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71.
At Curtin University, student perceptions of teaching and learning are gathered and reported online through eVALUate, a system that includes separate unit and teaching surveys. This article reports the development and validation of one of those surveys, the eVALUate teaching survey, which was developed based on the research literature on excellent teaching and evaluation. Since its development in 2006, repeated statistical testing using progressively larger samples has shown that the survey is valid and reliable. Moreover, the way in which the teaching survey is deployed within eVALUate, appended to the unit survey, which provides crucial institutional data, has significantly increased university response rates. This validated instrument is used for self-reflection, professional development, and rewarding staff. 相似文献
72.
Prashant Gupta A. Seetharaman John Rudolph Raj 《International Journal of Information Management》2013
Cloud computing has become the buzzword in the industry today. Though, it is not an entirely new concept but in today's digital age, it has become ubiquitous due to the proliferation of Internet, broadband, mobile devices, better bandwidth and mobility requirements for end-users (be it consumers, SMEs or enterprises). In this paper, the focus is on the perceived inclination of micro and small businesses (SMEs or SMBs) toward cloud computing and the benefits reaped by them. This paper presents five factors influencing the cloud usage by this business community, whose needs and business requirements are very different from large enterprises. Firstly, ease of use and convenience is the biggest favorable factor followed by security and privacy and then comes the cost reduction. The fourth factor reliability is ignored as SMEs do not consider cloud as reliable. Lastly but not the least, SMEs do not want to use cloud for sharing and collaboration and prefer their old conventional methods for sharing and collaborating with their stakeholders. 相似文献
73.
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75.
Using Polymerase Chain Reaction followed by Single Strand Conformation Polymorphism analysis, we studied thirty seven cases
of primary human breast cancer for the presence of mutations in exons 5 and 7 of p53 tumour suppressor gene. Only one of the
thirty seven tumours tested (2.7%) showed the electrophoretic mobility shift indicative of a mutation in exon 5 of the p53gene,
while no such mobility shift was noted in exon 7. Our finding is in contrast to the findings in previous studies, wherein
the mutation frequency has been reported to be 13–30% by direct DNA analysis. This may be related to the ethnicity and local
population prevalence rather than technique. 相似文献
76.
Aman Kumar Niti Kumari Vinny Gupta Rajendra Prasad 《Indian journal of clinical biochemistry : IJCB》2018,33(3):246-254
Renal cell carcinoma is the most common form of the kidney cancer accounting for more than 85% of the cases of which clear cell renal cell carcinoma (ccRCC) is the major histological subtype. The central molecular signature for ccRCC pathogenesis is the biallelic inactivation of VHL gene due to the presence of mutations/hyper-methylation/complete gene loss, which results in the downstream HIF activation. These events lead to increased tyrosine kinase receptor signalling pathways (RAS/MEK/ERK pathway, PI3K/AKT/mTOR pathway and NF-κB pathway), which through their downstream effector proteins causes the cell to proliferate and migrate. Recent studies have shown that VHL inactivation alone is not sufficient to induce the tumor. Mutations in numerous other genes that codes for chromatin modifiers (PBRM1, SETD2 and BAP1) and signalling proteins (PTEN and mTOR) have been identified along with activation of alternate signalling pathways like STAT and Sonic Hedgehog (SHH) pathway. It has also been shown that STAT pathway also works cooperatively with HIF to enhance the tumor progression. However, SHH pathway reactivation resulted in tumor regardless of the VHL status, indicating the complex nature of the tumor at the molecular level. Therefore, understanding the complete aetiology of ccRCC is important for future therapeutics. 相似文献
77.
78.
Sanjiv Gupta K. N. Singh V. Bapat V. Mishra D. K. Agarwal P. Gupta 《Indian journal of clinical biochemistry : IJCB》2008,23(1):89-91
The comparative diagnostic efficacy of two cardiac markers: CK-MB and cTn-T, has scarcely been investigated in Indian patients
of acute myocardial infarction. The present study was conducted for the same objective. The present study comprised of 59
patients. Males were 44 (75%) and females were 15 (25 %). The age of patients ranged from 32–84 years with mean age of 62.8
yrs. The mean age of males and females were 60 and 63 yrs respectively. All patients presented with history of chest pain
with a 12 leads ECG proven MI (ST Elevation, discordant T-waves). CK-MB was estimated in peripheral blood samples at 0,24,48
and 72 hours by an autoanalyzer. Following 12 hours of admission bed side Troponin-T test was done employing cTn-T marker
kit. Initially (0 hr), in 50% patients CK-MB was elevated. By end of 24 hours all the patients were CKMB positive and peak
level was attained at 24 hrs. Then it tended to decline over next 48 hrs. There were no false positive or negative results.
The cTn-T test was positive only in 22 % of ECG positive infarctions. However, the cTn-T positive cases were always accompanied
by a higher CK-MB levels. A significantly lower cTn-T positive cases in Indian patients can only be attributed to some difference
in amino acid sequence of Indian cTn-T and occidental cTn-T. A larger study from other Indian cardiac centers can either substantiate
or contradict our results. 相似文献
79.
Shailja Gupta Sakshi Sodhi Jaskiran Kaur Jaskiran Yamini 《Indian journal of clinical biochemistry : IJCB》2009,24(2):208-210
Hypomagnesaemia is common finding in current medical practice mainly in critically ill, post-operative patients and patients
admitted to ICU in tertiary cancer cases. Magnesium has been directly implicated in hypokalemia, hypocalcaemia and dysrrthymias.
We report a case of 60 year old patient, suffering from rectal carcinoma for a period of one year with confirmed hypokalemia,
hypocalcaemia and hyponatremia. Magnesium supplementation corrected the underlying multiple electrolyte disturbances in the
patient thus, establishing a positive correlation of magnesium with sodium, potassium and calcium. 相似文献
80.
Vaneet Kaur Minni Verma Amandeep Kaur Shalini Gupta Kamaljit Singh 《Indian journal of clinical biochemistry : IJCB》2012,27(3):290-295
Overnight fasting samples of 1,031 apparently healthy people of Punjab visiting the hospital over a period of 3 years were tested for serum lipid profile. The mean ± SD of serum total cholesterol, triglycerides, high density lipoprotein cholesterol, low density lipoprotein cholesterol and very low density lipoprotein cholesterol in mg/dl were 182.2 ± 33.9, 122.4 ± 33.4, 44.1 ± 6.8, 113.9 ± 32.0, 24.6 ± 7.1 respectively. When these subjects were grouped according to age and sex, no appreciable difference was observed between most of the groups. Serum triglycerides were found to be low and HDL-C was high in females when compared with males of similar age and vice versa. With advancing age, total cholesterol and low density lipoprotein cholesterol levels were found to be higher in women. The present study suggests that the obtained lipid values should be taken into consideration during clinical evaluation. 相似文献