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51.
52.
India’s educational policy on inclusive education for students with disabilities is in sync with general global developments. Especially in the last couple of years there have been significant legislative achievements towards this endeavour. However, the implementation of inclusive education remains elusive. Besides this, teachers’ preparedness for inclusion has received little attention. This survey study had two aims. Firstly, we aimed at finding or constructing a reliable instrument to measure three aspects: the attitudes, knowledge about disability and inclusive teaching methods of regular schoolteachers. Secondly, we aimed to describe the outcomes of the three aspects. For attitudes and teaching methods we found a reliable instrument, which was selected for the usage in this study. We constructed and assessed the reliability of a scale in measuring knowledge about four disabilities: attention deficit hyperactivity disorder, dyslexia, intellectual disability and autistic spectrum disorder in pilot and main studies. The results revealed that teachers hold neutral attitudes towards inclusive education. Their knowledge about disabilities, however, was low, but knowledge about inclusive teaching methods was acceptable, which was a significant finding. The practical implications for preparing teachers to work towards inclusion are also discussed. 相似文献
53.
Yashika Gupta V. Mallika D. K. Srivastava 《Indian journal of clinical biochemistry : IJCB》2003,18(1):35-45
High plasma concentration of low-density lipoprotein (LDL) is associated with increased risk of atherosclerosis. Modified
forms of LDL, especially oxidized LDL play a major role in its pathogenesis. This article gives detailed insight into the
kinetics ofin vitro LDL oxidation by copper at different concentrations in normal and high-risk group subjects. Basal level of oxidatively modified
LDL was significantly higher in ischaemic heart disease (IHD) and IHD hyperlipidemic subjects compared to normolipidemic and,
hyperlipidemic control subjects, respectively. Derivatization of amino groups of apo-lipoprotein as monitored by estimating
free amino groups concentration, was significantly higher in high-risk group and established IHD cases. Kinetics of oxidation
was studied with two different concentrations of CuSO4 (2.5 mM and 7.5 mM). thiobarbituric acid reactive substances (TBARS) level increases with time, and up to 95% oxidation was
observed in 8 hr. About 60–65% less free amino groups were observed in native-LDL isolated from IHD patients compared to normal
subjects. Study also showed an increase in two oxidative products studied, 20α-OH-cholesterol and 4-cholesten-3-one with oxidation
time accompanied by corresponding decrease in LDL cholesterol. Increase in oxidative species was more evident in high-risk
group and IHD patient. Basal level of oxidatively modified LDL measured in terms of TBARS was significantly higher in present
study, strongly support that the extent of LDL oxidation monitored as TBARS and FAG level in circulating-LDL could be used
as risk marker for high risk group. 相似文献
54.
Lipoprotein (a) levels in alcohol drinking and alcohol non-drinking coronary artery disease patients
S. Vasisht D. P. Agarwal H. S. Wasir L. M. Srivastava 《Indian journal of clinical biochemistry : IJCB》1996,11(2):176-179
This study examines the role of alcohol drinking on lipoprotein(a) [Lp(a)] levels in angiographically assessed coronary artery disease patients. A lower Lp (a) level was noted in the alcohol drinking group as compared to the alcohol non-drinking group. 相似文献
55.
Santosh Kumar Maurya Kanwal Raj Arvind Kumar Srivastava 《Indian journal of clinical biochemistry : IJCB》2009,24(4):404-409
The root of Glycyrrhiza glabra is a traditional medicine used mainly for the treatment of peptic ulcer, hepatitis C, pulmonary
and skin diseases, although clinical and experimental studies suggest that it has several other useful pharmacological properties
such as antiinflammatory, antiviral, antimicrobial, antioxidative, anticancer activities, immunomodulatory, hepatoprotective
and cardioprotective effects. Glycyrrhizinic acid, a major component of licorice, has antiulcer effect by raising the local
concentration of prostaglandins that promote mucous secretion and cell proliferation in the stomach. Glycyrrhizin shows hepatoprotective
effect by preventing changes in cell membrane permeability, inhibiting phospholipase A2 (PLA2) and increasing survival rate of hepatocytes. Glabridin has effect in melanogenesis and inflammation by inhibiting the tyrosinase
activity of melanocytes. α-glycyhrritinic acid exhibits anti-inflammatory activity by inhibiting glucocorticoid metabolism.
