Migration distance-based platelet function analysis in a microfluidic system

Aggregation and adhesion of platelets to the vascular wall are shear-dependent processes that play critical roles in hemostasis and thrombosis at vascular injury sites. In this study, we designed a simple and rapid assay of platelet aggregation and adhesion in a microfluidic system. A shearing mechanism using a rotating stirrer provided adjustable shear rate and shearing time and induced platelet activation. When sheared blood was driven through the microchannel under vacuum pressure, shear-activated platelets adhered to a collagen-coated surface, causing blood flow to significantly slow and eventually stop. To measure platelet adhesion and aggregation, the migration distance (MD) of blood through the microchannel was monitored. As the microstirrer speed increased, MD initially decreased exponentially but then increased beyond a critical rpm. For platelet-excluded blood samples, there were no changes in MD with increasing stirrer speed. These findings imply that the stirrer provided sufficiently high shear to activate platelets and that blood MD is a potentially valuable index for measuring the shear-dependence of platelet activation. Our microfluidic system is quick and simple, while providing a precise assay to measure the effects of shear on platelet aggregation and adhesion.     

CROSS CULTURAL VALIDATION OF THE TAT

This paper reports the results of a series of tests of the cross cultural validity of the Thematic Apperception Test as a psychometric instrument to gauge “motivation to succeed” in Atkinson's model of motivation. These tests represent the initial phase of a longer term project to test the validity, especially the criterion validity, of the Atkinson model in an Oriental context. Since the Atkinson model and the Thematic Apperception Test are both Occidental products, research on them (or with them) cannot proceed in the Orient without first testing for cultural bias. It is such testing that is reported in this paper.

The Thematic Apperception Test comprises a set of black and white drawings of white Americans dressed in the clothing of the late nineteen thirties. Each picture is designed to elicit a response by way of imagining the “before, during and after” of the situation depicted. However it is doubted whether young Oriental students would adequately relate to the depicted 1930s American whites to feel impelled to tell a story about them, which is what the Test is supposed to elicit. If such doubts were ratified by the research, it would not be advisable to use the Thematic Apperception Test in any subsequent work to test the Atkinson model. Even if our doubts proved unjustified (as it turned out), there would still remain the question of whether the Test reliably captured the need to achieve, which is a primary component of the Atkinson model.     

Meritocracy,policy and pedagogy: culture and the politics of recognition and redistribution in Singapore

ABSTRACT

Ideas about merit and the associated notion of a meritocracy have long been drawn upon to frame and understand a range of issues central to education policy. Little attention, however, is given to how in practice and through the workings of policy, meritocracy functions as an ideology that is struggled over by various social groups and pedagogic agents. Focusing on classroom pedagogic practices in Singapore, this article explores the ways in which in an ostensibly meritocratic education system, teachers interpret and negotiate ideas about culture to engage their students in the system’s low-progress tracks. We argue that these teachers are creatively resisting, even challenging official discourses of meritocracy and engaging in what Nancy Fraser calls struggles over recognition and redistribution.     

Developing online learning resources: Big data,social networks,and cloud computing to support pervasive knowledge

Utilizing online learning resources (OLR) from multi channels in learning activities promise extended benefits from traditional based learning-centred to a collaborative based learning-centred that emphasises pervasive learning anywhere and anytime. While compiling big data, cloud computing, and semantic web into OLR offer a broader spectrum of pervasive knowledge acquisition to enrich users’ experience in learning. In conventional learning practices, a student is perceived as a recipient of information and knowledge. However, nowadays students are empowered to involve in learning processes that play an active role in creating, extracting, and improving OLR collaborative learning platform and knowledge sharing as well as distributing. Researchers have employed contents analysis for reviewing literatures in peer-reviewed journals and interviews with the teachers who utilize OLR. In fact, researchers propose pervasive knowledge can address the need of integrating technologies like cloud computing, big data, Web 2.0, and Semantic Web. Pervasive knowledge redefines value added, variety, volume, and velocity of OLR, which is flexible in terms of resources adoption, knowledge acquisition, and technological implementation.     

