (TIMP-1), an important regulator of MMP-9 activation. From the results of Western blotting, the expressions of nuclear factor-kappa B (NF-κB) and vascular endothelial growth factor (VEGF) were found to be remarkably reduced by DSEA. These findings suggest that DSEA exhibits a significant antimetastatic activity through the specific inhibition of NF-κB-dependent MMP-9 and VEGF expressions.     

Polyethylenimine-cyclodextrin-tegafur conjugate shows anti-cancer activity and a potential for gene delivery

Polyethylenimine-cyclodextrin-tegafur (PEI-CyD-tegafur) conjugate was synthesized as a novel multifunctional prodrug of tegafur for co-delivery of chemotherapeutic agent tegafur and enhanced green fluorescent protein (EGFP) reporter plasmid DNA. Conjugation of tegafur to PEI-CyD via chemical linkage was characterized by ¹H NMR spectrometry and ultraviolet (UV) spectrometry. PEI-CyD-tegafur was able to condense plasmid DNA into complexes of around 150 nm with positive charge at the N/P ratio of 25, in accordance with electron microscopy observation of compact and monodisperse nanoparticles. The results of in vitro experiments showed enhanced cytotoxicity and considerable transfection efficiency in B16F10 cell line. Therefore, PEI-CyD-tegafur may have great potential as a co-delivery system with anti-cancer activity and potential for gene delivery.     

#MeToo,sexual harassment: an article,a forum,and a dream for the future

#MeToo has breathed new life into the women’s movement and especially into understanding and rectifying sexual harassment, abuse and assault. It has galvanized activists around the globe. And it has placed thousands of stories of the harassed in full view of the public. Sexual harassment, abuse and assault may occur within the organizational context or beyond; but sexual harassment, in particular has been legally labeled an organizational phenomenon. With this in mind, Robin Clair frames the early part of this article around the most recent organizational communication theories (see the appendix for an overview of these theories). Following the essay is a forum, in which invited scholars address questions related to the #MeToo movement.     

Lumped parameter model for resonant frequency estimation of a thermoacoustic engine with gas-liquid coupling oscillation

Gas-liquid coupling oscillation is a novel approach to reducing the resonant frequency and to elevating the pressure amplitude of a thermoacoustic engine. If a thermoacoustic engine is used to drive low-frequency pulse tube refrigerators, the frequency matching between the thermoacoustic engine and the refrigerator plays an important role. Based on an acoustic-electric analogy, a lumped parameter model is proposed to estimate the resonant frequency of a standing-wave thermoacoustic engine with gas-liquid coupling oscillation. Furthermore, a simplified lumped parameter model is also developed to reduce the computation complexity. The resonant frequency dependence on the mean pressure, the gas space volume, and the water column length is computed and analyzed. The impact of different working gases on the resonant frequency is also discussed. The effectiveness of the models is validated by comparing the computed results with the experimental data of the gas-liquid coupling oscillation system. An increase in the mean working pressure can lead to a rise in the resonant frequency, and a lower resonant frequency can be achieved by elongating the liquid column. In comparison with nitrogen and argon, carbon dioxide can realize a lower frequency due to a smaller specific heat ratio.