静态各向异性荷电流体内部引力场

本文得到了质量密度和电荷密度都随半径变化的静态球对称各向异性荷电流体的E—M方程的一组严格解,当参数取一些特定值时,本解可退化为多个已知的严格解。     

中学生物学教学应贯穿正确的思想观点

在中学生物学教学中经常能够听到类似“鸟为了飞翔而长有翅膀”的说法,“鸟”真的能够“为了飞翔而长有翅膀”吗?答案是否定的。在教学中,这是一种思想性错误,那么,为什么会出现思想性错误?1生物学教学中的思想性错误及其根本原因教学的思想性是指在教学中要用正确的观点阐述教     

贾平凹小说的女性形象创作理念

贾平凹作品中塑造了许多女性形象，体现了他对女性的体悟、思考和关注，同时形成了他对现代女性应然状态的成熟看法．做女人既要自我本色又要虚饰脸面。     

Kinesin KIF4A is associated with chemotherapeutic drug resistance by regulating intracellular trafficking of lung resistance-related protein

Multidrug resistance (MDR) is the major impediment to cancer chemotherapy. The expression of lung resistance-related protein (LRP), a non-ATP-binding cassette (ABC) transporter, is high in tumor cells, resulting in their resistance to a variety of cytotoxic drugs. However, the function of LRP in tumor drug resistance is not yet explicit. Our previous studies had shown that Kinesin KIF4A was overexpressed in cisplatin (DDP)-resistant human lung adenocarcinoma cells (A549/DDP cells) compared with A549 cells. The expression of KIF4A in A549 or A549/DDP cells significantly affects cisplatin resistance but the detailed mechanisms remain unclear. Here, we performed co-immunoprecipitation experiments to show that the tail domain of KIF4A interacted with the N-terminal of LRP. Immunofluorescence images showed that both the ability of binding to LRP and the motility of KIF4A were essential for the dispersed cytoplasm distribution of LRP. Altogether, our results shed light on a potential mechanism in that motor protein KIF4A promotes drug resistance of lung adenocarcinoma cells through transporting LRP-based vaults along microtubules towards the cell membrane. Thus KIF4A might be a cisplatin resistance-associated protein and serves as a potential target for chemotherapeutic drug resistance in lung cancer.     

浅谈一元微积分学在证不等式中的应用

从一元微积分知识应用的角度,给出证不等式的八种方法:极值法、最值法、泰勒公式法、凹凸性法、被积函数放缩法、柯西积分不等式法、辅助函数积分法、上凹函数积分法。     

PEMFC分散发电系统的压力控制研究

NomenclatureA-area ( m2)Dw-membrane water diffusivity ( m2/s)F-=96 487I-current (A)M-molecule mass (kg/mol)T-temperature (K)W-mass flowrate (kg/s)cw-water concentration in membrane ( mol/m3)m-mass (kg)n-cell numbernd-electro-osmotic drag coefficientp-pres…     

对中职教师在职攻读硕士学位培养方案的思考

文章阐述了中职教师的特点和任务,分析了中职教师在职攻读硕士学位培养过程中的学习内容,探讨了中职教师在职攻读硕士学位培养方案的制订原则,并以模块化方式对中职教师在职攻读硕士学位的培养方案进行了设计.     

长江下游三省—市农业自然资源利用方向和发展对策

沪、苏、浙、皖三省一市,处于长江下游平原水网地区。并有丘陵、低山分布,属暖温带和北、中亚热带气候区,濒临黄海、东海,每年为国家提供大量农产品。要利用上海浦东开发、沿海、沿江城市开放的有利条件,通过改造中低产田,利用零星荒地,开发滩涂、水面,以高产、优质、高效农业为目标,加速发展优质稻、小麦、蚕丝、棉花、瘦肉型猪、水禽、海水鱼、对虾、茶叶、特种水果等农产品,满足国内人民需要,并增加外汇收入。     

城市化和农村人口犯罪现况浅析

在我国城市化加速发展的进程中,农村人口犯罪随之增多。城乡经济上的差距、文化背景以及农村基层管理均是引发农村人口犯罪的因素。预防和治理农村人口犯罪的根本在于切实解决好“三农”问题。     

论职务发明创造的非职务化流失

职务发明创造非职务化，是单位甚至国有专利权流失的一条重要途径。本比较系统地探讨了职务发明创造非职务化的表现形式，分析了导致职务发明创造非职务化的原因，最后提出了遏制职务发明创造非职务化的对策。