A Structured Approach to Honours Undergraduate Research Course, Evaluation Rubrics and Assessment

This paper presents a new approach to the Honours Undergraduate Research Course design and implementation. The course design process, assessment and evaluation rubrics are provided. Lessons learned and the experience of the faced challenges and opportunities for two cohort offerings of the course during the winter terms of 2011 and 2012 are highlighted. Assessments show that major benefits include increasing interaction with the faculty and increasing intellectual maturity, skills, knowledge and confidence for the students and for the faculty, the furthering of research projects by the participation of undergraduate students. The course can serve as a model that can be easily adapted for use across the disciplines of science, technology, engineering and mathematics.     

Investigating the use and effectiveness of diverse types of materials in the delivery and support of lab sessions for multimedia subjects and students

This research study explores the use of different lab material, investigating which types of materials contribute the most to the delivery and support of laboratory (lab) sessions to design, skill‐based and technical courses in higher education in the UK. A qualitative research methodology was employed for this investigation and included both key stakeholders in academia, including 75 students and 12 tutors. An investigation was also conducted tracking student activity on the university's e‐learning facility (U‐link). Our key findings indicate that overall electronic material is considered the most effective type of material for the delivery of a lab session. This is followed by print, video and lastly audio material according to student responses and video, print and audio material according to tutor responses. Student and tutor responses varied per individual module/subject area. Video material was regarded by students and tutors as the most effective type for the delivery of skill‐based lab sessions and generally for independent learning, and electronic material was regarded as the most effective type for the delivery of technical and design lab sessions. Lastly, student tracking revealed that the introduction of video lab material in two modules increased the average time spent by students on U‐link by 58% for the technical module and 97% for the skill‐based module respectively.     

Preliminary studies on the hypoglycemic effect of <Emphasis Type="Italic">Peganum harmala</Emphasis> L. Seeds ethanol extract on normal and streptozotocin induced diabetic rats

Peganum harmala L. (Zygophyllaceae) is a traditional medicine used for the treatment of variety of human ailments, including antidepression, hallucination, antileishmaniasis etc. We report for first time the hypoglycemic activity of the ethanolic extract of this plant at two dose levels of 150 and 250mg/kg bw in sucrose challenged normal as well as in rats with streptozotocin induced diabetes. The oral administration of ethanolic extract causes maximum fall of blood glucose level to 22.9% (p<0.05) and 29.4% (p<0.01) respectively with the two doses in normal and 30.3% (p<0.01) and 48.4% (p<0.001) in diabetic rats. The standard drug metformin treated group showed 28.0% (p<0.01) and 45.5% (p<0.001) respectively in normal and diabetic rats. The above results show that the ethanolic extract of P. harmala is as effective as metformin in reducing the blood glucose levels of normoglycemic and streptozotocin-induced diabetic rats.     

Savouring Rajasthan's Shiksha Karmi in a remote village: the prospect of dismantling the student-teacher divide

The Shiksha Karmi Project in Rajasthan, one of the most educationally challenged states, is at the frontiers of alternative models of primary education in India. The key ideas underlying this model are: (i) the taking over of ‘sick’ schools in remote regions of the state and turning them around, (ii) creating new schools driven by demand from the ground, (iii) human resource investments to train local village teachers, (iv) strong linkages between the school and the community built upon a spirit of voluntarism, (v) an explicit movement toward gender equity and (vi) a bold attempt at the universalization of primary education through a combination of formal and non-formal institutions. This article provides a grounded feel for the Shiksha Karmi Project in a stellar school, Meena Dant Ka Pura. While the case highlights the shortage of locally based female teachers in the entire Shiksha Karmi Project, it also suggests the very real possibility of employing Shiksha Karmi Project alumni and higher grade students in teaching roles. Overall, primary education in India has much to learn from the Shiksha Karmi Project experience.     