In present study ethanolic (95%) extract of root of Glycyrrhiza glabra and its fractions were investigated for its antidyslipidaemic
activity on HFD induced dyslipidaemic hamsters. Ethanolic extract and its ethyl acetate soluble, water soluble and hexane
soluble fractions decreased serum level of total cholesterol by 25.9, 38.0, 39.0 and 26.3%, respectively. On the other hand
ethanolic extract, ethyl acetate soluble, water soluble and hexane soluble fraction increased the serum HDL-cholesterol level
by 14.8, 34.3, 27.3 and 17.2%, respectively. Ethanolic extract, ethyl acetate fraction, aqueous fraction and hexane fraction
decreased triglyceride level by 31.3, 37.2, 41.2 and 28.9%, respectively. The reduction in LDL-cholesterol level by ethanolic
extract, ethyl acetate soluble fraction and water soluble fraction were 43.9, 31.0, 33.4 and 24.6%, respectively. 相似文献
56.
In this paper a method of electrospinning conducting and nonconducting biphasic Janus nanofibers using microfluidic polydimethylsiloxane (PDMS)-based manifolds is described. Key benefits of using microfluidic devices for nanofiber synthesis include rapid prototyping, ease of fabrication, and the ability to spin multiple Janus fibers in parallel through arrays of individual microchannels. Biphasic Janus nanofibers of polyvinylpyrrolidone (PVP)+polypyrrole (PPy)∕PVP nanofibers with an average diameter of 250 nm were successfully fabricated using elastomeric microfluidic devices. Fiber characterization and confirmation of the Janus morphology was subsequently carried out using a combination of scanning electron microscopy, energy dispersion spectroscopy, and transmission electron microscopy. 相似文献
57.
58.
Dimple Anand Sabari Das Sumit Ray Seema Bhargava Lalit Mohan Srivastava 《Indian journal of clinical biochemistry : IJCB》2014,29(1):93-96
Sepsis suffers from lack of specific clinical symptoms which contribute to one of the major causes of mortality. In the present study, our aim was to evaluate the role of a recent biomarker Procalcitonin (PCT) in predicting organ dysfunction. 71 patients admitted with sepsis were included in the study. PCT levels were measured at 0, 24, 72 h and 7th day and sequential organ failure assessment score (SOFA) scores were calculated. PCT levels significantly decreased (p < 0.001) in 89.3 % of surviving patients, whereas, in 60 % non surviving patients the PCT level increased significantly (p < 0.001). A significant positive correlation between PCT and SOFA score was observed in survivors at each hour. These observations indicate that PCT concentration is significantly associated with severity of multi organ dysfunction and also helps in determining the prognosis of septic patients. 相似文献
59.
Srivastava N Prakash J Lakhan R Agarwal CG Pant DC Mittal B 《Indian journal of clinical biochemistry : IJCB》2011,26(2):125-130
Glucocorticoids and its receptor are known to be involved in the dysregulation of hormone and lipid levels. Therefore, we
evaluated the association of Bcl1 gene polymorphism of glucocorticoids receptor (GCR) gene variant with hormone and lipid levels in Northern Indians obese. A total of 435 obese and non-obese age matched subjects
were included in the case–control study. Lipid and hormonal levels were estimated using standard protocols. Analysis of +646
C>G NR3C1 gene polymorphism was done using PCR–RFLP. The frequencies of GR Bcl1, C>G genotypes and alleles did not differ significantly (P > 0.05) between obese and non-obese. The +646 G allele carriers had higher waist to hip ratio, blood pressure, insulin and
glucose levels than non-carriers in obese subjects while diastolic blood pressure and glucose in non-obese. The NR3C1, +646 C>G polymorphism did not associate with obesity. However, the GG genotype may modulate blood pressure, blood glucose
and hormonal levels in northern Indians. 相似文献
60.