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51.
Martin Meyer 《Research Policy》2006,35(10):1646-1662
This paper explores the relationship between scientific publication and patenting activity. More specifically, it examines for the field of nano-science and nano-technology whether researchers who both publish and patent are more productive and more highly cited than their peers who concentrate on scholarly publication in communicating their research results. This study is based on an analysis of the nano-science publications and nano-technology patents of a small set of European countries. While only a very few nano-scientists appear to hold patents in nano-technology, many nano-inventors seem to be actively publishing nano-science research. Overall, the patenting scientists appear to outperform their solely publishing (non-inventing) peers in terms of publication counts and citation frequency. However, a closer examination of the highly active and highly cited nano-authors points to a slightly different situation. While still over-represented among the highly cited authors, inventor-authors appear not to be among the most highly cited authors in that category, with a single notable exception. One policy implication is that, generally speaking, patenting activity does not appear to have an adverse impact on the publication and citation performance of researchers.  相似文献   
52.
Longitudinal course of rapid naming in disabled and nondisabled readers   总被引:1,自引:0,他引:1  
The Rapid Automatized Naming Test (Denckla and Rudel 1974) was studied cross-sectionally in an sample of kindergartners (n=342) at-risk for reading disability (Study 1), and longitudinally in an n=160 epidemiological normal sample of children tested in first, third, fifth, and eighth grades (Study 2). Study 1 showed faster absolute naming speeds for those with near perfect untimed alphabet recitation, but the stronger and more orderly relation (at r=.31, p<.0001) was between three levels of alphabet recitation accuracy and the relative number/letter naming speed advantage (ratio of mean number/letter naming speed minus mean color/object naming speed over mean color/object naming speed). In Study 2, the number/letter advantage was already strongly present by first grade, and did not increase significantly thereafter, but absolute naming times improved steadily across grades in an exponential decay function. In this sample, the relative number/letter advantage was not related to reading level. However, the absolute color/object naming speed was strongly related to reading level and vocabulary across grades. Norms for the Rapid Automatized Naming Test based on the epidemiological normal sample tested in Grades 1, 3, 5, and 8 are presented in the appendix.  相似文献   
53.
Building on recent breakthroughs in the field of microfluidic-based capture of rare cancer cells circulating in the blood, the present article reports on the use of Herceptin functionalized PDMS devices designed to efficiently capture from blood cancer cells, overexpressing the tyrosine kinase human epidermal growth factor receptor (HER2). The identification of patients overexpressing HER2 is critical as it typically associates with an aggressive disease course in breast cancer and poor prognosis. Importantly, HER2 positive patients have been found to significantly benefit from Herceptin (Trastuzumab), a humanized monoclonal antibody (MAb) against HER2. Disposable PDMS devices prepared using standard soft lithography were functionalized by the plasma polymerization of an epoxy-containing monomer. The epoxy-rich thin film (AGEpp) thus created could be conjugated with Herceptin either directly or through a polyethylene glycol interlayer. The properties and reactivity toward the monoclonal antibody conjugation of these coatings were determined using x-ray photoelectron spectroscopy; direct conjugation provided a good compromise in reactivity and resistance to biologically nonspecific fouling and was selected. Using the breast cancer cell line SK-BR-3 as a model for cells overexpressing HER2, the immunocapture efficacy of the Herceptin functionalized PDMS was demonstrated in model studies. Validation studies confirmed the ability of the device to efficiently capture (~80% capture yield) HER2 positive cells from full blood.  相似文献   
54.
During competition, kayak athletes must optimally adapt to environmental factors (e.g. wind, waves) to achieve peak performance. However, the ability to adapt to such perturbations has never been assessed in kayak paddling. Therefore, the aim of the current study was to evaluate the local dynamic stability in sports technique of youth sprint kayak athletes. In a cross-sectional study, 14 healthy male athletes were recruited from an elite youth sprint kayak squad. During an incremental kayak ergometer test, mean power, heart rates and local dynamic technique stability of hands, arms, trunk and paddle were registered and the association with the athletes 2000?m free-water times were estimated using mixed models. The 2000?m free-water performance significantly predicted the paddles (p?=?.037) local dynamic stability whereas no association was found for the trunk or the upper extremity kinematics. In conclusion, kayak athletes with high-performance capability over 2000?m paddling depict high local dynamic technique stability. This emphasizes the importance of a stable technique for advanced kayak skills, especially regarding paddling movements.  相似文献   
55.
While much research has been done to analyze whether socioeconomic status influences prosocial behavior in the form of donations, no consensus has yet emerged in the relevant literature. We contribute to this research by studying, based on a dataset from a questionnaire of volunteers of sports clubs in Palatinate (part of Rhineland–Palatinate, Germany) whether social status affects donations. We measured social status of volunteers of sports clubs along the dimensions income, vocation, education and we considered status crystallization. Results showed that social status has a positive effect on the likelihood of donations. We report similarities and differences across different categories of donations (donations to one’s own sports club, to other clubs, to aid projects, and political parties).  相似文献   
56.
This contribution aims to lay down the theoretical potential of accompaniment as a phenomenon and developing this point further from a pedagogical perspective. The core assumption is that accompaniment represents both a pedagogically relevant phenomenon of action as well as an essential characteristic of the system. In this sense, accompaniment can be understood as creating a possibility for looking at phenomena of education on a micro and a macro level. Thus, the assumption follows that a central signature of the social system – namely that of inclusion – has already been incorporated by the pedagogically organized system of lifelong learning a long time ago. This finding has far-reaching consequences for levelling the hierarchy between different layers of the education and learning systems.  相似文献   
57.
58.
During the Paris Olympic Games of July 1924, there were a series of ‘incidents’ in the fencing competition that became known as the Puliti affair. At the centre of the troubles was the Italian Oreste Puliti. The ‘affair’ had to be discussed by the ‘jury d'honneur’ recently set up by the IOC. Both the IOC and the International Federation were concerned with this issue for four more years. This article uses the Puliti affair to discuss several aspects of nationalism in the mid-1920s: the growing tensions between Fascist Italy and democracies such as Hungary and France, the specific Olympic status of fencing challenged in Paris after three centuries of confrontation between the French and Italian schools of fencing, and ongoing tensions between the IOC and the international federations. Finally, the press perceptions of the incident in various countries are briefly discussed.  相似文献   
59.
60.
To be successful, an instructional video presentation needs to be effective, valued, liked and efficient, and educationalists and designers should strive (explicitly and implicitly) to satisfy these criteria. In the interests of optimum teaching effect, a didactical distinction is recommended between video presentations that have to ‘instruct’, ‘explain’, ‘tell’ and ‘let encounter’. A schema or frame of reference is proposed, the use of which (it is claimed) can help to optimise communication between video producer, teacher and instructional designer  相似文献   
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