Managing the Progressive Publishing Company During Market and Technology Transitions

As new media technologies and platforms emerge and take hold in our society, traditional publishers are wondering: What’s in this new content climate for me? The simple answer is: a lot. The digital world, mobile content delivery mechanisms and the public’s increasing comfort—even preference for—a media menu from which they can pick and choose what they want and how they want to receive it, brings exciting and potentially lucrative opportunities. For publishers who understand how to leverage their brand and create authentic, identifiable value in the eyes of the customer, risk can be reduced and new revenue streams built. Here are four best practices to position your publishing company for growth.     

Microfluidic wet spinning of chitosan-alginate microfibers and encapsulation of HepG2 cells in fibers

The successful encapsulation of human hepatocellular carcinoma (HepG2) cells would greatly assist a broad range of applications in tissue engineering. Due to the harsh conditions during standard chitosan fiber fabrication processes, encapsulation of HepG2 cells in chitosan fibers has been challenging. Here, we describe the successful wet-spinning of chitosan-alginate fibers using a coaxial flow microfluidic chip. We determined the optimal mixing conditions for generating chitosan-alginate fibers, including a 1:5 ratio of 2% (w∕w) water-soluble chitosan (WSC) solution to 2% (w∕w) alginate solution. Ratio including higher than 2% (w∕w) WSC solution increased aggregation throughout the mixture. By suspending cells in the WSC-alginate solution, we successfully fabricated HepG2 cell-laden fibers. The encapsulated HepG2 cells in the chitosan-alginate fibers were more viable than cells encapsulated in pure alginate fibers, suggesting that cross-linked chitosan provides a better environment for HepG2 cells than alginate alone. In addition, we found that the adhesion of HepG2 cells on the chitosan-alginate fiber is much better than that on the alginate fibers.     

Identifying the Content,Lesson Structure,and Data Use Within Pre-collegiate Data Science Curricula

Journal of Science Education and Technology - As data become more available and integrated into daily life, there has been growing interest in developing data science curricula for youth in...     

He Knows He Has Wings

何必去管它,人生总是无定？ 有什么关系壮志难成？ 又何必计较你蹉跌并败奔——