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Shailja Chambial Kamla Kant Shukla Shailendra Dwivedi Pankaj Bhardwaj Praveen Sharma 《Indian journal of clinical biochemistry : IJCB》2015,30(3):357-359
Lead interferes with a variety of body processes and is toxic to many organs and tissues including the heart, bones, intestines, kidneys, and reproductive and nervous systems. Routes of exposure to lead include contaminated air, water, soil, food, and consumer products. The possibility of lead exposure in humans is therefore of great significance from health point of view. Occupational exposure is a common known cause of lead poisoning in adults but current status of adults exposed otherwise is not known. School teachers representing wide local population were selected and asked to furnish information regarding possible lead exposure. Blood lead level (BLL) was estimated using anodic stripping voltammetry. The mean BLL was 6.89 ± 9.5 μg/dl (<3.5–>65 μg/dl) in representative adult population. Out of the total 16 % were found to be having BLL >10 μg/dl which has significantly decreased from leaded gasoline era. Those with increased BLL (>10 μg/dl) were found to have common determinants like usage of old metallic pipes for plumbing, water consumption without any purification system, usage of cosmetics and Ayurvedic/herbal medicines. 相似文献
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Arun Kumar Singh Sunita Tiwari Abhishek Gupta Kamla Kant Shukla Kumar Gaurav Chhabra Achileshwar Pandey Aditya Bhushan Pant 《Indian journal of clinical biochemistry : IJCB》2015,30(3):255-262
Metabolic syndrome (MetS) is a cluster of interrelated common clinical disorders. The role of resistin in insulin sensitivity and MetS is controversial till date. So, the aim of the present study was to investigate the relationship of plasma resistin levels with markers of the MetS in Indian subjects. In a case control study, total 528 subjects were selected for the study. 265 (194 male and 71 female) were cases (with MetS) and 263 (164 male and 99 female) were controls (without MetS). Required anthropometric measurements and calculations were carried out accordingly. All the Biochemical estimations were carried out according to standard protocol. Resistin level was measured by the standard protocol (By ELISA i.e. enzyme linked immunosorbent assay) as illustrated in the kit. Insulin level was also measured by the standard protocol as illustrated in the kit and insulin resistance was calculated by the standard procedures. Plasma resistin levels were significantly higher in cases compared with controls (male = 13.05 ± 4.31 vs. 7.04 ± 2.09 ng/ml; p ≤ 0.001 and female = 13.53 ± 4.14 vs. 7.42 ± 2.30 ng/ml; p ≤ 0.001). Plasma resistin levels were well correlated with waist circumference, glucose, triglycerides, waist/hip ratio, systolic and diastolic blood pressure, high density lipoprotein, total cholesterol, serum low density lipoprotein, serum very low density lipoprotein, insulin and insulin resistance. Plasma resistin levels were elevated in presence of the MetS and were associated with increased metabolic risk factors. 相似文献
304.
Comparing the fit of alternative models has become a standard procedure for analyzing covariance structure analysis. Comparison of alternative models is typically accomplished by examining the fit of each model to sample data. It is argued that rather than using this indirect approach, one should do direct comparisons of the similarities and differences among competing models. It is shown that among the existing good‐ness‐of‐fit indexes, the root mean square residual (RMSR) is the only one that can be used for this purpose. However, the RMSR fails to satisfy some important statistical desiderata. Rao's Distance (RD), an alternate measure, is shown to overcome this limitation of RMSR. The preference for RD over RMSR for model comparisons is illustrated through a detailed analysis of a particular sample of multitrait‐multimethod data. A simulation study conducted to empirically investigate the sampling behavior of RD reveals that the true orderings of intermodel proximities are recovered (on average) with a fair degree of accuracy. 相似文献
305.
本文以维多利亚州为例,概括、分析了澳大利亚融合教育的法律、政策框架和发展趋势,分析了维多利亚州以“教和学”为核心的服务体系、“一体化”的融合教育服务模式和跨学科的专业服务模式,讨论了融合教育发展与普通教育体系变革之间的深刻联系. 相似文献
306.