Peer mentoring in engineering: (un)shared experience of undergraduate peer mentors and mentees

In this qualitative study, we explored the experiences of 26 engineering student mentors and mentees in a peer mentoring program. We found that mentors and mentees exploited the mentoring program’s fluid structure and situated social relationships to enact a specific type of academic/professional goal and identity conducive to their entry to one of two communities of practice, the on-campus engineering program community and the community of professional engineers. The mentoring program functioned as a social space in which identities of these students converged and diverged, creating a subtle tension and self-reflection in relation to the two different communities of practice that they pursued.     

Affective Outcomes of Cooperative Learning in Social Studies

This paper reports an experimental study involving the use of cooperative learning in a social studies classroom. The outcome variables discussed in the paper are pupil self-esteem and classroom climate. Over the period of the study, cooperative learning did not significantly improve the self-esteem of the pupils. However, pupils in the experimental group who were taught through the cooperative learning approach perceived classwork to be less difficult than the control pupils who worked individually. The control pupils also reported a decline in satisfaction with classwork and perceived more friction in their class. Interviews with the teacher and pupils showed favourable attitudes toward cooperative learning.     

Use of comics to enhance students’ learning for the development of the twenty-first century competencies in the mathematics classroom

Abstract

This paper discusses the use of comics in teaching mathematics in the secondary mathematics classroom. We explicate how the use of comics in teaching mathematics can prepare students for the twenty-first century competencies. We developed an alternative teaching package using comics for two lower secondary mathematics topics. This alternative teaching package consists of (1) several sets of comic strips expounding all related mathematical concepts in a lively way; (2) tiered practice questions for learning reinforcement; and (3) a set of proposed lesson outlines with suggestions on how to use the comics for mathematics teaching. We also report how one of the teachers in our study used this teaching package in her mathematics lessons. Her lessons were video-recorded and 11 students were interviewed to help us understand how the mathematics comics lessons were enacted and the students’ perception of comics as instruction. We identified instances in which the teacher tweaked the provided resource to further enhance student learning and incorporated elements of the twenty-first century competencies during her lessons. Through selected student interviews, we also identified instances in which students commented on their gain from the new approach from the perspective of the twenty-first century competencies.     

A holistic approach towards Information and Communication Technology (ICT) for addressing education challenges in Asia and the Pacific

Information and Communication Technology (ICT) offers opportunities for governments to address key education challenges of quality, equity, and efficiency. While governments and educational institutions in developed countries may have taken up these opportunities, many developing countries in Asia and the Pacific region have often missed them out. This may be due to countries’ socioeconomic settings, approaches towards design and implementation of the ICT in education plan, and investment on research and development of ICT in education. This paper explores the current challenges of education in Asia and the Pacific and explains how these challenges may be overcome by the strategic use of ICTs when a holistic approach towards ICT in education is adopted.     

Development of computer play pedagogy intervention for children with low conceptual understanding in basic mathematics operation using the dyscalculia feature approach

This study describes the development of a basic computer-based play pedagogy intervention using a dyscalculia-remedy-oriented approach such as repetition and number orientation manipulation, and the investigation of its effect on children displaying dyscalculia characteristics. This computer play was evaluated in a group of 50 seven-year-old Malaysian children, who were low achievers in mathematics subject and were divided into control and intervention group. The intervention group engaged with the newly developed computer play for an hour per day for five consecutive days, while the control group attended normal classroom learning for the same time period. Overall post-test scores indicated that children from the intervention group performed significantly better than the control group after the five-day intervention period by 57.9%. Number disorientation and arithmetic operation confusion, which are common amongst the children displaying dyscalculia characteristics, were also significantly reduced after the intervention. This implies that the children benefitted from the computer play.