Modulation of an activity response with associative and nonassociative fear in the rat: A lighting differential influences the form of defensive behavior evoked after fear conditioning

Rats confronted with the onset of a light gradient display a transient increase in locomotion called theactivity response (AR) and a dark preference (Godsil & Fanselow, 2004). These experiments demonstrate that the magnitude of the AR can be blunted with Pavlovian fear-conditioning procedures via associative and nonassociative fear. Although manifested in decreased locomotion, the blunted AR effect was not due to increased freezing or immobility behaviors. Instead, rats displayed reduced rearing and an increase in a class of behaviors calledstationary activity. These results suggest that the lighting differential supplied by the cue influences the topography of defensive behavior and reduces the expression of freezing. This procedure provides a means by which to examine learned and unlearned defensive responses to the same stimulus.     

An empirical investigation of factors influencing the adoption of data mining tools

Previous studies explored the adoption of various information technologies. However, there is little empirical research on factors influencing the adoption of data mining tools (DMTs), particularly at an individual level. This study investigates how users perceive and adopt DMTs to broaden practical knowledge for the business intelligence community. First, this study develops a theoretical model based on the Technology Acceptance Model 3, and then examines its perceived usefulness, perceived ease of use, and its ability to explain users’ intentions to use DMTs. The model's determinants include 4 categories: the task-oriented dimension (job relevance, output quality, result demonstrability, response time, and format), control beliefs (computer self-efficacy and perceptions of external control), emotion (computer anxiety), and intrinsic motivation (computer playfulness). This study also surveys the moderating effect of experience and output quality on the determinants of DMT adoption and use. An empirical study involving 206 DMT users was conducted to evaluate the model using structural equation modeling. Results demonstrate that the proposed model explains 58% of the variance. The findings of this study have interesting implications with respect to DMT adoption, both for researchers and practitioners.     

Study of C-Reactive Protein and Myocardial Infarction in the Indian Population

To analyse the association of high sensitivity C-reactive (hsCRP) protein levels and −717A/G single nucleotide polymorphism of CRP with acute myocardial infarction (AMI) in the Indian population. Study population included 100 MI cases wherein 32 patients had experienced previous MI (MI-Group-1), 68 MI cases were recruited at presentation (MI-Group-2) and equal number of age and gender matched healthy individuals. hsCRP levels were determined by ELISA and genotyping of −717A/G was carried out by polymerase chain reaction-based restriction digestion method. The −717A/G genotypes did not influence hsCRP level and their distribution did not differ between groups. However, in the present study hsCRP demonstrated significant correlation with BMI in controls of both the genders and with triglycerides in females of AMI at presentation who otherwise are with low risk profile. Identifying traditional risk factors associated with inflammation may help in controlling the acute event.     

A Comparative Study of Bone Scan Findings and Serum Levels of Tumor Marker CA15-3 in Patients with Breast Carcinoma

Breast cancer is one of the most frequent malignancies in the world. Available staging procedures to detect breast cancer are bone scan, chest X-ray, liver ultrasonography, computerized tomography, estimation of tumor markers like carbohydrate antigen (CA15-3) and carcino embryonic antigen. These procedures are expensive and may not be required in all cases. Out of 70 patients studied, 55 had normal CA15-3 and 15 had elevated levels of Ca15-3. Eight (14.5%) of the 55 patients with normal CA15-3 had abnormal bone scan. Fifteen patients had CA15-3 levels above the normal range and among these 9 (60%) had abnormal bone scan. While prime facie it would appear that a high level of CA15-3 correlate with abnormal bone scan, it is also true that the numbers are small at present and conclusions about the validity of CA15-3 as marker of bone metastasis may be premature.     

纽约大学入学申请书

我是精力旺盛的家伙--爬墙和砸冰,小菜一碟.我远近闻名,因为有次我利用午休时间,改造了火车站,提高了候车室保温效果.我为古巴难民逐条翻译骂人的脏话.我写过歌剧,并且还得了奖.我的工作效率很高.有时,我可以连续三天踩水.     

Current status and development of percutaneous coronary intervention in China

##正##Dr.Gruntzig et al.(1979) successfully completed the world's first percutaneous coronary intervention (PCI),a percutaneous transluminal coronary