Relationship Between Fetal Loss and Serum Gonadal Hormones Level in Experimental Antiphospholipid Syndrome Mouse

To investigate the effects of antiphospholipid antibodies on establishment of pregnancy and changes in hormones such as estradiol-17ß (E₂) and progesterone (P) levels in circulation. Hence, mice were immunized with human β2-Glycoprotein I (β2GPI) and the effect of these antibodies on fetuses weight, placental obsrvation, Serum levels of P and E₂ in pregnant mice, hematological were observed. Immunization of mice with human β₂-GPI resulted in elevated levels of antiphospholipid antibodies. The experimentally induced antiphospholipid syndrome mouse showed higher rate of fetal resorption, low number of viable fetuses, and “placental abnormalities”. In these animals, serum E₂ and P levels were reduced significantly. In addition, the blood cell variation among APS induced and control mice were determined. No significant variations were observed in number of Red Blood Cell count, White Blood Cell count and Hemoglobin content, while platelet number was significantly reduced as compared to control. These results clearly demonstrate that human β₂-GPI might be involved in causing gestational failure in APS by exerting their effect on serum hormones.     

基于GIS的巴基斯坦北部文化遗址时空分布特征及保护对策

巴基斯坦北部地区是历史上犍陀罗文化的中心区域,拥有大量的印度教、佛教和伊斯兰教文化遗址.借助考古文献资料、数字高程模型以及野外实地调查与验证数据,运用GIS空间分析方法,对巴基斯坦北部地区印度教、佛教和伊斯兰教文化遗址的时空分布特征、保存现状进行研究,并提出相应保护对策.结果 表明:巴基斯坦北部地区先后经历了印度教文化...     

Antibodies against free radical modified DNA in cancer patients

In this study we have modified DNA by exposing it to ultraviolet light in the presence of hydrogen peroxide. The modified DNA was probed for binding to the antibodies present in the sera of patients suffering from various types of cancer. Higher recognition of modified DNA, as compared to native DNA, by antibodies from cancer patients has got far reaching significance.     

Attenuation of oxidative stress in streptozotocin-induced diabetic rats by <Emphasis Type="Italic">Eucalyptus globulus</Emphasis>

In traditional medicine, Eucalyptus globulus (eucalyptus) was used for the treatment of diabetes mellitus. Hyperglycemia in diabetes has been associated with increased formation of reactive oxygen species (ROS) and oxidative damage to tissue compounds. The aim of this study was to evaluate the effects of eucalyptus in the diet (20 g/Kg) and drinking water (2.5 g/L) on lipid peroxidation, protein oxidation and antioxidant power in plasma and liver homogenate, as well as glycated-Hb (HbA_1C) of blood in streptozotocin-induced diabetic rats for a period of 4 weeks. Diabetes induced in rats by a single intraperitoneal injection of streptozotocin (STZ, 65 mg/Kg). At the end of the treatment period, the level of plasma glucose, plasma and liver malondialdehyde (MDA, the main product of lipid peroxidation), protein carbonyl (PC, one of the protein oxidation products) and HbA_1C increased and ferric reducing antioxidant power (FRAP) decreased in diabetic rats compared to normal rats. Eucalyptus administration for 4 weeks caused a significant decrease in the plasma glucose levels, plasma and liver MDA, PC and HbA_1C, also a concomitant increase in the levels of FRAP in diabetic treated rats. In conclusion, the present study showed that eucalyptus posses antioxidant activities. Eucalyptus probably restores antioxidant power, due to the improved hyperglycemia in streptozotocin-induced diabetic rats.     

我国单板U型场地滑雪队备战、参赛2010年温哥华冬奥会的心理训练

随着技术的不断成熟,对单板U型场地滑雪队运动员的心理能力要求越来越高。在2010年温哥华冬奥会上,我国单板U型场地滑雪队健儿取得了较好成绩,实现了历史突破。教练员和运动员都认为良好的心理状态是保证技术正常发挥的关键因素。对中国单板U型场地滑雪队温哥华冬奥会备战、参赛的心理准备情况进行总结,并展示相关案例,以期为运动员大赛心理准备研究和心理学工作者为运动队服务提供借鉴。     

A3CRank: An adaptive ranking method based on connectivity,content and click-through data

Due to the proliferation and abundance of information on the web, ranking algorithms play an important role in web search. Currently, there are some ranking algorithms based on content and connectivity such as BM25 and PageRank. Unfortunately, these algorithms have low precision and are not always satisfying for users. In this paper, we propose an adaptive method, called A3CRank, based on the content, connectivity, and click-through data triple. Our method tries to aggregate ranking algorithms such as BM25, PageRank, and TF-IDF. We have used reinforcement learning to incorporate user behavior and find a measure of user satisfaction for each ranking algorithm. Furthermore, OWA, an aggregation operator is used for merging the results of the various ranking algorithms. A3CRank adapts itself with user needs and makes use of user clicks to aggregate the results of ranking algorithms. A3CRank is designed to overcome some of the shortcomings of existing ranking algorithms by combining them together and producing an overall better ranking criterion. Experimental results indicate that A3CRank outperforms other combinational ranking algorithms such as Ranking SVM in terms of P@n and NDCG metrics. We have used 130 queries on University of California at Berkeley’s web to train and evaluate our method.     

Robust finite-time stabilizers for five-degree-of-freedom active magnetic bearing system

In this paper, the robust finite-time stabilization problem for a fully suspended five-degree-of-freedom active magnetic bearing system is addressed in the presence of external disturbances and additive uncertainties. By developing the nonsingular terminal sliding mode control and defining new nonlinear sliding surfaces, three separate classes of stabilizers are proposed to regulate and place the suspended rotor in the desired positions of air gaps within adjustable finite times. The suggested nonlinear sliding surfaces and designed control inputs for each class of stabilizers are two major differences between these stabilizers. It is mathematically proven that five control voltages of this system, designed by each class of the suggested stabilizers, are able to locate the suspended rotor at the centers of air gaps in the adjustable finite time which is summation of two reaching and settling finite times. Moreover, several new inequalities are extracted for determining the reaching and settling finite times related to the three classes of stabilizers. These inequalities reveal the dependencies between optional parameters of the proposed stabilizers and the mentioned finite times. Finally, numerical simulations are provided to illustrate the efficiency and good performance of each class of the designed stabilizers.     

Robust FOPID stabilization of retarded type fractional order plants with interval uncertainties and interval time delay

This study investigates the robust stability of the retarded type of interval fractional order plants with an interval time delay. To this end, the characteristic quasi-polynomial is divided into two terms. The first term is simply the denominator interval polynomial of the open loop system and the second term is the multiplication of the interval delay term in the numerator of the open loop system which is an interval polynomial. Each of these two terms of the characteristic quasi-polynomial makes their own value sets in the complex plane for a given frequency. In this paper, based on these two value sets and by using the zero exclusion principle, the robust stability of the closed loop system by applying a FOPID controller is analyzed. Finally, two numerical examples and an experimental verification are provided to demonstrate the effectiveness of the proposed method in the robust stabilization of fractional order plants with interval uncertainties and interval time delay.