A systematic review of strength and conditioning programmes designed to improve fitness characteristics in golfers

It has been suggested that conditioning programmes have the potential to improve golf performance through fitness adaptations. The primary aim of this systematic review was to evaluate the effectiveness of conditioning programmes on measures of golf-related fitness and golf performance. Four electronic library databases were searched and the quality of the studies was assessed using criteria adapted from the Consolidated Standard of Reporting Trials statement. Thirteen studies satisfied our criteria for inclusion. Nine studies involved middle-aged to older male recreational golfers and four studies used younger more skilled golfers. Conditioning programmes involved the use of machine weights, free weights, medicine balls, and elastic bands, and most studies included a flexibility component. Most studies assessed changes in fitness characteristics and generally resulted in improvements. All but two of the studies assessed changes in club head speed and reported increases. The findings from this review suggest that strength and conditioning programmes can have a positive effect on the golf swing and fitness characteristics of golfers. The majority of studies in this review evaluated the effects of generic conditioning programmes on fitness characteristics and club head speed. Future studies should investigate the effects of more golf-specific strength and conditioning programmes to improve fitness and overall golf performance.     

Dynamic in situ chromosome immobilisation and DNA extraction using localized poly(N-isopropylacrylamide) phase transition

A method of in situ chromosome immobilisation and DNA extraction in a microfluidic polymer chip was presented. Light-induced local heating was used to induce poly(N-isopropylacrylamide) phase transition in order to create a hydrogel and embed a single chromosome such that it was immobilised. This was achieved with the use of a near-infrared laser focused on an absorption layer integrated in the polymer chip in close proximity to the microchannel. It was possible to proceed to DNA extraction while holding on the chromosome at an arbitrary location by introducing protease K into the microchannel.     

Young and Older Adults' Reading of Distracters

We used eye-tracking technology to examine young and older adults' performance in the reading with distraction paradigm. One-, 2- and 4-word distracters that formed meaningful phrases were used. There were marked age differences in fixation patterns. Young adults' fixations to the distracters and targets increased with distracter length, suggesting that they were attempting to integrate the distracters with the sentence and had more and more difficulty doing so as the distracters increased in length. Young adults did have better comprehension of the sentences than older adults and also better recognition memory for target words and distracters.     

Librarians in the Woods Hole Biomedical Informatics course

What has come to be known as the "Woods Hole course", Biomedical Informatics, is a week-long course sponsored by the National Library of Medicine which has been offered since 1992. Its participants include librarians, clinicians, educators, and administrators. This article discusses the content of the course and its applicability to medical librarians.     

New rationale for large metazoan embryo manipulations on chip-based devices

The lack of technologies that combine automated manipulation, sorting, as well as immobilization of single metazoan embryos remains the key obstacle to high-throughput organism-based ecotoxicological analysis and drug screening routines. Noticeably, the major obstacle hampering the automated trapping and arraying of millimetre-sized embryos on chip-based devices is their substantial size and mass, which lead to rapid gravitational-induced sedimentation and strong inertial forces. In this work, we present a comprehensive mechanistic and design rationale for manipulation and passive trapping of individual zebrafish embryos using only hydrodynamic forces. We provide evidence that by employing innovative design features, highly efficient hydrodynamic positioning of large embryos on a chip can be achieved. We also show how computational fluid dynamics-guided design and the Lagrangian particle tracking modeling can be used to optimize the chip performance. Importantly, we show that rapid prototyping and medium scale fabrication of miniaturized devices can be greatly accelerated by combining high-speed laser prototyping with replica moulding in poly(dimethylsiloxane) instead of conventional photolithography techniques. Our work establishes a new paradigm for chip-based manipulation of large multicellular organisms with diameters well above 1 mm and masses often exceeding 1 mg. Passive docking of large embryos is an attractive alternative to provide high level of automation while alleviating potentially deleterious effects associated with the use of active chip actuation. This greatly expands the capabilities of bioanalyses performed on small model organisms and offers numerous and currently inaccessible laboratory automation advantages.