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61.
In the quest to create a low-power portable lab-on-a-chip system, we demonstrate the specific binding and concentration of human CD8+ T-lymphocytes on an electrowetting-on-dielectric (EWOD)-based digital microfluidic platform using antibody-conjugated magnetic beads (MB-Abs). By using a small quantity of nonionic surfactant, we enable the human cell-based assays with selective magnetic binding on the EWOD device in an air environment. High binding efficiency (~92%)of specific cells on MB-Abs is achieved due to the intimate contact between the cells and the magnetic beads (MBs) produced by the circulating flow within the small droplet. MBs have been used and cells manipulated in the droplets actuated by EWOD before; reported here is a cell assay of a clinical protocol on the EWOD device in air environment. The present technique can be further extended to capture other types of cells by suitable surface modification on the MBs.  相似文献   
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The specific spatial abilities required for the study of basic structural geology were characterized by quantitative and qualitative data analysis. A geologic spatial ability test (GeoSAT) was developed and administered to 115 comprehensive high-school students. Six of these students were interviewed. An analysis of students' incorrect answers revealed two types of answers: (a) nonpenetrative answers, which were based on external exposures of the structure; and (b) penetrative answers, which indicated attempts at representing internal properties of the structure. Students who tended to give penetrative incorrect answers performed significantly higher than students who tended to give nonpenetrative incorrect answers. The reasoning of students for these types of answers, as determined by interviews, supported the initial assumption that these answers were given by students with different levels of ability mentally to penetrate the image of a structure, which was named visual penetration ability (VPA). The interview findings indicated that the VPA is one of two complementary factors needed to solve the problems of GeoSAT; the other factor is the ability to perceive the spatial configuration of the structure. It is concluded that the teaching and learning process should provide students with assistance in both of these areas. © 1996 John Wiley & Sons, Inc.  相似文献   
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This study deals with engineering education in the middle-school level. Its focus is instructors’ concerns in teaching design, as well as scaffolding strategies that can help teachers deal with these concerns. Through participatory action research, nine instructors engaged in a process of development and instruction of a curriculum about energy along with engineering design. A 50-h curriculum was piloted during a summer camp for 38 middle-school students. Data was collected through instructors’ materials: observation field notes, daily reflections and post-camp discussions. In addition, students’ artifacts and planning graphical models were collected in order to explore how instructors’ concerns were aligned with students’ learning. Findings indicate three main tensions that reflect instructors’ main concerns: how to provide sufficient scaffolding yet encourage creativity, how to scaffold hands-on experiences that promote mindful planning, and how to scaffold students’ modeling practices. Pedagogical strategies for teaching design that developed through this work are described, as well as the ways they address the National Research Council (A framework for K-12 science education: practices, crosscutting concepts, and core ideas. National Academies Press, Washington, DC, 2011) core ideas of engineering education and the International Technological Literacy standards (ITEA in Standards for technological literacy, 3rd edn. International Technology education Association, Reston, VA, 2007).  相似文献   
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ABSTRACT

