Nonword repetition with spectrally reduced speech: some developmental and clinical findings from pediatric cochlear implantation

Nonword repetition skills were examined in 24 pediatric cochlear implant (CI) users and 18 normal-hearing (NH) adult listeners listening through a CI simulator. Two separate groups of NH adult listeners assigned accuracy ratings to the nonword responses of the pediatric CI users and the NH adult speakers. Overall, the nonword repetitions of children using CIs were rated as more accurate than the nonword repetitions of the adults. The nonword repetition accuracy ratings from both groups of subjects were correlated with open- and closed-set word recognition scores and forward digit spans. Only the perceptual accuracy scores from pediatric CI users were correlated with measures of speech production accuracy. These results suggest that although the pediatric CI users had more experience and success in perceiving speech under degraded auditory conditions, developmental differences in their memory skills prevent them from performing as well on working memory tasks as mature listeners.     

Peer group socialization of homophobic attitudes and behavior during adolescence

A social developmental framework was applied to test for the socialization of homophobic attitudes and behavior within adolescent peer groups (Grades 7-11; aged 12-17 years). Substantial similarity within and differences across groups were documented. Multilevel models identified a group socializing contextual effect, predicting homophobic attitudes and behavior of individuals within the group 8 months later, even after controlling for the predictive effect of individuals' own previously reported attitudes and behavior. Several group characteristics moderated the extent to which individuals' previously reported attitudes predicted later attitudes. Findings indicate the need to integrate the concurrent assessment of individual and social factors to inform the construction of more comprehensive models of how prejudiced attitudes and behaviors develop and are perpetuated.     

Differential contribution of specific working memory components to mathematics achievement in 2nd and 3rd graders

The contribution of the three core components of working memory (WM) to the development of mathematical skills in young children is poorly understood. The relation between specific WM components and Numerical Operations, which emphasize computation and fact retrieval, and Mathematical Reasoning, which emphasizes verbal problem solving abilities in 48 2nd and 50 3rd graders was assessed using standardized WM and mathematical achievement measures. For 2nd graders, the central executive and phonological components predicted Mathematical Reasoning skills; whereas the visuo-spatial component predicted both Mathematical Reasoning and Numerical Operations skills in 3rd graders. This pattern suggests that the central executive and phonological loop facilitate performance during early stages of mathematical learning whereas visuo-spatial representations play an increasingly important role during later stages. We propose that these changes reflect a shift from prefrontal to parietal cortical functions during mathematical skill acquisition. Implications for learning and individual differences are discussed.     

A model for using a concept inventory as a tool for students' assessment and faculty professional development

This essay describes how the use of a concept inventory has enhanced professional development and curriculum reform efforts of a faculty teaching community. The Host Pathogen Interactions (HPI) teaching team is composed of research and teaching faculty with expertise in HPI who share the goal of improving the learning experience of students in nine linked undergraduate microbiology courses. To support evidence-based curriculum reform, we administered our HPI Concept Inventory as a pre- and postsurvey to approximately 400 students each year since 2006. The resulting data include student scores as well as their open-ended explanations for distractor choices. The data have enabled us to address curriculum reform goals of 1) reconciling student learning with our expectations, 2) correlating student learning with background variables, 3) understanding student learning across institutions, 4) measuring the effect of teaching techniques on student learning, and 5) demonstrating how our courses collectively form a learning progression. The analysis of the concept inventory data has anchored and deepened the team's discussions of student learning. Reading and discussing students' responses revealed the gap between our understanding and the students' understanding. We provide evidence to support the concept inventory as a tool for assessing student understanding of HPI concepts and faculty development.     

The essence of information: Philosophical notes

The information approach is practiced to study the Macrocosm (physical reality), biosphere, Microcosm (psychic reality), social reality, spiritual reality, and the technosphere. The ways in which scientists of different specialties understand information are characterized in detail. The interrelations between types of realities and types of information are revealed.     

Personalized context-oriented support for interactions between production networks members

An approach to information support for interactions between production networks members is proposed based on the use of a context-oriented knowledge management system. The use of context makes it possible to provide the production network members with currently relevant knowledge. Managing the profiles of members and users enables the personalization of information support for members in the knowledge management system and allows using them as sources of knowledge.     

Open access to scientific knowledge. Who receives dividends?

Open access to scientific knowledge is considered as a new neo-liberal project in the globalized world. The advantages and disadvantages that members of the open access obtain are described. Open access greatly facilitates monitoring, analysis, and control of scientific research by global institutions and transnational corporations, and enables them to identify promising branches of knowledge on the periphery of the global science system that are obtained outside of the “mainstream” and use them for their interests. The link between open access to scientific knowledge and knowledge feudalism is developed.     

Temporal Trends of Malondialdehyde in Stored Human Plasma

Malondialdehyde (MDA) is widely used as oxidative stress biomarker in biomedical research. Plasma is stored in deep freezers generally till analysis. Effect of such storage on MDA values, which may be variable and prolong, was incidentally observed in the ongoing study which is to estimate oxidative stress with oral iron. Plasma from blood samples of pregnant women (20–30 years age) in third trimester of singleton pregnancy (n = 139), consuming oral iron tablets was stored at −20 °C with intention of MDA estimation, as soon as possible. However logistic problems led this storage for prolonged and variable period (1–708 days). When values of MDA estimated using “Ohkawa” 79 method and readings were plotted against time to check the temporal effect, it showed a hyperbolic curve. Standard deviation (SD) was lowest when samples were tested within 3 weeks time. The samples analyzed within 3 weeks had mean ± SD value of 31.59 ± 26.11 μmol/L, while 123.7 ± 93.97 and 366.5 ± 189.8 μmol/L for samples stored for 1–3 and 4 months to 1 year respectively. Mean ± SD were 539.9 ± 196.8 in the samples store for more than a year. Rate of change in values was also lowest (0.0433 μmol/L/day) in the samples tested within first 3 weeks, which rose to 1.2 μmol/L/day during 3 month’s storage. This rate peaked at storage of 120 days (1.87 μmol/L/day) and fell to 0.502 μmol/L/day in the second year of storage. It is concluded that at −20 °C, only 3 weeks of storage time should be considered valid for fairly acceptable stability in MDA values.