GCAT-SEEKquence: genome consortium for active teaching of undergraduates through increased faculty access to next-generation sequencing data

To transform undergraduate biology education, faculty need to provide opportunities for students to engage in the process of science. The rise of research approaches using next-generation (NextGen) sequencing has been impressive, but incorporation of such approaches into the undergraduate curriculum remains a major challenge. In this paper, we report proceedings of a National Science Foundation-funded workshop held July 11-14, 2011, at Juniata College. The purpose of the workshop was to develop a regional research coordination network for undergraduate biology education (RCN/UBE). The network is collaborating with a genome-sequencing core facility located at Pennsylvania State University (University Park) to enable undergraduate students and faculty at small colleges to access state-of-the-art sequencing technology. We aim to create a database of references, protocols, and raw data related to NextGen sequencing, and to find innovative ways to reduce costs related to sequencing and bioinformatics analysis. It was agreed that our regional network for NextGen sequencing could operate more effectively if it were partnered with the Genome Consortium for Active Teaching (GCAT) as a new arm of that consortium, entitled GCAT-SEEK(quence). This step would also permit the approach to be replicated elsewhere.     

Patterns of physical activity and overweight among 7-13-year-old Russian children: a 7-year nationally representative monitoring study

This is a repeated cross-sectional study of overweight and physical activity (PA) and inactivity patterns of successive samples of 7-13-year-old Russian children who were surveyed six times between 1995 and 2002 as part of the Russian Longitudinal Monitoring Survey. This analysis focused on moderate/vigorous (MOD/VIG) PA (e.g., active commuting to school, during school MOD/VIG PA as part of physical education classes, and/or before/after school MOD/VIG PA) and inactivity patterns (e.g, television viewing habits) obtained through parent proxy-reports of 3,507 boys (M age = 10.1 years, SD = 2.0; body mass index = 17.5 kg/m2, SD = 3.0) and 3,273 girls (M age = 10.1 years, SD = 2.0; body mass index = 17.2 kg/m2, SD = 3.0). Time spent in MOD/VIG PA appears to be on the rise, while the proportion of those actively commuting to school is decreasing, especially among girls.     

“语用”意识观照下的朗读教学策略

我们发现,当下的"语用"课堂,朗读正逐渐被边缘化。有人认为,课堂由"热闹"走向"安静",由"浮华"走向"实用",这正是"语用型"课堂走向"务实"与"高效"的表现。那么,朗读,对于培养小学生的语用能力,到底重不重要呢?在语用意识的观照下,我们又该如何实施好朗读的教学策略呢?这是本文要着重探讨的两个问题。     

Dyslipidaemia Associated with Type 2 Diabetics with Micro and Macrovascular Complications among Ghanaians

In this study, differences in lipid levels amongst diabetics with and without complications were assessed to determine lipid disorders that are associated with diabetic complications other than cardiovascular diseases. A Cross sectional study design was employed. The study included 288 diabetics and 108 non diabetics with different types of complications such as hypertension, nephropathy, neuropathy, and retinopathy. The mean serum total cholesterol was higher in patients with complications compared to those without complications and the non-diabetic controls. The normotensive diabetic patients had the lowest total cholesterol among the diabetic patients’ groups (4.65 ± 0.17 mmol/l) compared to the diabetics with hypertension (6.051 ± 0.20 mmol/l), retinopathy (6.26 ± 0.29 mmol/l), neuropathy (5.80 ± 0.17 mmol/l) and nephropathy patients 5.74 ± 0.26 mmol/l (P < 0.05). The prevalence of dyslipidaemia among diabetic subjects was between 19.2 and 84.0%. The study shows that, in addition to macrovascular complications, dyslipidaemia is common in type 2 diabetes mellitus patients with microvascular complications.     

