Optimism as a Candidate Health Asset: Exploring Its Links With Adolescent Quality of Life in Sweden

This study aims to understand the role that optimism could play in the context of a health asset approach to promote adolescent health-related quality of life (HRQOL). Adolescents (n = 948), between 11 and 16 years old from a medium-sized rural town in Sweden, answered questionnaires measuring optimism, pessimism, and HRQOL. The findings indicate a significant decrease in optimism and a significant increase in pessimism between early and midadolescence. The study has allowed us to present associational evidence of the links between optimism and HRQOL. This infers the potential of an optimistic orientation about the future to function as a health asset during adolescence and by implication may provide additional intervention tool in the planning of health promotion strategies.     

Adaptation During a Great Economic Recession: A Cohort Study of Greek and Immigrant Youth

This study examined how Greek and immigrant youth adapted to school life during the economic recession in Greece. Two cohorts of adolescents (M_age = 12.6 years) were compared, one assessed before the crisis and the other during the crisis (N = 1,057 and 1,052, respectively). Cohort findings were disaggregated by immigrant status, generation, and ethnic group. Crisis‐cohort youth experienced more economic problems, displayed worse conduct, higher levels of absenteeism, and lower self‐efficacy than precrisis youth. The cohorts did not differ in well‐being, school engagement, and academic achievement. Most crisis‐cohort groups showed a pervasive increase in conduct problems compared to the precrisis cohort. However, some of these groups also showed an increase in academic achievement.     

Inhalte und Strukturen prototypischer Merkmale in Fußballmannschaften

Members of a social group possess a shared social identity, which is individually represented as the group prototype. The prototype is the individual cognitive representation of all attributes, which best describes the group from the group members’ point of view. The aim of the study was to gather those attributes provided by group members of a soccer team and subsequently to describe and categorize them by means of a content analysis. Using one single open question, a total of 1581 attributes were assessed through n?=?278 soccer players (67?% male; M?=?23.5 years, SD?=?5.0 years) from 20 soccer teams. The data analysis was based on the qualitative content analysis described by Mayring (2010). Results show that the attributes mentioned by the team members can be divided into four distinct categories (social, psychological, sport specific, ecological). These categories result from intragroup synchronisations. Future research should examine which categories and subcategories seem to best represent the prototype in soccer teams.     

Development of a magnetic immunosorbent for on-chip preconcentration of amyloid �� isoforms: Representatives of Alzheimer��s disease biomarkers

Determination of amyloid β (Aβ) isoforms and in particular the proportion of the Aβ 1-42 isoform in cerebrospinal fluid (CSF) of patients suspected of Alzheimer’s disease might help in early diagnosis and treatment of that illness. Due to the low concentration of Aβ peptides in biological fluids, a preconcentration step prior to the detection step is often necessary. This study utilized on-chip immunoprecipitation, known as micro-immunoprecipitation (μIP). The technique uses an immunosorbent (IS) consisting of magnetic beads coated with specific anti-Aβ antibodies organized into an affinity microcolumn by a magnetic field. Our goal was to thoroughly describe the critical steps in developing the IS, such as selecting the proper beads and anti-Aβ antibodies, as well as optimizing the immobilization technique and μIP protocol. The latter includes selecting optimal elution conditions. Furthermore, we demonstrate the efficiency of anti-Aβ IS for μIP and specific capture of 5 Aβ peptides under optimized conditions using various subsequent analytical methods, including matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS), capillary electrophoresis, microchip electrophoresis, and immunoblotting. Synthetic Aβ peptides samples prepared in buffer and spiked in human CSF were analyzed. Finally, on-chip immunoprecipitation of Aβ peptides in human CSF sample was performed.     

Word length and word frequency affect eye movements in dyslexic children reading in a regular (German) orthography

We combined independently the word length and word frequency to examine if the difficulty of reading material affects eye movements in readers of German, which has high orthographic regularity, comparing the outcome with previous findings available in other languages. Sixteen carefully selected German-speaking dyslexic children (mean age, 9.5 years) and 16 age-matched controls read aloud four lists, each comprising ten unrelated words. The lists varied orthogonally in word length and word frequency: high-frequency, short; high-frequency, long; low-frequency, short; low-frequency, long. Eye movements were measured using a scanning laser ophthalmoscope (SLO). In dyslexic children, fixation durations and the number of saccades increased both with word length and word frequency. The percentage of regressions was only increased for low-frequency words. Most of these effects were qualitatively similar in the two groups, but stronger in dyslexic children, pointing to a deficient higher-level word processing, especially phonological deficit. The results indicate that reading eye movements in German children are modulated by the degree of difficulty, and orthographic regularity of the language can determine the nature of modulation. The findings suggest that, similar to Italian but unlike English readers, German children prefer indirect sub-lexical strategy of grapheme-phoneme conversion.