Leucine125Valine (Leu125Val) Gene Polymorphism of Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) and Myocardial Infarction in Indian Population

Platelet-endothelial cell adhesion molecule-1 (PECAM-1) has role in atherosclerotic plaque development as well as in thrombosis leading to myocardial infarction (MI). Present study was aimed to analyse the association of PECAM-1 Leu125Val gene polymorphism with MI in Indian population. Subjects included healthy individuals as control (N = 116) and MI patients (N = 100) divided into two groups; MI patients at presentation of the acute event (MI-Group-1, N = 46) and patients with recent event of MI stabilized with treatment 4.5 days from their symptoms (MI-Group-2, N = 54). The difference in the distribution of Leu125Val genotype frequencies of controls and patients did not reach statistical significance. However Leu allele frequency (0.57) was more associated with MI patients as compared to control (0.504). sPECAM-1 levels were significantly elevated in patients at acute event of MI (MI-Group-1) by 44.1% (P = 0.009) as compared to controls and by 95.2% (P = 0.001) as compared to stabilized MI patients (MI-Group-2).     

A descriptive model of innovation and creativity in organizations: a synthesis of research and practice

Based on a review of the reported theoretical advances that are affirmed by empirical works from published management practice, this paper finds that innovation is an outcome of an intentional and designed effort of the organization, and synthesizes the findings for enhancing creativity and innovation by developing three antecedents that positively influence innovation in organizations: (1) the garnered knowledge, (2) the presence of a knowledge-supporting culture, and (3) the accumulation of social capital. The paper also provides a summary of transferable management practices that organizations are employing to enhance innovation and productivity.     

A genetically modified fuzzy linear discriminant analysis for face recognition

This paper addresses the face recognition problem through a modification of the Fuzzy Fisherface classification method. In conventional methods, the relationship of each face to a class is assumed to be crisp. The Fuzzy Fisherface method introduces a gradual level of assignment of each face pattern to a class, using a membership grading based upon the K-Nearest Neighbor (KNN) algorithm. This method was further modified by incorporating the membership grade of each face pattern into the calculation of the between-class and within-class scatter matrices, termed as Complete Fuzzy LDA (CFLDA). The present work aims at improving the assignment of class membership by improving the parameters of the membership functions. A genetic algorithm is employed to optimize these parameters by searching the parameter space. Furthermore, the genetic algorithm is used to find the optimal number of nearest neighbors to be considered during the training phase. The experiments were performed on the Olivetti Research Laboratory (ORL) face image database and the results show consistent improvement in the recognition rate when compared to the results from other techniques applied on the same database and reported in literature.     

Evaluation of serum adenosine deaminase and 5′-nucleotidase activities as probable markers in ovarian cancer

Adenosine deaminase (ADA) and 5′-nucleotidase (5′-NT) activities were measured in sera of patients with ovarian cancer and patients with benign ovarian tumour. The results were compared with that of a control group consisting of healthy women. ADA levels were significantly increased (P<0.001) in the ovarian cancer group (n=50) but not in the benign group (n=28) when compared to the controls (n=20). The results indicate that ADA and 5′-NT levels may help to differentiate malignant conditions from benign tumours of the ovary in addition to the existing tests such as serum CA-125 levels and histopathological study.     

MMP 9 Gene Promoter Polymorphism in Gastric Cancer

Matrix metalloproteinase-9 (gelatinase B) plays a key role in cancer invasion and metastasis by degrading the extracellular matrix and basement membrane barriers. A cytosine (C) > thymidine (T) single nucleotide polymorphism (SNP) at position −1562 in the MMP-9 promoter is reported to influence the expression of the gene. Genotyping of MMP-9 −1562 C→T promoter polymorphism in 140 gastric cancer patients and 132 healthy control subjects was carried out in order to evaluate its association with progression and development of gastric cancer. The SNP was genotyped by tetra-primer amplification refractory mutation system-polymerase chain reaction followed by agarose gel electrophoresis. Statistical methods were adopted to test for the significance of the results. Risk factor profile of the patients revealed age above 50 years, smoking, alcoholism as the factors associated with the disease. The distribution of genotype frequencies in gastric cancer patients were 28.7 % of CC, 45.5 % of CT and 25.7 % of TT, whereas in control subjects 31.8 % of CC, 53.03 % of CT and 15.15 % of TT, respectively. The allelic frequencies were 51.51 % of C and 48.48 % of T in patient group and 58.33 % of C and 41.66 % of T in controls respectively. The present study shows the possible association of epidemiological risk factors with gastric cancer. There is an increased frequency of T allele in the disease compared to control subjects. However, there is no association of the MMP-9 −1562 C→T promoter polymorphism in the development of gastric cancer.