Narrative therapy and children with hearing impairments

Narrative approaches to psychology converge around the idea that therapy is essentially a special kind of conversation that elicits a client's strengths, competencies, and solutions. The psychologist is seen to assist in creating conversations that reveal the client's expertise and empower the client to change. The narrative approach is potentially valuable to psychologists working with children with good oral language who are deaf or hard of hearing. Just as important, while the psychologist and the client explore and explicate complex issues within the problem-solving process, the "balance of power" is changed and the child becomes better able to assume control of the problem. Two case studies are used to explore the narrative process of "externalization" with children with good oral language who are deaf or hard of hearing.     

A microdevice for the creation of patent, three-dimensional endothelial cell-based microcirculatory networks

Microvascular network formation is a significant and challenging goal in the engineering of large three-dimensional artificial tissue structures. We show here the development of a fully patent, 3D endothelial cell (microvascular) microfluidic network that has a single inlet and outlet, created in only 28 h in a microdevice involving fluid flow equivalent to natural vasculature. Our microdevice features a tailored "multi-rung ladder" network, a stylized mimic of an arterial-to-venous pedicle, designed to also allow for systematic and reproducible cell seeding. Immunofluorescence staining revealed a highly contiguous endothelial monolayer (human umbilical vein endothelial cells) throughout the whole network after 24 h of continuous perfusion. This network persisted for up to 72 h of culture, providing a useful template from which the effects of surface chemistry, fluid flow, and environmental conditions on the development of artificial vascular networks ex vivo may be rapidly and robustly evaluated.     

Lawyer and counselor as an interdisciplinary team serving the terminally ill

Mental health professionals consult with the terminally ill and provide therapy to the client, spouse, and family. Some clients have been forewarned and have a carefully drafted estate plan that incorporates all the nuances of property and personal planning. In addition, the client may have an interest in donating his or her body or its parts as an anatomical gift or may inquire concerning the right to die a natural death. He or she may further be concerned with the appropriateness of a power of attorney or a living trust. Whatever the inquiry, the mental health professional should be ready, willing, and able to offer informed data regarding questions in these areas and then to serve with the attorney as an interdisciplinary team to respond quickly and effectively to these legitimate personal concerns.     

Perceptions among occupational and physical therapy students of a nontraditional methodology for teaching laboratory gross anatomy

This pilot study was designed to assess the perceptions of physical therapy (PT) and occupational therapy (OT) students regarding the use of computer-assisted pedagogy and prosection-oriented communications in the laboratory component of a human anatomy course at a comprehensive health sciences university in the southeastern United States. The goal was to determine whether student perceptions changed over the course of a summer session regarding verbal, visual, tactile, and web-based teaching methodologies. Pretest and post-test surveys were distributed online to students who volunteered to participate in the pilot study. Despite the relatively small sample size, statistically significant results indicated that PT and OT students who participated in this study perceived an improved ability to name major anatomical structures from memory, to draw major anatomical structures from memory, and to explain major anatomical relationships from memory. Students differed in their preferred learning styles. This study demonstrates that the combination of small group learning and digital web-based learning seems to increase PT and OT students' confidence in their anatomical knowledge. Further research is needed to determine which forms of integrated instruction lead to improved student performance in the human gross anatomy laboratory.     

Developing an interdisciplinary collaboration center in an academic Health Sciences Library

This article describes the evolution of the Health Sciences Library's plans for an interdisciplinary, technology-enhanced collaboration center, from a technology-driven space to one with a vision of support for peer-to-peer learning and research. The center offers an exciting opportunity to be an essential partner in collaborative and interdisciplinary programs such as the new Carolina Center for Exploratory Genetic Analysis. The Library is a centrally located and neutral place, which helps minimize geographical and territorial obstacles to effective collaboration. The collaboration center raises the Library's visibility and allows staff to demonstrate the value of knowledge resources, services, technology expertise, infrastructure, and facilities for group study and collaboration.     

用于快速帆船的高强度织物

最初为快速赛艇帆篷研制的复合织物有可能很快可能在降落伞上和探测气球上找到新的用途.