漳平水仙饼茶中酚类提取物的体外抗氧化活性及对小鼠乳腺癌4T1细胞增殖和转移的抑制作用（英文）

目的:探讨不同提取方法所得的漳平水仙饼茶中提取物的主要化学成分、体外抗氧化作用和对小鼠乳腺癌4T1细胞增殖和转移的抑制作用。创新点:首次对漳平水仙饼茶中不同提取物的主要化学成分、体外抗氧化作用和对小鼠乳腺癌4T1细胞增殖和转移的抑制作用进行了研究。方法:以漳平水仙饼茶为原料,利用乙酸乙酯、正丁醇和水分别进行萃取,得到三种提取物。对提取物的茶多酚、黄酮、原花青素、总糖、蛋白质、氨基酸、儿茶素单体、茶黄素、咖啡碱等主要化学成分进行检测。利用DPPH、ABTS和FRAP三种不同方法进一步检测了三种提取物的体外抗氧化性,并评价了提取物对小鼠乳腺癌4T1细胞的增殖、细胞周期、迁移、侵袭等的影响作用。同时,采用皮尔森系数分析和聚类分析两种分析方法探讨了提取物中的化学成分与其抗氧化活性和对4T1细胞作用的相关性。结论:本实验结果显示,漳平水仙饼茶乙酸乙酯层提取物具有最高的茶多酚、黄酮、原花青素和儿茶素单体的含量(表1~3,图1),并且在三种不同的抗氧化体系中均显示出最强的抗氧化性能(表4,图2),同时对小鼠乳腺癌4T1细胞的增殖、细胞周期、迁移、侵袭有非常明显的抑制作用(图3~6)。乙酸乙酯层提取物之所以具有最强的生物活性主要与其含有较多的茶多酚等活性成分有关(表5,图3)。     

LDA模型在专利文本分类中的应用

对传统专利文本自动分类方法中,使用向量空间模型文本表示方法存在的问题,提出一种基于LDA模型专利文本分类方法。该方法利用LDA主题模型对专利文本语料库建模,提取专利文本的文档-主题和主题-特征词矩阵,达到降维目的和提取文档间的语义联系,引入类的类-主题矩阵,为类进行主题语义拓展,使用主题相似度构造层次分类,小类采用KNN分类方法。实验结果：与基于向量空间文本表示模型的KNN专利文本分类方法对比,此方法能够获得更高的分类评估指数。     

第七届农运会对我国新农村体育发展的影响分析

在简要阐述举办农运会意义的基础上,针对当前我国农村体育发展过程中存在的问题,着重分析了农运会对我国新农村体育发展的影响。指出举办农运会将有利于改变农民的体育消费观念,有利于群众体育的进一步普及,有利于进一步强化以人为本的农村体育发展理念。     

高等教育物业管理专业理论课教学内容整体构建研究

本文通过回顾物业管理研究理论,分析了物业管理知识体系与理论教学知识模块,为系统构建高等教育物业管理专业理论课程教学内容体系提出建议。     

浅谈高校国防教育与素质教育的相互关系

国防教育与素质教育具有非常密切的关系。文章探讨了国防教育的主要内容,国防教育在素质教育中的地位和作用,以及加强国防教育的途径。实践证明,加强国防教育有利于促进大学生的素质教育,实现高素质人才的培养。     

德国与美国刑事证据排除规则衍生史及制度构型比较研究

德国证据使用禁止理论与美国非法证据排除规则作为当代世界两大法系主要法治国家在刑事证据排除规则方面的两种代表性理论,在两国的立法和司法实践方面都具有丰富的内涵并按照不同的原则形成了各自的例外。这种"原则加例外"的法律实践模式对于其他法治国家而言具有典型的"范式"意义,这种范式只有在切合各国法律传统和具体国情的基本框架内构建各自的刑事证据排除规则,才能从制度上保障刑事诉讼程序的公正高效运行。     

平谷区农村居民点用地的时空特征及优化布局研究

农村居民点的优化布局必须在分析现状的基础上,按照农村产业发展规划目标,针对不同类型进行分类调控,科学评价农村居民点的综合发展潜力是村庄量化分类的基础,也是协调推进村庄整治的关键所在.本文以北京市平谷区为例,利用2004年、2009年土地利用现状数据库,研究了平谷区2009年农村居民点空间分布特征及2004年-2009年间居民点用地的变化情况.结合山区和平原区的不同发展条件,分别制定山区和平原区农村居民点的综合发展潜力评价指标体系,运用GIS的地理空间分析功能,对评价要素的空间叠加、计算,评价村庄的综合发展潜力.并将评价结果与城镇发展规划相结合,针对农村居民点用地的区位条件,提出居民点用地调控的类型及区域产业发展布局的方向.研究结果体现了土地利用的现状及适宜性,对推进农村居民点整理具有一定的指导意义.     

基于FLowmaster的飞机压力加油系统管路设计仿真

基于某民用飞机压力加油系统设计特点,应用Flowmaster对压力加油系统进行了仿真计算,并通过原理性试验验证,证明计算仿真结果真实有效,能够有效提高压力加油系统研制效率,降低研制成本.文中所提到的仿真计算方法可为其它验证流体管路系统设计提供参考.     

Analysis of repeated high-intensity running performance in professional soccer

Abstract

The aims of this study were twofold: (1) to characterize repeated high-intensity movement activity profiles of a professional soccer team in official match-play; and (2) to inform and verify the construct validity of tests commonly used to determine repeated-sprint ability in soccer by investigating the relationship between the results from a test of repeated-sprint ability and repeated high-intensity performance in competition. High-intensity running performance (movement at velocities >19.8 km · h^?1 for a minimum of 1 s duration) was measured in 20 players using computerized time–motion analysis. Performance in 80 French League 1 matches was analysed. In addition, 12 of the 20 players performed a repeated-sprint test on a non-motorized treadmill consisting of six consecutive 6 s sprints separated by 20 s passive recovery intervals. In all players, most consecutive high-intensity actions in competition were performed after recovery durations ≥61 s, recovery activity separating these efforts was generally active in nature with the major part of this spent walking, and players performed 1.1 ± 1.1 repeated high-intensity bouts (a minimum of three consecutive high-intensity bouts with a mean recovery time ≤20 s separating efforts) per game. Players reporting lowest performance decrements in the repeated-sprint ability test performed more high-intensity actions interspersed by short recovery times (≤20 s, P < 0.01 and ≤30 s, P < 0.05) compared with those with higher decrements. Across positional roles, central-midfielders performed more high-intensity actions separated by short recovery times (≤20 s) and spent a larger proportion of time running at higher intensities during recovery periods, while fullbacks performed the most repeated high-intensity bouts (statistical differences across positional roles from P < 0.05 to P < 0.001). These findings have implications for repeated high-intensity testing and physical conditioning regimens.     

Attentional Patterns Involved in Coping Strategies in a Sport Context

We investigated the relationship between coping strategies and attentional bias after a sport competition. We administered the Ways of Coping Checklist (Paulhan, Nuissier, Quintard, Cousson, & Bourgeois, 1994) to 145 athletes immediately after they had participated in a sport competition. We also assessed attentional bias using a dot probe detection task. Results revealed that emotion-focused coping strategies led athletes to orient their attention away from threat, whereas athletes who adopted problem-focused coping strategies focused their attention toward threat. More precisely, problem-focused coping strategies are related to a facilitated detection of threat, not to disengagement difficulties. The vigilance attentional bias seems to be a compensatory strategy to cope with a stressful situation, such as sport competition.