From Genes to Environment: Using Integrative Genomics to Build a “Systems‐Level” Understanding of Autism Spectrum Disorders

Autism spectrum disorders (ASD) are pervasive neurodevelopmental disorders that affect an estimated 1 in 110 individuals. Although there is a strong genetic component associated with these disorders, this review focuses on the multifactorial nature of ASD and how different genome‐wide (genomic) approaches contribute to our understanding of autism. Emphasis is placed on the need to study defined ASD phenotypes as well as to integrate large‐scale “omics” data in order to develop a “systems‐level” perspective of ASD, which in turn is necessary to allow predictions regarding responses to specific perturbations and interventions.     

Short Reports Examining the test: an evaluation of the police Standard Entrance Test in Scotland

This short report describes an evaluation of the instrument used for the selection of future police officers in Scotland – the Standard Entrance Test (SET). The study was commissioned by the Scottish Office and undertaken by the Scottish Council for Research in Education during 1995–6. The authors outline the project, report their main findings and identify groups which may have been disadvantaged. The outcome, a revised test, is currently being piloted with new entrants to the force.     

Relays and relations: tracking a policy initiative for improving teacher professionalism

This paper offers a new way of exploring some of the complexities inherent in attempts by policy makers and others to promote educational change. The focus of this study is on the current drive in education policy to alter the basis of teacher professionalism through the application of principles of lifelong learning to teachers’ professional development. Drawing upon data from two studies of the Chartered Teacher (CT) initiative in Scotland the paper examines the formation of successive transmission points as material relays of relations during the process of implementing this policy objective. It explores how three key discursive elements of a professional standard for accomplished teaching: collaborative action, critical reflection and enquiry, and teacher leadership, were progressively recontextualised during the introduction of CT status in schools. The findings indicate some of the conceptual and political struggles involved at the critical junctures where policy implementation requires the movement of a discourse from one social context to another. The paper suggests that a discursive analysis of how a centrally mandated initiative is transmitted can help to promote an understanding of the complexities of this process and increase critical awareness of the issues at stake for those involved.     

Reading disability in boys and girls: No evidence for a differential genetic etiology

In order to test the hypothesis that genetic influences are moreimportant as a cause of reading disability in girls than in boys,composite reading performance data from identical and fraternal twinpairs were analyzed using both concordance and multiple regressionmethods. The sample included 206 identical (99 male, 107 female), 159same-sex fraternal (90 male, 69 female), and 117 opposite-sex fraternaltwin pairs, in which at least one member of each pair had readingdifficulties. Although the difference between the concordance rates forreading disabilities in female identical and same-sex fraternal twinpairs was somewhat greater (65% for identical twins vs.32% for fraternal twins) than the difference in concordance ratesfor boys (68% vs. 39%), loglinear analysis of thesecategorical data revealed that the interaction between sex, zygosity,and concordance was not significant (p > 0.70). Moreover,the heritability of reading disability(h ² _g) estimated from regression analysisof the reading performance data in males was nearly identical to that infemales (h ² _g = 0.58 and 0.59,respectively; p > 0.90). Thus, results of this studyprovide little or no evidence for the hypothesis of greater geneticinfluence on reading difficulties in girls than in boys.     

ICTs in the Rush Hour of Life

In the Netherlands, many women have entered the labor market in the last two decades. This development - among other social changes - has resulted in substantial shifts in the time that Dutch people spend on paid labor and "caring tasks" on the one hand and leisure activities on the other hand. This task combination has caused serious time pressure and coordination problems among dual-income families with children. Therefore, it is not an exaggeration to label this stage of life as the "rush hour of life". In this article the findings of a small-scale qualitative case study among these "busy" households are presented. The objective of this study is to describe and analyze patterns of acceptance and use of information and communication technologies (ICTs), especially telecommunication technologies, in the context of the everyday life of these households. The question is raised whether ICTs can be a solution to time pressure and coordination problems. Theoretically, the research is rooted in a user-oriented perspective toward technological innovation, developed in the United Kingdom by Silverstone, Haddon, and others, which understands the incorporation of ICTs into the everyday life of households as a "domestication process". A paradoxical conclusion of this study is that ICTs are not explicitly perceived as solutions to the communication and coordination problems these households experience in everyday life, although they are being used for solving these problems. This ambiguity seems characteristic for the acceptance of ICTs in everyday life. The domestication concept is a useful concept to describe these ambivalent and paradoxical processes of (non)acceptance and use.     

