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Knowledge production and scientific research have become increasingly more collaborative and international, particularly in pharmaceuticals. We analyze this tendency in general and tie formation in international research networks on the country level in particular. Based on a unique dataset of scientific publications related to pharmaceutical research and applying social network analysis, we find that both the number of countries and their connectivity increase in almost all disease group specific networks. The cores of the networks consist of high income OECD countries and remain rather stable over time. Using network regression techniques to analyze the network dynamics our results indicate that accumulative advantages based on connectedness and multi-connectivity are positively related to changes in the countries’ collaboration intensity whereas various indicators on similarity between countries do not allow for unambiguous conclusions.  相似文献   
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The Shanghai Institute for Advanced Studies is committed to the outlined goals of the older science academies, but is also trying to look beyond them to find its own course.  相似文献   
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In this paper we present a new fabrication method that combines for the first time popular SU-8 technology and PerMX dry-photoresist lamination for the manufacturing of high aspect ratio three-dimensional multi-level microfluidic networks. The potential of this approach, which further benefits from wafer-level manufacturing and accurate alignment of fluidic levels, is demonstrated by a highly integrated three-level microfluidic chip. The hereby achieved network complexity, including 24 fluidic vias and 16 crossing points of three individual microchannels on less than 13 mm(2) chip area, is unique for SU-8 based fluidic networks. We further report on excellent process compatibility between SU-8 and PerMX dry-photoresist which results in high interlayer adhesion strength. The tight pressure sealing of a fluidic channel (0.5 MPa for 1 h) is demonstrated for 150 μm narrow SU-8/PerMX bonding interfaces.  相似文献   
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News reports (e.g., Abrams, 2008) and scholarly research (e.g., Wiersma & Fife, 2005) have indicated increasing concern that parent-spectator behavior at youth sport events may be problematic. Multiple strategies have been used to influence spectator behavior in youth sport contexts (e.g., "Silent Sundays"). However it is unlikely that interventions aimed at changing parent-spectator behaviors have adequately considered young athletes' perspectives, because little is known about how children want parents to behave during youth sport events. Therefore, children (ages 7-14 years) were asked to describe how parents actually behaved at youth sport events and how they wanted parents to behave. Through grounded theory analysis (Charmaz, 2000), three parent "roles" emerged from the data-supportive parent, demanding coach, and crazed fan.  相似文献   
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