Impact of combining data from multiple instruments on performance of patient-based real-time quality control

IntroductionIt is unclear what is the best strategy for applying patient-based real-time quality control (PBRTQC) algorithm in the presence of multiple instruments. This simulation study compared the error detection capability of applying PBRTQC algorithms for instruments individually and in combination using serum sodium as an example.Materials and methodsFour sets of random serum sodium measurements were generated with differing means and standard deviations to represent four simulated instruments. Moving median with winsorization was selected as the PBRTQC algorithm. The PBRTQC parameters (block size and control limits) were optimized and applied to the four simulated laboratory data sets individually and in combination.ResultsWhen the PBRTQC algorithm were individually optimized and applied to the data of the individual simulated instruments, it was able to detect bias several folds faster than when they were combined. Similarly, the individually applied algorithms had perfect error detection rates across different magnitudes of bias, whereas the error detection rates of the algorithm applied on the combined data missed smaller biases. The performance of the individually applied PBRTQC algorithm performed more consistently among the simulated instruments compared to when the data were combined.DiscussionWhile combining data from different instruments can increase the data stream and hence, increase the speed of error detection, it may widen the control limits and compromising the probability of error detection. The presence of multiple instruments in the data stream may dilute the effect of the error when it only affects a selected instrument.     

Information retrieval in the workplace: A comparison of professional search practices

Legal researchers, recruitment professionals, healthcare information professionals, and patent analysts all undertake work tasks where search forms a core part of their duties. In these instances, the search task is often complex and time-consuming and requires specialist expertise to identify relevant documents and insights within large domain-specific repositories and collections. Several studies have been made investigating the search practices of professionals such as these, but few have attempted to directly compare their professional practices and so it remains unclear to what extent insights and approaches from one domain can be applied to another. In this paper we describe the results of a survey of a purposive sample of 108 legal researchers, 64 recruitment professionals and 107 healthcare information professionals. Their responses are compared with results from a previous survey of 81 patent analysts. The survey investigated their search practices and preferences, the types of functionality they value, and their requirements for future information retrieval systems. The results reveal that these professions share many fundamental needs and face similar challenges. In particular a continuing preference to formulate queries as Boolean expressions, the need to manage, organise and re-use search strategies and results and an ambivalence toward the use of relevance ranking. The results stress the importance of recall and coverage for the healthcare and patent professionals, while precision and recency were more important to the legal and recruitment professionals. The results also highlight the need to ensure that search systems give confidence to the professional searcher and so trust, explainability and accountability remains a significant challenge when developing such systems. The findings suggest that translational research between the different areas could benefit professionals across domains.