Young adults’ contact experiences and attitudes toward aging: age salience and intergroup anxiety in South Korea*

From the theoretical perspectives of communication accommodation and intergroup contact, this study examined South Korean young adults’ (N?=?301) perceptions of their communication experiences with a frequently-contacted grandparent, as well as attitudes toward older adults and own aging. Findings from structural equation modeling indicated that the participants’ attitudes towards older adults were positively predicted by contact frequency with the grandparent and negatively predicted by perceptions of the grandparent’s non-accommodative communication. Analyses of indirect effects revealed that young adults’ intergroup anxiety explained these associations. Although the direct effects of contact frequency and the grandparent’s non-accommodation on attitudes toward own aging were nonsignificant, the indirect effects through intergroup anxiety were significant. Moderation analysis indicated that these direct and indirect associations between non-accommodation and aging attitudes were significant only when age salience was low – a finding contrary to existing theory and research. Results are discussed in terms of intergenerational communication and culture, and theories of intergroup contact.     

Imprinting in older ducklings: Some tests of a reinforcement model

Ducklings (Anas Platyrhynchos domesticus) older than the so-called critical period (Days 1 and 2 posthatch) were exposed to an imprinting stimulus after various experimental histories. The first study found that in previously isolated 10-day-old subjects the stimulus exhibited the same capacity to reinforce an operant response and to generate a burst-like pattern of responding as in ducklings imprinted to it on Day 1. In Experiment 2, an imprinting stimulas exhibited reinforcing capacities in 5 to 10-day-old ducklings that had previously been imprinted to a different stimulus. Most of these ducklings came to prefer the second imprinting stimulus over the first. Experiment 3 revealed that in 5-day-old ducklings with a prior history of imprinting to a different stimulus, the otherwise neutral features of a new imprinting stimulus acquired the same kind of persistent control over distress vocalization that they acquire in younger, naive subjects. In all these studies, the only difference between imprinting in older vs. younger subjects was that in older subjects a novel imprinting stimulus initially evoked fear reactions rather than filial behavior. These findings contradict the traditional view of imprinting as an irreversible process that occurs only during a brief critical period, but are entirely consistent with a reinforcement model of imprinting.     

Differentiation and its Problems: the views of primary teachers and curriculum support staff in Northern Ireland

This paper identifies a range of problems associated with putting differentiation into practice. The opinions of head teachers, subject co‐ordinators, and teachers were sought, as well as those of the curriculum support staff in the Education and Library Boards on the extent to which these problems affected primary schools in Northern Ireland, and case‐studies illuminated these views. The results showed that the curriculum support staff regarded most problems in differentiation in a more serious light than the schools themselves did, but there was agreement on the acute lack of time to deliver a differentiated curriculum, on the shortage of human resources and on the difficulties with new assessment methods.     

‘Reflective co-education’ or male-oriented physical education? Teachers' views about activities in co-educational PE classes at German secondary schools

As much as the principle of co-education may appear to make sense in physical education (PE) lessons, trends in its development have emerged over the past years, especially in secondary schools, which were certainly not intended by the pedagogical programme of ‘reflective co-education’, which stands for respect for equality and difference in co-educational PE classes. Although this programme has been anchored in the curricula of various federal states in Germany for around 15 years, the prevailing practice even today, and documented in many empirical studies, is that so-called ‘male-oriented’ activities (e.g. games) predominate in PE classes while ‘female-oriented’ activities (e.g. dance, aerobics, gymnastics or health-related exercises) are scarcely ever taught. The purpose of this contribution is to examine (1) the extent to which male (as well as female) PE teachers actually make such a one-sided selection of activities; (2) the reasons they give for this practice and the way they perceive and judge it; and (3) how they communicate this selection to each other and to their pupils. Seventy-one PE teachers (of both sexes) were asked about these questions in problem-centred interviews. The main result of the study is that both male and female PE teachers almost exclusively do ‘male-oriented’ activities (like games and other competitive activities) in mixed-gender classes, although they give different reasons for doing so. By contrast, so-called ‘female activities’ are avoided. The observable implications are that PE lessons have increasingly become dominated by male patterns of physical activity and that a hierarchy is constructed between so-called ‘male activities’ and ‘female activities’ in PE. As a result, a key objective of ‘reflective co-education’ has not been achieved. Female PE teachers suffer considerably under these conditions. It can be observed that many of them are either planning to reduce their hours in, or even give up, teaching PE (or have already done so).