Maintaining the reversibility of foldings: Making the ethics (politics) of information technology visible

This paper will address the question of the morality of technology. I believe this is an important question for our contemporary society in which technology, especially information technology, is increasingly becoming the default mode of social ordering. I want to suggest that the conventional manner of conceptualising the morality of technology is inadequate – even dangerous. The conventional view of technology is that technology represents technical means to achieve social ends. Thus, the moral problem of technology, from this perspective, is the way in which the given technical means are applied to particular (good or bad) social ends. In opposition to this I want to suggest that the assumed separation, of this approach, between technical means and social ends are inappropriate. It only serves to hide the most important political and ethical dimensions of technology. I want to suggest that the morality of technology is much more embedded and implicit than such a view would suggest. In order to critique this approach I will draw on phenomenology and the more recent work of Bruno Latour. With these intellectual resources in mind I will propose disclosive ethics as a way to make the morality of technology visible. I will give a brief account of this approach and show how it might guide our␣understanding of the ethics and politics of technology by considering two examples of contemporary information technology: search engines and plagiarism detection systems.     

ERP实施与企业竞争优势分析

依据资源理论竞争优势模型,探讨了ERP的价值性、稀缺性、模仿性和组织性。认为ERP系统能给企业带来暂时竞争优势,但ERP实施及操作技能带来的竞争优势则是持续长久的。     

Serum adenosine deaminase, 5′ nucleotidase and malondialdehyde in acute infective hepatitis

Serum adenosine deaminase (ADA), 5′ nucleotidase (5′NT) and malondialdehyde (MDA) were estimated in patients with acute infective hepatitis (AIH) along with the routine parameters of liver disease. Present study is done to evaluate these special parameters in patients with clinical history of AIH and to assess the utility of these parameters as diagnostic/ prognostic indices of liver function and to correlate special parameters with routine live function tests (LFT). ADA, 5′NT and MDA along with routine LFT was estimated in 25 patients with AIH and 25 samples from healthy voluntary blood donars served as the control group. Routine LFT was estimated by standard clinical chemistry procedures on dade behring analyser and ADA, 5′NT and MDA were estimated by berthlot reaction, fiske and subbarao method and thiobarbituric acid method respectively. Statistical analysis showed that serum ADA, 5′NT and MDA were significantly higher in patients as compared with the controls. There was a significant positive correlation between ADA and total bilirubin and MDA and total bilirubin. Hence we can conclude that these tests would be more sensitive to diagnose the patients with AIH and that the raised bilirubin levels could be looked upon, as a protective mechanism which the liver has evolved in order to combat oxidative stress.     

基于文本挖掘和技术路线图的技术创新机会发现

本文在介绍文本挖掘和技术路线图研究情况的基础上，探讨如何将文本挖掘和技术路线图结合起来，通过挖掘隐含在科技信息中的知识和联系，并结合技术领域专家，绘制技术路线图，以帮助技术主管发现技术创新的机会。     

两类典型产业生态系统的建模及比较研究

基于两类典型的产业生态系统建立基本数学模型,提出清洁生产系数和耦合适应度系数概念,在运用数学模型对生态产业园区的几种类型进行解释说明的基础上,得出清洁生产具有广泛的适用性,生态产业园区和区域副产品循环网络具有相对的适用性,而技术创新是产业生态系统成功运行的关键因素等结论。     

工艺创新机制研究:来自中国汽车企业的实证

现有产品创新研究文献远远多于工艺创新文献,而对于工艺创新机制的研究更为少见。本文结合文献调研、专家访谈和汽车企业工艺实践,构建了汽车企业工艺创新机制理论模型和研究假设,利用结构方程模型对假设进行了检验。研究发现,决策机制对动力机制、组织机制和激励机制有正向作用,但决策机制对企业工艺创新能力没有直接影响;动力机制、组织机制直接影响工艺创新能力,动力机制的作用相对较弱;组织机制对激励机制的正向作用和激励机制对工艺创新能力的正向作用都没有通过检验。本文对丰富工艺创新研究具有重要的学术价值,研究成果有利于促进企业和政府加强对工艺创新重视。     

Induction of diabetes by Streptozotocin in rats

The objective of this study is to induce experimental diabetes mellitus by Streptozotocin in normal adult Wistar rats via comparison of changes in body weight, consumption of food and water, volume of urine and levels of glucose, insulin and C-peptide in serum, between normal and diabetic rats. Intra-venous injection of 60mg/kg dose of Streptozotocin in adult wistar rats, makes pancreas swell and at last causes degeneration in Langerhans islet beta cells and induces experimental diabetes mellitus in the 2–4 days. Induction of experimental diabetes mellitus is indeed the first step in the plan of purification of pancreatic Langerhans islet cells of normal rats for transplanting under the testis subcutaneous of experimentally induced diabetic rats. Streptozotocin induces one type of diabetes which is similar to diabetes mellitus with non-ketosis hyperglycemia in some animal species. For induction of experimental diabetes in male adult rats weighted 250–300 grams (75–90 days), 60mg/kg of Streptozotocin was injected intravenously. Three days after degeneration of beta cells, diabetes was induced in all animals. The diabetic and normal animals were kept in the metabolic cages separately and their body weight, consumption of food and water, urine volume, the levels of serum glucose, insulin and C-peptide quantities in all animals were measured and then these quantities were compared. For a microscopic study of degeneration of Langerhans islet beta cells of diabetic rats, sampling from pancreas tissue of diabetic and normal rats, staining and comparison between them, were done. Induction of diabetes with Streptozotocin decreases Nicotinamide-adenine dinucleotide (NAD) in pancreas islet beta cells and causes histopathological effects in beta cells which probably intermediates induction of diabetes. In this study, we used Streptozotocin for our experiments in induction of experimental diabetes mellitus. After Induction of diabetes, consumption of food and water, volume of urine and glucose increased in the diabetic animals in comparison with normal animals, but the weight of body and the volume of insulin and C-peptide decreased in the diabetic animals. Sampling and staining of pancreas tissue of diabetic and normal rats showed that the Langerhans islet beta cells of diabetic rats have been clearly degenerated. In three days, Streptozotocin makes pancreas swell and at last causes degeneration in Langerhans islet beta cells and induces experimental diabetes. It also changes normal metabolism in diabetic rats in comparison with normal rats. Consumption of water and food, volume of urine, serum glucose increases in diabetic animals in comparison with normal rats but the levels of serum insulin, C-peptide and body weight decreases.     

一种有效缓解数据稀疏问题的协同过滤推荐算法

传统协同过滤推荐算法依据共同评分项目计算用户相似度, 进而产生推荐项目。然而, 随着用户和商品数量的不断增加, 用户共同评分的项目会越来越少, 甚至没有, 因此传统协同过滤推荐算法对用户之间相似度的衡量将会越来越不准确, 从而影响推荐系统的性能。针对这一问题, 本文对用户相似度的计算方法进行了改进, 提出直接相似度和间接相似度的概念, 同时引入关键人物权重, 进一步提高推荐系统的准确性。