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Priti Chaturvedi Vinit Mehrotra Yogesh Saxena Soumen Manna 《Indian journal of clinical biochemistry : IJCB》2018,33(3):322-327
Nitric oxide (NO) is one of the key players in the pathogenesis of ischemic stroke. Limited reports are available about the serum level of NO and their correlation with Glasgow Coma Scale (GCS) score in acute (<24 h) ischemic stroke (AIS) patients. A hospital based, cross sectional study was done in North Indian population to find out correlation of serum NO and GCS in AIS patients. 50 patients of AIS and 25 healthy controls were chosen for the study. Serum NO level was measured by ELISA and GCS scores were assessed by a neurologist. Pearson correlation coefficients were analyzed to look for the relationship between NO and GCS. Statistically highly significant elevation in mean serum NO level was observed in cases as compared to controls (p < 0.01). A negative correlation of NO levels with neurological score of GCS r (48) = ?0.144, p > 0.05 was seen. This indicates oxidative stress in acute ischemic stroke may be the result of imbalance in oxidant/antioxidant homeostasis. 相似文献
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Sarita Chavan Laxmayya Sava Vishal Saxena Sandhya Pillai Alka Sontakke Digamber Ingole 《Indian journal of clinical biochemistry : IJCB》2005,20(1):150-152
Glutathione, the dominant intracellular thiol, plays an important protective role against oxidative stress. The accidental
findings of increased reduced glutathione level postprandially as compared to post absorptive level prompted the design of
present study. Reduced Glutathione levels were estimated in 50 healthy individuals in post absorptive and postprandial phase
by taking whole blood in ACD bulb. Mean postprandial reduced Glutathione (9.60±3.39 μmole/gm of Hb) is significantly increased
than mean postabsorptive level (5.53±0.88 μmole/gm of Hb; p<0.001). It also shows positive correlation (r=0.65) between these
two GSH levels. So present study suggests that post absorptive specimen collection is preferable over random or postprandial
as the former reflects the true basal level of reduced glutathione. 相似文献
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Using data from the 2008 University of California Undergraduate Experience Survey, we show that study time and academic conscientiousness
were lower among students in humanities and social science majors than among students in science and engineering majors. Analytical
and critical thinking experiences were no more evident among humanities and social sciences majors than among science and
engineering majors. All three academically beneficial experiences were, however, strongly related to participation in class
and interaction with instructors, and participation was more common among humanities and social sciences students than among
science and engineering students. Bok’s (Our underachieving colleges: A candid look at how much students learn and why they should be learning more. Princeton and Oxford: Princeton University Press, 2006) influential discussion of “underachievement’ in undergraduate education focused on institutional performance. Our findings
indicate that future discussions should take into account differences among disciplinary categories and majors as well. 相似文献