Non-targeted metabolomics in sport and exercise science

Metabolomics incorporates the study of metabolites that are produced and released through physiological processes at both the systemic and cellular levels. Biological compounds at the metabolite level are of paramount interest in the sport and exercise sciences, although research in this field has rarely been referred to with the global ‘omics terminology. Commonly studied metabolites in exercise science are notably within cellular pathways for adenosine triphosphate production such as glycolysis (e.g., pyruvate and lactate), β-oxidation of free fatty acids (e.g., palmitate) and ketone bodies (e.g., β-hydroxybutyrate). Non-targeted metabolomic technologies are able to simultaneously analyse the large numbers of metabolites present in human biological samples such as plasma, urine and saliva. These analytical technologies predominately employ nuclear magnetic resonance spectroscopy and chromatography coupled to mass spectrometry. Performing experiments based on non-targeted methods allows for systemic metabolite changes to be analysed and compared to a particular physiological state (e.g., pre-/post-exercise) and provides an opportunity to prospect for metabolite signatures that offer beneficial information for translation into an exercise science context, for both elite performance and public health monitoring. This narrative review provides an introduction to non-targeted metabolomic technologies and discusses current and potential applications in sport and exercise science.     

The knowledge society and the internationalization of Japanese higher education

The internationalization of higher education is considered to be a major policy agenda in the global knowledge society. For Japan, internationalization has been a key driver in academic and social advancement, while its traditional culture and national identity have also been retained. Recently, a series of policies have been presented by the government, university, and industry to attract more students and top calibre researchers from Asia and further afield, and to enhance exchange and collaboration, internationalization at home, and global human resource development. Concurrently, the controversial nature of internationalization has been pointed out, as well as the stagnant mobility of Japanese students and their inward-looking attitude. This paper discusses the internationalization of Japanese higher education by examining the relevant policy, practice, and perceptions of the people and institutions concerned. The major findings reveal the complexity of internationalization as a dynamic process of change, its vulnerability and marginality, and the extent of the gap between policy and practice. The author also addresses the increased relevance of the research in this field to policy-making and practice in education and its contribution to the production of new knowledge.     

Childhood maltreatment and conduct disorder: Independent predictors of criminal outcomes in ADHD youth

ObjectiveChildren with attention-deficit/hyperactivity disorder (ADHD) are at heightened risk for maltreatment in childhood and criminality as they enter into adolescence and early adulthood. Here, we investigated the effect of moderate to severe childhood maltreatment on later criminality among adolescents/young adults diagnosed with ADHD in childhood while accounting for the contributions of other known risk factors such as early conduct disorder (CD).MethodsEighty-eight participants from a longitudinal study of children diagnosed with ADHD and screened for comorbid disorders at age 7–11 years were assessed for maltreatment histories at the time of the 10-year adolescent follow-up. Detailed juvenile and adult criminal records were obtained from the New York State Division of Criminal Justice Services approximately 3-years after commencement of the follow-up study. We used regression analyses to determine predictors of adolescent/young adult criminal behavior.ResultsModerate to severe childhood maltreatment increased the risk of adolescent/young adult arrest over and above the risk associated with childhood CD, while both childhood maltreatment and childhood CD significantly increased the risk of recidivism. ADHD youth classified as maltreated were three and a half times more likely to be arrested when compared to ADHD youth without a maltreatment classification.ConclusionWe established maltreatment as a risk factor for criminality in ADHD youth and demonstrated that this relationship was independent of the contributions of CD, and established risk factor for antisocial behavior in this population. The findings highlight the need for maltreatment screening in children with ADHD in order to identify those at heightened risk for criminal activity, and target treatment to improve outcome in this high-risk group of children.     

Parental Participation and Accountability in Primary Schools in Uganda

Participation, a 'buzzword' in social development in both developed and developing countries, has several different interpretations in terms of purpose, form and implication. For instance, parents are encouraged to participate individually in choosing the school for their own children, and they are expected to participate collectively in school development through the work of school governing bodies. Furthermore, participation in education is often considered to be a means of assuring accountability of decentralised institutions. This paper explores the notion of parental participation in school governance, based on data obtained from field research in Uganda. It argues that parents' perceptions of the accountability of the school affect the way they participate in education. Thus, accountability is one of the crucial factors for realising local democracy through decentralisation.     

Scientific evidence by fluorescence spectrometry for safflower red on ancient Japanese textiles stored in the Shosoin Treasure House repository

Shosoin textiles, handed down from the eighth century in Nara, Japan, have entranced many people with their beautiful colors made from natural dyes. Dye analysis of the Shosoin textiles, including the red carpet laid inside the workshop hall at the Todaiji Temple in Nara, used for the inauguration of the statue of the Great Buddha in the temple in 752 AD; a red undergarment and a gown with a tie-dyed design worn by craftsmen in the Todaiji Temple; and embroidered shoes belonging to Empress Komyo (701–760 AD), were conducted by excitation–emission matrix fluorescence spectrometry equipped with a fiber optics probe. Comparison of the spectra to references identified safflower red (Carthamus tinctorius L.) in the red or orange areas on these original textiles. The spectrometry of the gown and the shoes offered the identification not only of safflower red but also of amur cork tree. This study finds these examples to be the oldest scientifically confirmed presence of safflower red on historic textiles at present.     

Comparative Education in a Microcosm: Methodological Insights from the International Schools Sector in Hong Kong

Many studies in the field of comparative education take national education systems as the basic unit of analysis. The present paper has been conceived within this tradition, but has a different angle of approach. It focuses on 47 international schools in a small territory. Some of the international schools were grouped into larger systems but others were free-standing institutions. The focus of the paper thus lies at an intersection between cross-national and intra-national comparisons. It makes methodological observations on the nature of comparisons that are possible within such a microcosm, and on the conceptual lessons that can be derived from such analysis.