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In this paper, we investigate the interplay of clinical knowledge and technological capabilities in the recent development of HIV/AIDS treatments and offer qualitative and quantitative evidence from the empirical setting of Italian practice. The study contributes to the literature on the co-evolution of physical and social technologies in medical innovation by showing how professional guidelines, systematic evaluative research and local coordination mechanisms contribute actively to the resolution of the uncertainty that surrounds technological advances, while leaving room for largely discretional therapeutic choices. The resulting variety in implementation strategies improves health outcomes, but may reduce productive efficiency.  相似文献   
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美国博士后工作已经有一百多年的历史,其发展经验表明,社会科学领域需要博士后工作。本文在梳理我国社会科学领域博士后工作的历史、描述发展现状的基础上,重点分析了我国社会科学领域博士后工作中遇到的一些现实问题,如培养方式单一、经费较少、对人才成长的作用没有理工科明显、流动站发展定位不清等。  相似文献   
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The vegetative stratum is a layer of existence that is inherent not only in plants. Here, I propose to look at how vegetative life – or, the vegetative mode of existence – affects cities. The vegetative mode of existence is not focused on activities, routines, achievements. Here appears a city that is not industrial or industrious. When the industrious city retreats, or falls apart, the vegetative stratum becomes visible. The vegetative city is a city without any central nervous system. I suggest the interpretation of the vegetative city as a hopeful manifestation of the urban that only takes place when the time is ripe.  相似文献   
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Abstract

The aim of this study was to determine potential relationships between anthropometric parameters and athletic performance with special consideration to repeated-sprint ability (RSA). Sixteen players of the senior male Qatar national soccer team performed a series of anthropometric and physical tests including countermovement jumps without (CMJ) and with free arms (CMJwA), straight-line 20 m sprint, RSA (6 × 35 m with 10 s recovery) and incremental field test. Significant (P < 0.05) relationships occurred between muscle-to-bone ratio and both CMJs height (r ranging from 0.56 to 0.69) as well as with all RSA-related variables (r < –0.53 for sprinting times and r = 0.54 for maximal sprinting speed) with the exception of the sprint decrement score (Sdec). The sum of six skinfolds and adipose mass index were largely correlated with Sdec (r = 0.68, P < 0.01 and r = 0.55, P < 0.05, respectively) but not with total time (TT, r = 0.44 and 0.33, P > 0.05, respectively) or any standard athletic tests. Multiple regression analyses indicated that muscular cross-sectional area for mid-thigh, adipose index, straight-line 20 m time, maximal sprinting speed and CMJwA are the strongest predictors of Sdec (r2 = 0.89) and TT (r2 = 0.95) during our RSA test. In the Qatar national soccer team, players’ power-related qualities and RSA are associated with a high muscular profile and a low adiposity. This supports the relevance of explosive power for the soccer players and the larger importance of neuromuscular qualities determining the RSA.  相似文献   
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Teens' own thoughts on fostering safe sexual practice are important perspectives in promoting adolescent sexual health yet are relatively absent in the literature. This focus group study explored teens' perceptions about the supports and challenges that exist as teens strive to engage in healthy sexual practices. Seventy-five teens participated in 11 focus groups using a semi-structured interview guide. School-based health centers provided the setting and facilitated sample recruitment. Focus groups were audiorecorded and transcribed verbatim. Data were analyzed using the focus group guide as a template and typologies, or clusters of concepts, were extracted to establish teen perceptions of the factors that support and challenge their ability to engage in safe sexual practices. The socio-ecological model provided the framework to identify these factors within the individual, family/parent, relational (peer/partner), community, or societal spheres of influence. Results discussed the importance of parents, the value of confidentiality, respect for teen decision-making, relationships skills, developmental aspects of the adolescent years, and social interpretations of gender. These findings revealed important considerations as adults develop policies, messages, and programs designed to promote safe sexual behavior in teens.  相似文献   
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This study, framed by the component model of reading (CMR), examined the relative importance of kindergarten-entry predictors of first grade reading performance. Specifically, elements within the ecological domain included dialect, maternal education, amount of preschool, and home literacy; elements within the psychological domain included teacher-reported academic competence, social skills, and behavior; and elements within the cognitive domain included initial vocabulary, phonological, and morpho-syntactic skills, and alphabetic and word recognition skills. Data were obtained for 224 culturally diverse kindergarteners (58% Black, 34% White, and 8% Hispanic or other; 58% received free or reduced-price lunch) from a larger study conducted in seven predominantly high poverty schools (n = 20 classrooms) in a midsized city school district in northern Florida. Results from a hierarchical multiple regression (with variables in the ecological domain entered first, followed by the psychological and cognitive domains) revealed a model that explained roughly 56% of the variance in first grade reading achievement, using fall-of-kindergarten predictors. Letter-word reading and morpho-syntactic skill were the strongest significant predictors. The findings largely support the CMR model as a means to understand individual differences in reading acquisition and, in turn, to support data-based instructional decisions for a wider range of children.  相似文献   
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