While post-secondary school students with learning difficulties confront many challenges, there is little research on methods of support. In the current study, the ‘adapted course’ model was qualitatively examined from the perspective of both students and instructors. The main goal was to explore how students and instructors perceived the instruction in adapted courses. Five pre-service students with learning disabilities (LD) and/or attention-deficit hyperactivity disorder and three instructors were interviewed. Responses were analysed using subjective analysis, with central content categories identified based on student and instructor statements. Six main themes emerged: (1) small class size; (2) emotional support; (3) adjusted teaching methods; (4) independent practice exercises; (5) instruction by modelling; and (6) instructor characteristics. The current study can inform pedagogical principles on which a support model for post-secondary students with LD can be based. It provides analyses of the effectiveness of one support model and presents the perceptions of both faculty and students. Moreover, the study provides an opportunity to learn about potential components of effective teaching-learning, not only in the specific context of adapted courses, but in any supportive learning situation (e.g. tutoring) or course.  相似文献   
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The study presents a new pedagogical idea and practice for educational practitioners. The practice was developed as a workshop of MA program in order to change and expand the meaning of education for the wellbeing of the community. The ‘place-based learning’ workshop combined action learning (AL) with project-based learning (PBL). The students’ assignment was to develop and operate a plan for the contribution of specific places (e.g. parks, public buildings, organizations and industries) to the community. The findings indicate conceptual and behavioral changes among the students concerning educational processes. At the end of the workshop, the students tended to be more tolerant of ambiguity, sustain judgment and collaborate with peers. The new practice emphasizes coping with fundamental emotional needs such as autonomy, self-efficacy, engagement and belonging. The synergy between AL and PBL was found to have great potential for meaningful learning and doing.  相似文献   
68.
Orbach Y  Lamb ME 《Child development》2007,78(4):1100-1120
Developmental differences in references to temporal attributes of allegedly experienced events were examined in 250 forensic interviews of 4- to 10-year-old alleged victims of sexual abuse. Children's ages, the specific temporal attributes referenced, and the types of memory tapped by the interviewers' questions significantly affected the quantity and quality of temporal references produced. The findings documented age-related increases in 4- to 10-year-olds' references to temporal attributes, using the appropriate relational terminology, both spontaneously and in response to temporal requests. More references to temporal attributes were elicited from recall than from recognition memory, highlighting spontaneous reporting capabilities. Implications for theories concerning the developing understanding of temporal concepts and for the design of effective, age-appropriate, forensic interview techniques are discussed.  相似文献   
69.

Wi-Fi radiation is a type of radio frequency electromagnetic radiation (RF-EMR) that refers to the transfer of energy by radio waves. Nowadays, exposure to RF radiation is widespread including wireless internet connection (Wi-Fi) routers and cell phones. The proliferation of devices emitting RF radiation has entailed some public and media-generated controversy, although scientific evidence has not pointed to the existence of risk. Using the theoretical perspectives of science literacy, public engagement with science, and science media literacy, this work examines public engagement with science-related media reports in a context involving risk. A qualitative design was followed to address multiple viewpoints including an analysis of an authentic primetime TV program concerning the risks of Wi-Fi, its messages, and frames, solicited a public response to the coverage via interviews and decision-making simulation (n = 20), and unsolicited public response based on social media discussions (n = 315 comments). Our findings suggest that a lack of relevant scientific knowledge does not seem to be related to participants’ general scientific literacy among people with higher education. Moreover, interviewees did not place much emphasis on having adequate knowledge in making their decision. These findings emphasize that we need to expand our understanding of the different ways that make scientific knowledge relevant when making decisions on scientific issues that relate directly to everyday life.

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70.
The purpose of this study is to provide insight into short-term professionalization of teachers regarding teaching socioscientific issues (SSI). The study aimed to capture the development of science teachers' pedagogical content knowledge (PCK) for SSI teaching by enacting specially designed SSI curriculum materials. The study also explores indicators of stronger and weaker development of PCK for SSI teaching. Thirty teachers from four countries (Cyprus, Israel, Norway, and Spain) used one module (30–60 min lesson) of SSI materials. The data were collected through: (a) lesson preparation form (PCK-before), (b) lesson reflection form (PCK-after), (c) lesson observation table (PCK-in-action). The data analysis was based on the PCK model of Magnusson, Krajcik, and Borko (1999). Strong development of PCK for SSI teaching includes “Strong interconnections between the PCK components,” “Understanding of students' difficulties in SSI learning,” “Suggesting appropriate instructional strategies,” and “Focusing equally on science content and SSI skills.” Our findings point to the importance of these aspects of PCK development for SSI teaching. We argue that when professional development programs and curriculum materials focus on developing these aspects, they will contribute to strong PCK development for SSI teaching. The findings regarding the development in the components of PCK for SSI provide compelling evidence that science teachers can develop aspects of their PCK for SSI with the use of a single module. Most of the teachers developed their knowledge about students' understanding of science and instructional strategies. The recognition of student difficulties made the teacher consider specific teaching strategies which are in line with the learning objectives. There is an evident link between the development of PCK in instructional strategies and students' understanding of science for SSI teaching.  相似文献   
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