P. Bubber A. Sharma A. Chauhan D. D. Bansal 《Indian journal of clinical biochemistry : IJCB》2013,28(2):193-196
Growth retardation is one of the significant changes in chronic kidney disease (CKD) and is associated with increased morbidity and mortality. Disturbances in growth hormone (GH) are held responsible for several complications in CKD. GH is a protein based peptide hormone which directly or indirectly regulates renal functions to ensure homeostasis. We investigated the effects of growth hormone on plasminogen activators (PA) in rat kidney, PA and plasminogen activator inhibitor (PAI), glucose and fibrinogen in plasma and serum lipid profile. Rats were injected daily with 250 mU GH kg-1 body weight subcutaneously for one week. Growth hormone treatment increased PA activity significantly in rat kidneys as compared to controls. No changes were seen in PA, PAI and fibrinogen levels in the plasma of two groups of rats. There was significant decrease in plasma glucose, total cholesterol and LDL-cholesterol levels in serum of treated group resulting in the decrease of HDL/LDL and total cholesterol/cholesterol ratios. However, triglycerides and VLDL showed significant higher activity in the serum of treated group as compared to controls. Our data suggests that GH administration might improve renal function by increasing PA activity in kidney as well as by reducing the cholesterol content in blood. GH may be effective in improving growth failure as it helps to maintain the normal homeostatic balance. 相似文献
307.
Narotam Sharma Veena Sharma Prem Raj Singh Shivani Sailwal Rajeev S. Kushwaha Rajesh K. Singh Satish C. Nautiyal Pankaj Mishra Tariq Masood R. K. Singh 《Indian journal of clinical biochemistry : IJCB》2013,28(3):305-308
Genitourinary tuberculosis is a disease of the genitourinary system which includes the entire urinary tract and reproductive system. Genital tuberculosis is an important cause of female infertility, especially in developing nations like India. In the present study, a total of 257 clinical specimens comprising of endometrial biopsy (109), endometrial curetting (42), menstrual blood (8), semen (17), placenta (11) and urine (70) were collected from patients and subjected for PCR, Culture and AFB detection. The endometrial biopsy, endometrial curetting, menstrual blood, semen, placenta, urine showed 30.2, 45.2,12.5, 5.8, 27.2, 31.4 %, positivity rate for tuberculosis by PCR, 7.3, 9.5, 25.0, 0, 9, 8.5 % by culture and 1.8, 2.3, 0, 0, 0, 2.8 % respectively by AFB smear. Being a novel, rapid technique, PCR is the method of choice for rapid diagnosis and management of genitourinary tuberculosis shared with the other concerned tests. This study reveals that genital tuberculosis can occur in any age group, however, the majority of patients were from reproductive age (nearly 75 % of them were from 20–45 years of age) group. 相似文献
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Hafedh Al-Shihi Sujeet Kumar Sharma Mohamed Sarrab 《Education and Information Technologies》2018,23(5):1805-1824
The proliferation of mobile computing technologies is playing major role in the growth of mobile learning (M-learning) market around the globe. The purpose of this paper is to develop a research model in the lines of commonly used models the Unified Theory of Acceptance and Use of Technology (UTAUT) and Technology Acceptance Model (TAM) by incorporating constructs namely flexibility learning, social learning, efficiency learning, enjoyment learning, suitability learning, and economic learning that can predict M-learning adoption in a developing country. The data were collected from 388 students from all major universities/colleges in the capital city (Muscat) of Oman. The neural network modeling was employed to predict M-learning adoption. The neural network modeling results showed that flexibility learning, social learning, efficiency learning, enjoyment learning, suitability learning, and economic learning variables have significant influence on the intention of students to accept mobile learning. The key outcomes of this study suggest important determinants that can assist academic administrators and telecommunication service providers to enhance the adoption of M-learning with the help of suitable strategy. 相似文献