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Two experiments were conducted to examine whether and how 4- and 5-year-olds learn to distinguish determinate from indeterminate evidence. Children were asked to decide whether various patterns of evidence were sufficient to reach unambiguous conclusions. This study replicated the finding that young children tend to use a strategy that, although generally successful, fails on evidence patterns in which a single positive instance co-occurs with an unexplored source of evidence. Experiment 1 demonstrated that this positive-capture strategy is deeply entrenched, even in a meaningful, pragmatic context. With a microgenetic design, Experiment 2 revealed that young children are capable of replacing the positive-capture strategy with a correct strategy when they are exposed to various analogous tasks in several training sessions. 相似文献
134.
In their recent study, Udell, Dorey, and Wynne (in press)[COMP: Ref. is LBE0034. Will have to be updated to (2011) here and in LBE0038, once page nos. are available.] showed that
in a begging task, at least in some conditions, dogs as well as wolves preferentially approached a human partner who could
see them in contrast to one whose eyes were occluded, and Udell et al. concluded that this success was dependent on the subjects’
experiences with the specific occluder used. Here we argue, however, that since both partners expressed similar attentiveness
towards the subjects by calling their names, Udell and colleagues’ conclusion does not refer to the sensitivity of canines
to others’ attentiveness, but instead reflects the fact that the animals obeyed a familiar command better in a familiar context
than in an unfamiliar one. Moreover, in contrast to Udell et al.’s conclusion, we believe that their data demonstrate that
pet dogs can generalize the use of the visibility of human eyes to novel situations, showing a preference towards an attentive
partner even if the eyes of the other partner are occluded in a novel way (e.g., having a bucket on his or her head). Finally,
after presenting alternative interpretations of the results of the wolves tested by Udell and colleagues, we conclude that
there is no evidence that wolves are sensitive to the attentional states of humans. 相似文献
135.
Seeking potential toxic and side effects for clinically available drugs is considerably beneficial in pharmaceutical safety evaluation. In this article, the authors developed an integrated microfluidic array system for phenotype-based evaluation of toxic and teratogenic potentials of clinical drugs by using zebrafish (Danio rerio) embryos as organism models. The microfluidic chip consists of a concentration gradient generator from upstream and an array of open embryonic culture structures by offering continuous stimulation in gradients and providing guiding, cultivation and exposure to the embryos, respectively. The open culture reservoirs are amenable to long-term embryonic culturing. Gradient test substances were delivered in a continuous or a developmental stage-specific manner, to induce embryos to generate dynamic developmental toxicity and teratogenicity. Developmental toxicity of doxorubicin on zebrafish eggs were quantitatively assessed via heart rate, and teratological effects were characterized by pericardial impairment, tail fin, notochord, and SV-BA distance ∕body length. By scoring the teratogenic severity, we precisely evaluated the time- and dose-dependent damage on the chemical-exposed embryos. The simple and easily operated method presented herein demonstrates that zebrafish embryo-based pharmaceutic assessment could be performed using microfluidic systems and holds a great potential in high-throughput screening for new compounds at single animal resolution. 相似文献
136.
Definitions of bullying: a comparison of terms used,and age and gender differences,in a fourteen-country international comparison 总被引:2,自引:0,他引:2
Smith PK Cowie H Olafsson RF Liefooghe AP Almeida A Araki H del Barrio C Costabile A Dekleva B Houndoumadi A Kim K Olafsson RP Ortega R Pain J Pateraki L Schafer M Singer M Smorti A Toda Y Tomasson H Wenxin Z 《Child development》2002,73(4):1119-1133
The study of school bullying has recently assumed an international dimension, but is faced with difficulties in finding terms in different languages to correspond to the English word bullying. To investigate the meanings given to various terms, a set of 25 stick-figure cartoons was devised, covering a range of social situations between peers. These cartoons were shown to samples of 8- and 14-year-old pupils (N = 1,245; n = 604 at 8 years, n = 641 at 14 years) in schools in 14 different countries, who judged whether various native terms cognate to bullying, applied to them. Terms from 10 Indo-European languages and three Asian languages were sampled. Multidimensional scaling showed that 8-year-olds primarily discriminated nonaggressive and aggressive cartoon situations; however, 14-year-olds discriminated fighting from physical bullying, and also discriminated verbal bullying and social exclusion. Gender differences were less appreciable than age differences. Based on the 14-year-old data, profiles of 67 words were then constructed across the five major cartoon clusters. The main types of terms used fell into six groups: bullying (of all kinds), verbal plus physical bullying, solely verbal bullying, social exclusion, solely physical aggression, and mainly physical aggression. The findings are discussed in relation to developmental trends in how children understand bullying, the inferences that can be made from cross-national studies, and the design of such studies. 相似文献
137.
A simple method of irreversibly sealing SU-8 microfluidic channels using PDMS is reported in this paper. The method is based on inducing a chemical reaction between PDMS and SU-8 by first generating amino groups on PDMS surface using N2 plasma treatment, then allowing the amino groups to react with the residual epoxy groups on SU-8 surface at an elevated temperature. The N2 plasma treatment of PDMS can be conducted using an ordinary plasma chamber and high purity N2, while the residual epoxy groups on SU-8 surface can be preserved by post-exposure baking SU-8 at a temperature no higher than 95 °C. The resultant chemical bonding between PDMS and SU-8 using the method create an interface that can withstand a stress that is greater than the bulk strength of PDMS. The bond is permanent and is long-term resistant to water. The method was applied in fabricating SU-8 microfluidi-photonic integrated devices, and the obtained devices were tested to show desirable performance. 相似文献
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139.
在圣托里尼岛与一位摄影师结为好友。聊天中,他说他偶尔会为一些新婚夫妻拍婚纱照,在拍摄过程中他发现一个很有趣的现象。“每个人都想拍蓝天、大海、教堂的十字尖顶,以及号称世界上最美的日落。我对他们说,再走下去一点,会有很漂亮的巷子和小花,但很少有人愿意去拍。”“为什么?” 相似文献
140.