20世纪下半叶西方高等教育民主化和职业化特征分析

二战后西方高等教育领域发生了根本性的变化,与战前相比较高等教育民主化和职业化特征突出。战后西方世界出现的社会民主化运动推进了高等教育民主化,高等教育规模和入学机会均等都得到了相应的发展和提高;入学人数的增加以及社会经济的发展需求,高等教育职业化倾向明显,主要表现在高等职业教育的快速发展和普通高等教育专业和课程的职业化倾向。     

一种应用于电容式微机械陀螺的改进型积分器研究

电容式微机械陀螺通常都采用积分器作为前级输入模块,实现高频调制和电容电压转换的功能.传统积分器的转换增益与反馈电容成反比,而反馈电容的值太小,会引起电路自激震荡,因此传统积分器对有用信号的放大倍数有限,系统的信噪比较低.对此,提出了一种应用于电容式微机械陀螺的改进型积分器,这种积分器的转换增益可以通过调节电容比值而得到较大值,因此能够提高系统的信噪比.该文在分别分析两种积分器工作原理的基础上,通过理论分析及仿真结果对比,证明了改进型积分器能够提高有用信号的放大倍数.     

试论高职院校提升学生就业能力的若干举措

近几年随着高考的扩招,大学毕业生基数逐年递增,就业形势越来越严峻,大学生的就业情况已经受到了各级政府相关部门和各高校的高度重视。导致就业难有多方面的因素,高职院校学生相对其他类别的大学生就业率偏低,最主要的原因在于大学生就业能力的欠缺,所以本文根据工作实际经验,就高职院校如何提升学生就业能力进行了探讨。     

论我国小额消费纠纷的解决机制

在我国小额消费纠纷已成为一种大量发生的诉讼现象,应当根据此类纠纷的特点,借鉴国外的有益经验,建立行之有效的小额消费者纠纷解决机制,包括给予和解或调解协议必要的法律约束力;赋予行政执法机关行政裁决权;建立专门的消费争议仲裁制度;设立小额诉讼法庭;完善代表人诉讼制度等。     

统筹城乡发展理念下城乡居民公正发展思考

统筹城乡发展不仅是要统筹实现城乡经济社会的协调发展,而且要统筹实现城乡居民的公正发展。城乡居民公正发展就是要实现城乡居民发展的权利公平,发展的机会公平,发展的规则公平,发展的成果分配公平。     

咖啡因对6-羟基多巴胺诱导大鼠帕金森病模型作用的量效关系

目的：探讨咖啡因对大鼠6－羟基多巴胺（6-OHDA）诱导的帕金森模型作用的量效关系及其最佳用量。方法：应用6-OHDA制备成年大鼠右侧损毁的帕金森病模型,通过外周注射阿朴吗啡促使大鼠旋转次数作为对其病情进行定量检测的指标。用已知不同剂量的咖啡因每天对大鼠灌胃进行治疗,以大鼠旋转次数为主要指标,判断其对帕金森病治疗效果的变迁情况,以探讨咖啡因治疗帕金森病的最佳剂量。结果：咖啡因（30,40,50mg／kgBW）有明显治疗效果,但咖啡因40,50mg／kgBW组对大鼠有可能产生生存质量影响。结论：30mg／kgBW是咖啡因治疗6-OHDA制备帕金森大鼠模型的有效剂量,咖啡因对帕金森病的疗效随剂量增长,到一定剂量时则不再增长。     

梅毒血清学检测方法进展及评价

梅毒螺旋体血清学试验是目前国内外诊断梅毒最主要的实验室检查方法.了解并掌握梅毒血清学检测方法对梅毒的早期发现和控制有重大意义.本文就近年来血清学实验中非梅毒螺旋体抗原血清试验和梅毒螺旋体抗原血清试验两方面进行综述.     

Development of a large-scale isolation chamber system for the safe and humane care of medium-sized laboratory animals harboring infectious diseases

The close phylogenetic relationship between humans and non-human primates makes non-human primates an irreplaceable model for the study of human infectious diseases. In this study, we describe the development of a large-scale automatic multi-functional isolation chamber for use with medium-sized laboratory animals carrying infectious diseases. The isolation chamber, including the transfer chain, disinfection chain, negative air pressure isolation system, animal welfare system, and the automated system, is designed to meet all biological safety standards. To create an internal chamber environment that is completely isolated from the exterior, variable frequency drive blowers are used in the air-intake and air-exhaust system, precisely controlling the filtered air flow and providing an air-barrier protection. A double door transfer port is used to transfer material between the interior of the isolation chamber and the outside. A peracetic acid sterilizer and its associated pipeline allow for complete disinfection of the isolation chamber. All of the isolation chamber parameters can be automatically controlled by a programmable computerized menu, allowing for work with different animals in different-sized cages depending on the research project. The large-scale multi-functional isolation chamber provides a useful and safe system for working with infectious medium-sized laboratory animals in high-level bio-safety laboratories.     

Comparative features of colorectal and gastric cancers with microsatellite instability in Chinese patients

Objective  

The purpose of this study was to determine the unique and universal features of microsatellite instability-high (MSI-H) colorectal cancer (CRC) and MSI-H gastric cancer (GC) in the Chinese population.     

Preparation of high-affinity rabbit monoclonal antibodies for ciprofloxacin and development of an indirect competitive ELISA for residues in milk

A convenient competitive enzyme-linked immunosorbent assay (ELISA) for ciprofloxacin (CPFX) was developed by using rabbit monoclonal antibodies (RabMAbs) against a hapten-protein conjugate of CPFX-bovine serum albumin (BSA). The indirect competitive ELISA of CPFX had a concentration at 50% inhibition (IC₅₀) of 1.47 ng/ml and a limit of detection (LOD) of 0.095 ng/ml. The mAb exhibited some cross-reactivity, however, not so high with enrofloxacin (28.8%), ofloxacin (13.1%), norfloxacin (11.0%), fleroxacin (22.6%), and pefloxacin (20.4%). And it showed almost no cross-reactivity with other antibiotics or sulfonamides evaluated in this study. The competitive ELISA kit developed here could be used as a screening tool to detect and control illegal addition of CPFX in food products. This kit had been applied to milk detection and the recovery rates from samples spiked by CPFX were in a range of 63.02%–84.60%, with coefficients of variation of less than 12.2%.