The network of innovators in Jena: An application of social network analysis

We apply social network analysis methods to describe the evolution of the innovator network of Jena, Germany in the period from 1995 to 2001. We find this evolution to be directed towards an increasing focus on core competencies of the network. Further we analyse the network resulting from R&D cooperations and explain - by means of network regression techniques - that the job mobility of scientists and the technological overlap between the actors, rather than past cooperations, can best predict the resulting structure.     

An empirical test of stage models of e-government development: Evidence from Dutch municipalities

In this article we empirically test stage models of e-government development. We use Lee's classification to make a distinction between four stages of e-government: informational, requests, personal, and e-democracy. We draw on a comprehensive data set on the adoption and development of e-government activities in 510 Dutch municipalities over the period 2004–2009. Our results show that progression through stages of e-government is mostly linear. However, it seems that a single dimension is insufficient to explain e-government development at the level of more specific features of e-government. Our analysis demonstrates that municipalities sometimes adopt certain e-government features at a later stage even if features of an earlier stage are not adopted at all. These findings suggest that municipalities can—at the level of e-government features—immediately proceed to later stages without having to pass through earlier stages. We conclude that stage models may have some value for benchmarking municipalities at the level of stages, but are inadequate in explaining or predicting the development of features at the different e-government stages.     

Towards state‐mandated testing in Germany: how do teachers assess the pedagogical relevance of performance feedback information?

The paper analyses how teachers view state‐mandated tests in Baden‐Württemberg, a large state in the south‐west of Germany. For the first time in 2006, public secondary schools were bound by law to administer Vergleichsarbeiten [state‐wide tests] in up to three relevant subjects after Grade 6. Scholars in the field of school improvement emphasise that there is a gap between performance feedback provided by external tests and how this information is internally processed. To bridge this gap, a crucial precondition is that teachers must accept state‐wide testing as a useful instrument for improving the performance of schools. To examine how teachers view the pedagogical relevance of performance feedback information, 256 secondary schools were approached, and an anonymous questionnaire was completed by a representative sample of 307 teachers with Grade 6 classes. Analysis of the quantitative data reveals that teachers in general secondary schools (the lower level of the academically streamed secondary system) are more open‐minded towards the tests than their colleagues in intermediate schools or in grammar schools (the highest level). Even so, only a small percentage of teachers in general secondary schools acknowledge the pedagogical relevance of performance feedback information for improving teaching strategies. This result suggests that state‐mandated testing in Baden‐Württemberg is highly unlikely to initiate or support school improvement activities for the time being.     

Injuries in formal and informal non-professional soccer – an overview of injury context,causes, and characteristics

The objective of this study is to analyse context, causes, and characteristics of injuries in non-professional soccer. Therefore, a retrospective telephone survey was carried out with persons who were injured while playing soccer and who reported this accident to the Swiss National Accident Insurance Fund (Suva). Based on these data, an analysis of 708 soccer injuries was performed. The findings show that 30.1% of the injuries occurred during informal soccer play, and 75.4% of the injured persons were soccer club members. 53.0% of all injuries were caused by contact and 29.5% by foul play. Foul play was not associated with injury severity. With respect to injury severity, twisting/turning and being tackled by an opponent were identified as the most influental injury causes. Moreover, the risk of being severely injured was particularly high players of the 30+/40+ amateur leagues. In conclusion, the findings highlight that 30+/40+ league players are a major target group for the prevention of severe soccer injuries. Soccer clubs may constitute an appropriate multiplier for implementing prevention strategies such as fair play education, healthy play behaviours, and prevention programmes. Finally, a better understanding of injury situations leading to severe injuries is needed to improve injury prevention.     

Research on Tai Chi as a sport in health care

This article examines the content and methodology of studies on Tai Chi as a sport in health care. We investigate the concept behind the rather simple name “Tai Chi,” concluding that this concept is manifold and highly variable. How did researchers deal with this variability when studying the effects of Tai Chi as a health-care intervention? We then explore how scientific research on Tai Chi has been conducted to date and draw the interim conclusion that the variability was barely taken into consideration. Our analysis of seven Tai Chi interventions reveals that two interventions referred to as Tai Chi may differ considerably in their content. The variability poses difficulty in repeating the intervention and drawing causal inferences. This problem is discussed in the current literature under the term “complexity in health-care interventions.” On the basis of a summary of this debate, we discuss the challenge of researching Tai Chi from a complex perspective—with the aim of achieving solid results that can be repeated.     

Expression of a fusion protein of human ciliary neurotrophic factor and soluble CNTF-Receptor and identification of its activity

Ciliary neurotrophic factor (CNTF) has pleiotropic actions on many neuronal populations as well as on glia. Signal transduction by CNTF requires that it bind first to CNTF-R, permitting the recruitment of gp130 and LIF-R, forming a tripartite receptor complex. Cells that only express gp130 and LIF-R, but not CNTF-R are refractory to stimulation by CNTF. On many target cells CNTF only acts in the presence of its specific agonistic soluble receptors. We engineered a soluble fusion protein by linking the COOH-terminus of sCNTF-R to the NH₂-terminus of CNTF. Recombinant CNTF/sCNTF-R fusion protein (Hyper-CNTF) was successfully expressed in COS-7 cells. The apparent molecular mass of the Hyper-CNTF protein was estimated from western blots to be 75 kDa. Proliferation assays of transfected BAF/3 cells in response to CNTF and Hyper-CNTF were used to verify the activity of the cytokines. The proliferative results confirmed that CNTF required homodimerization of the gp130, CNTF-R and LIF-R receptor subunit whereas Hyper-CNTF required heterodimerization of the gp130 and LIF-R receptor subunit. We concluded that the fusion protein Hyper-CNTF had superagonistic activity on target cells expressing gp130 and LIF-R, but lacking membrane-bound CNTF-R. Project supported by the Scientific Research Foundation for the Returned Overseas Chinese Scholar, Zhejiang Province, China and SFB415, TP B5, Germany.     

The Independence of Research—A Review of Disciplinary Perspectives and Outline of Interdisciplinary Prospects

Minerva - The independence of research is a key strategic issue of modern societies. Dealing with it appropriately poses legal, economic, political, social and cultural problems for society, which...     

Knowledge transfer by sharing task templates: two approaches and their psychological requirements

This paper considers two paradigms of process-aware information systems (PAIS) that are used to share knowledge about planning and executing tasks. The case-based task management (CBTM) system is based on the transduction of execution protocols, so-called cases; and the pattern-based task management (PBTM) system is based on task patterns that are derived from cases but yield more abstract information. As user motivation to contribute to a collaborative task management system is a crucial factor for its success, we consider the different motivational requirements of CBTM and PBTM from a psychological point of view. Based on experimental findings about different factors that have been shown to enhance people's motivation to contribute their knowledge to a shared pool, we compare the two approaches and assess which one is more appropriate with respect to motivation.