Use of NSE/PS2m-transgenic mice in the study of the protective effect of exercise on Alzheimer's disease

In its late stage, Alzheimer's disease results in progressive muscle weakness in the arms and legs. The aim of this study was to determine whether mice expressing the skeletal muscle-specific mutant PS2 gene (a model of Alzheimer's disease) are a useful experimental system to study the protective effect of exercise on Aβ-42 reduction, improvement of behavioural function and changes in metabolic parameters. With this aim in mind, the transgenic mice were subjected to treadmill exercise for 3 months. The results showed that in transgenic mice, but not in normal mice, treadmill exercise resulted in a reduction of Aβ-42 deposits and an improvement in behavioural function, thereby restoring normal concentrations of total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and triglyceride. Thus, exercise may represent a practical therapeutic strategy for use with human patients with Alzheimer's disease.     

A comparison of the Rescorla-Wagner and Pearce models in a negative patterning and a summation problem

In two experiments, we examined two related conditioning problems previously investigated by Red-head and Pearce (1995a) and Pearce, Aydin, and Redhead (1997). Experiment 1 involved an A+, B+, C+, AB+, AC+, BC+, ABC2 discrimination. The Rescorla-Wagner model predicts that response to AB, AC, and BC will be greater than that to A, B, and C at asymptote, whereas the Pearce model makes the opposite prediction. In Experiment 2, we investigated the responding to a novel ABC compound in groups trained with either A+, B+, C+ or AB+, AC+, BC+. The Rescorla-Wagner model predicts greater response to ABC in the group trained with A+, B+, C+ than in the group trained with AB+, AC+, BC+, whereas the Pearce model makes the opposite prediction. In contrast to the findings of Redhead and Pearce (1995a) and Pearce et al. (1997) in pigeon autoshaping, our findings in rabbit eyelid conditioning support the Rescorla-Wagner model.     

How will net neutrality be played out in Korea?

The network neutrality debate is closely related to social, political, and economic debates over the public information network and the duties of its private carriers. The paper begins by defining network neutrality before discussing the technology underpinning network neutrality. It then contextualizes the issue in terms of policy, innovation, values, and society of Korean context. It compares the different approaches adopted by other countries to the regulation of network neutrality. Regulatory approaches to net neutrality can be either devising a comprehensive regulatory framework or abandoning the option of regulatory intervention altogether. We propose a careful combination of government intervention and market forces as a Korean model for allowing networks to remain a free and open marketplace of ideas and economic, political, and social interactions. The results offer useful references on net neutrality in other countries.     

Correlation analysis-based image segmentation approach for automatic agriculture vehicle

INTRODUCTION In recent years,harvesting crop by combine has become more and more popular in China.In2003,combines were used to harvest23%of rice and71%of wheat.The work described here is part of a pro-ject aimed at researching automatic combines who follow the cut-uncut edge of the crops automatically to reduce the driver’s fatigue from the intensive work.Much attention has been focused on vision-bas-ed automatic agriculture vehicle.Image segmenta-tion is the key to extracting the guida…     

Potential for knowledge in action? An analysis of Korean green energy related K3–12 curriculum and texts

While understanding green energy development and what drives it are important, there is increasing consensus that sustainability transitions concerning usage need to be viewed in terms of the place specific contexts, including education, that critically mold them. In order to support sustainability transitions, information and knowledge building are not enough; knowledge must be turned into action. This research examines the potential efficacy of Korea’s efforts in this regard via an analysis of K3–K12 geography education curriculum and texts vis-à-vis green energy content. There is scant disconnect between the curriculum and the texts analyzed, and, aside from the small shortcomings unearthed, analyses suggest that Korea is cogent of the ability of geography education and education for sustainable development to turn knowledge into action, thereby empowering civil society to drive its green energy transitions going forward.     

Enhancing Student Learning in Food Engineering Using Computational Fluid Dynamics Simulations

Abstract: The current generation of students coming into food science and engineering programs is very visually oriented from their early experiences. To increase their interest in learning, new and visually appealing teaching materials need to be developed. Two diverse groups of students may be identified based on their math skills. Food science students tend to find it difficult to use mathematics as a problem‐solving tool for food engineering problems. Food engineering students, on the other hand, should be challenged to use emerging mathematical tools to develop their problem‐solving skills. Therefore, the approach of this project involved the development of a curriculum to train undergraduate food engineers in the effective use of computational fluid dynamics (CFD) software to solve food engineering problems by engaging them in the creation of food engineering teaching tools. These CFD outputs were then used as innovative teaching tools for the food science students. In this paper, this concept will be illustrated by unsteady‐state heat transfer and fluid flow problems. To evaluate the efficiency of the teaching materials developed, a student focus group was asked to answer the same quiz following a conventional and CFD output aided teaching session. The assessment result showed an improved understanding of the subject after the CFD teaching session. These visual aids were excellent tools to illustrate the validity of the formulas presented in class. In addition, the new visual materials enabled a better understanding of the relationships among different process parameters. In general, this helped the food science students better appreciate the food engineering concepts that govern food processing operations.     

Improving Environmental Conditions in the Tomb of Tutankhamen

ABSTRACT

The tomb of Tutankhamen in the Valley of the Kings, Egypt, one of the major attractions of the World Heritage Site of Ancient Thebes and its Necropolis on the West Bank of modern day Luxor, is today a destination for mass tourism. Visitors to the tomb increase relative humidity, elevate carbon dioxide levels, and encourage natural ventilation which facilitates entry of dust into the tomb. These conditions negatively impact the wall paintings and remaining artifacts in the tomb and create an uncomfortable environment for visitors. The deposition of dust inside the tomb collects on uneven wall painting surfaces, obscures their legibility and necessitates cycles of cleaning, which in turn leads to further damage. Developing environmental management strategies in the tomb to counter the effects of visitors and mitigate dust entry is an important component of the collaborative project between the Getty Conservation Institute (GCI) and Egypt’s Ministry of Antiquities (MoA) to conserve the tomb. These included implementation of a filtered-air supply and exhaust ventilation system to stabilize the interior microclimate and reduce dust in order to improve visitor comfort and contribute to the long-term preservation of the tomb.     

The role of negative emotions on motivation and communicative action: Testing the validity of situational theory of problem solving in the context of South Korea

The purposes of this study are to explore the role of negative emotions in the framework of the situational theory of problem solving (STOPS). First, we tested the validity of the original STOPS model with a sex crime issue in the context of Korea. Second, we tested the mediating role of negative emotions in the relationship between situational recognition and communicative action. The result suggests that STOPS is a useful model with a crime problem in the Korean context. Also, our proposed model shows that negative emotions serve as another aspect of motivation, and emotional experiences might precede subsequent cognitive activities. Especially, negative emotions show a stronger effect on situational motivation than communicative action. This study also found that negative emotions people feel about sex crimes directly influence their communicative action. Among different types of publics, the active and aware publics show stronger emotional responses than do the latent publics and nonpublics.