The dispersion of research performance within and between universities as a potential indicator of the competitive intensity in higher education systems

Higher education systems in competitive environments generally present top universities, that are able to attract top scientists, top students and public and private financing, with notable socio-economic benefits in their region. The same does not hold true for non-competitive systems. In this study we will measure the dispersion of research performance within and between universities in the Italian university system, typically non-competitive. We will also investigate the level of correlation that occurs between performance in research and its dispersion in universities. The findings may represent a first benchmark for similar studies in other nations. Furthermore, they lead to policy indications, questioning the effectiveness of selective funding of universities based on national research assessment exercises. The field of observation is composed of all Italian universities active in the hard sciences. Research performance will be evaluated using a bibliometric approach, through publications indexed in the Web of Science between 2004 and 2008.     

Revisiting the scaling of citations for research assessment

Over the past decade, national research evaluation exercises, traditionally conducted using the peer review method, have begun opening to bibliometric indicators. The citations received by a publication are assumed as proxy for its quality, but they require standardization prior to use in comparative evaluation of organizations or individual scientists: the citation data must be standardized, due to the varying citation behavior across research fields. The objective of this paper is to compare the effectiveness of the different methods of normalizing citations, in order to provide useful indications to research assessment practitioners. Simulating a typical national research assessment exercise, he analysis is conducted for all subject categories in the hard sciences and is based on the Thomson Reuters Science Citation Index-Expanded^®. Comparisons show that the citations average is the most effective scaling parameter, when the average is based only on the publications actually cited.     

Exercise training and impaired glucose tolerance in obese humans

Individuals with impaired glucose tolerance (IGT) are at greater risk of developing diabetes than in normoglycaemia. The aim of this study was to examine the effects of 12-weeks exercise training in obese humans with IGT. Eleven participants (6 males and 5 females; 49±9 years; mean Body Mass Index (BMI) 32.4 kg · m(-2)), completed a 12-week brisk walking intervention (30 min per day, five days a week (d · wk(-1)), at 65% of age-predicted maximal heart rate (HR(max)). Anthropometric measurements, dietary intake, pulse wave velocity (PWV, to determine arterial stiffness) and blood pressure (BP) were examined at baseline and post intervention. Fasting blood glucose, glycosylated haemoglobin, insulin, blood lipids, indices of oxidative stress and inflammation (lipid hydroperoxides; superoxide dismutase; multimeric adiponectin concentration and high-sensitivity C-reactive protein) were also determined. Post intervention, PWV (9.08±1.27 m · s(-1) vs. 8.39±1.21 m · s(-1)), systolic BP (145.4±14.5 vs. 135.8±14.9 mmHg), triglycerides (1.52±0.53 mmol · L(-1) vs. 1.31±0.54 mmol · L(-1)), lipid hydroperoxides (1.20±0.47 μM · L(-1) vs. 0.79±0.32 μM · L(-1)) and anthropometric measures decreased significantly (P < 0.05). Moderate intensity exercise training improves upper limb vascular function in obese humans with IGT, possibly by improving triglyceride metabolism, which may subsequently reduce oxidative stress. These changes were independent of multimeric adiponectin modification and alterations in other blood biomarkers.     

Comparison of Freelite and N-Latex serum free light chain assays: a critical review

IntroductionThe measurement of serum free light chain (FLC) represents a fundamental aspect on the assessment of patients with monoclonal gammopathies (MG). Different analytical methods for FLC have become available with the possibility to obtain different value with a substantial impact on the assessment of patients with MG. This study aimed to evaluate FLC results obtained with two different assays and how the difference value obtained can impact in the patient’s assessment.Materials and methodsNinety-three patient serum samples that underwent analysis for FLC with two different methods, Serum Freelite (The Binding Site, Birmingham, UK) and N-Latex FLC (Siemens, Marburg, Germany), were included in this retrospective study. Statistical analysis was performed to evaluate correlation, difference, and the grade of concordance between the results obtained with the two methods.ResultsSignificant statistical differences between the results obtained from the two methods were found (P < 0.05). A good correlation was found (0.99 for κ FLC, 0.95 for λ FLC, and 0.94 for the κ/λ ratio, respectively). We found a weighted kappa value of 0.65 for κ/λ ratio, 0.65 for λ FLC and 0.90 for κ FLC. A positive bias found with the Bland-Altman plot mirrors overestimation of κ FLC and κ/λ ratio with Freelite compared to N-Latex, whilst a negative bias underscores underestimation of λ FLC by Freelite compared to N-Latex.ConclusionAlthough in general the concordance between Freelite and N-Latex appears satisfactory, several discrepancies could be evidenced and consequently the two assays are not interchangeable.     

Rats do show primacy and recency effects in memory for lists of spatial locations: A reply to Gaffan

It has been demonstrated that rats display both primacy and recency effects in list-learning experiments for both item- and order-recognition memory for spatial location information. Contrary to a suggestion made by Gaffan (1992) that previous demonstrations of primacy effects in rats are not valid due to statistical and methodological problems, we show that (1) it is not likely that our results are due to experimenter bias and/or nonindependence of trials, (2) primacy and recency effects are obtained whether or not one uses a training criterion, and (3) when many of the published reports from our laboratory are combined, the number of subjects and trials are sufficient to evaluate the validity of primacy and recency effects in list-learning experiments.     

When it comes round to marking assignments: how to impress and how to ‘distress’ lecturers …

What do lecturers look for when marking essays? What impresses them and what frustrates them? In this paper, we present the results of a survey which asked lecturers to address these questions. Thirty‐two lecturers responded to an email survey in which they listed the problems they found most frustrating when marking essays and the factors which most impressed them. This resulted in 206 comments related to sources of frustration and 139 comments listing factors which impress them. The comments were then coded into themes and ranked in order of importance by 16 lecturers from the original sample. The results highlight a range of issues that may be useful for lecturers when discussing assignments, and instructive for students when writing their assignments.